6-Chlorothymine
- CAS No.
- 1627-28-7
- Chemical Name:
- 6-Chlorothymine
- Synonyms
- EOS-62068;6-Chlorothymine;6-Chloro-5-Methyluracil;6-CHLOROTHYMINE ISO 9001：2015 REACH;6-Chloro-5-Methyl-1H-pyriMidine-2,4-dione;6-CHLORO-5-METHYL-2,4(1H,3H)-PYRIMIDINEDIONE;6-Chloro-5-methylpyrimidine-2,4(1H,3H)-dione;2,4(1H,3H)-Pyrimidinedione, 6-chloro-5-methyl-
- CBNumber:
- CB01417548
- Molecular Formula:
- C5H5ClN2O2
- Molecular Weight:
- 160.56
- MDL Number:
- MOL File:
- 1627-28-7.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 |
6-Chlorothymine price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 309031 | 6-Chloro-5-methylpyrimidine-2,4(1H,3H)-dione | 1627-28-7 | 250.00mg | $50 | 2026-05-19 | Buy |
| Matrix Scientific | 309031 | 6-Chloro-5-methylpyrimidine-2,4(1H,3H)-dione | 1627-28-7 | 1.00g | $97 | 2026-05-19 | Buy |
| Matrix Scientific | 309031 | 6-Chloro-5-methylpyrimidine-2,4(1H,3H)-dione | 1627-28-7 | 5.00g | $441 | 2026-05-19 | Buy |
| aablocks | AA001T9R | 6-Chloro-5-methylpyrimidine-2,4(1H,3H)-dione 97% | 1627-28-7 | 100mg | $28 | 2026-05-28 | Buy |
| aablocks | AA001T9R | 6-Chloro-5-methylpyrimidine-2,4(1H,3H)-dione 97% | 1627-28-7 | 250mg | $34 | 2026-05-28 | Buy |
6-Chlorothymine Chemical Properties, Uses, Production
Synthesis
2417-22-3
1627-28-7
The general procedure for the synthesis of 6-chloro-5-methylpyrimidine-2,4(1H,3H)-dione from 5-methylbarbituric acid (CAS:2417-22-3) was as follows: under nitrogen protection, 5-methylbarbituric acid (9.40 g, 0.066 mol) and benzyltriethylammonium chloride (BTAC) (30.14 g, 0.13 mol) were suspended in trichloro phosphorus oxide (POCl3) (154 mL, 1.65 mol) and heated at 50 °C with stirring for 7 hours. Upon completion of the reaction, the mixture was cooled to room temperature and evaporated to dryness under vacuum. The residue was carefully quenched with 285 g of ice water at 0 °C and the slurry was subsequently placed in a refrigerator overnight. The precipitate was collected by filtration, washed with cold water and dried under vacuum in the presence of phosphorus pentoxide to give 6-chloro-5-methylpyrimidine-2,4(1H,3H)-dione (5.60 g, 0.035 mol, 53% yield) as a white solid. The melting point of the product was 270-272 °C. 1H NMR (300 MHz, DMSO-d6) δ (ppm): 11.81 (br s, 1H, NH), 11.32 (br s, 1H, NH), 1.82 (s, 3H, CH3). IR (KBr, ν cm-1): 3158 (NH), 3013,2814 (Csp2-H ), 1711,1647 (C=O), 1625 (C=C), 1491 (NH), 1424 (C-N), 891 (NH), 753 (C-Cl).
References
[1] European Journal of Medicinal Chemistry, 2012, vol. 54, p. 159 - 174
6-Chlorothymine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Jinan Trio PharmaTech Co., Ltd. | 0531-88811783 | sales@trio-pharmatech.com | China | 1856 | 62 |
| Shanghai ChuangYan Chemical Technology Co., Ltd. | 021-11111111 11111111111 | 546919421@qq.com | China | 3769 | 55 |
| ShangHai Angti Biotechnology Co., Ltd. | 13764913901 | info@angtibio.com | China | 4976 | 55 |
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6347 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Taian Jiaye Biotechnology Co.Ltd | 15318151873;13127280945 | 285424065@qq.com | China | 9961 | 55 |
| Shanghai Zhen Li Biological Technology Co., Ltd | 021-16621358918; 18516310516;16621358918;13045646768 | zhenlipharma888@163.com | China | 19060 | 58 |
| Aikon International Limited | 025-66061636 19370895928 | qqyang@aikonchem.com | China | 15810 | 58 |
| SHANGHAI FDC-CHEMICAL CO.,LTD | 021-61469567 13774476675 | sales@fdc-chemical.com | China | 10000 | 58 |
View Latest Price from 6-Chlorothymine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 6-CHLOROTHYMINE
1627-28-7
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2026-06-30 | 6-CHLOROTHYMINE
1627-28-7
|
1kg | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2019-09-11 | 6-CHLOROTHYMINE
1627-28-7
|
$5.00 | 1KG | 85.0-99.9% | 100g,1kg,5kg | Career Henan Chemical Co |
-
- 6-CHLOROTHYMINE
1627-28-7
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 6-CHLOROTHYMINE
1627-28-7
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- 6-CHLOROTHYMINE
1627-28-7
- $5.00
- 85.0-99.9%
- Career Henan Chemical Co
