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6-Bromoimidazo[1,2-a]pyridine

6-Bromoimidazo[1,2-a]pyridine Structure
6-Bromoimidazo[1,2-a]pyridine structure
CAS No.
6188-23-4
Chemical Name:
6-Bromoimidazo[1,2-a]pyridine
Synonyms
BUTTPARK 154\50-43;6-Bromoimidazo[1,2-a]pyri...;6-Bromoimidazo[1.2-alpyridine;6-BROMOIMIDAZO[1,2-A]PYRIDINE;6-BroMoiMidazolo[1,2-a]pyridine;6-BROMO-INIDAZO[1,2-A]-PYRIDINE;6-BroMo IMidazole[1,2-a]Pyridine;IMidazo[1,2-a]pyridine, 6-broMo-;6-Bromoimidazo[1,2-a]pyridine;6- BROMINE IMIDAZOLYL [ 1,2-A ] PYRIDINE
CBNumber:
CB0142414
Molecular Formula:
C7H5BrN2
Molecular Weight:
197.03
MDL Number:
MFCD06496200
MOL File:
6188-23-4.mol
MSDS File:
SDS
Last updated:2026-05-27 17:19:08
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6-Bromoimidazo[1,2-a]pyridine Properties

Melting point 76-78 °C
Boiling point 165 °C(Press: 1.5 Torr)
Density 1.69±0.1 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
pka 5.10±0.50(Predicted)
form crystalline needles
color Faint beige
Water Solubility slightly soluble in water.
InChI InChI=1S/C7H5BrN2/c8-6-1-2-7-9-3-4-10(7)5-6/h1-5H
InChIKey FXPMFQUOGYGTAM-UHFFFAOYSA-N
SMILES C12=NC=CN1C=C(Br)C=C2
CAS DataBase Reference 6188-23-4(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)
GHS06
Signal word  Warning
Hazard statements  H301-H315-H319-H335
Precautionary statements  P261-P280a-P301+P310a-P305+P351+P338-P405-P501a
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  22-26-36/37/39
WGK Germany  3
Hazard Note  Harmful
HazardClass  IRRITANT
HS Code  2933998090
Storage Class 11 - Combustible Solids
NFPA 704
0
2 0

6-Bromoimidazo[1,2-a]pyridine price More Price(63)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 750972 6-Bromoimidazo[1,2-a]pyridine 97% 6188-23-4 500mg $71 2023-06-20 Buy
TCI Chemical B5225 6-Bromoimidazo[1,2-a]pyridine min. 98.0 % 6188-23-4 1G $30 2026-04-30 Buy
TCI Chemical B5225 6-Bromoimidazo[1,2-a]pyridine min. 98.0 % 6188-23-4 10G $78 2026-04-30 Buy
AstaTech 31272 6-BROMOIMIDAZO[1,2-A]PYRIDINE 97% 6188-23-4 5G $10 2026-04-30 Buy
AstaTech 31272 6-BROMOIMIDAZO[1,2-A]PYRIDINE 97% 6188-23-4 25G $23 2026-04-30 Buy
Product number Packaging Price Buy
750972 500mg $71 Buy
B5225 1G $30 Buy
B5225 10G $78 Buy
31272 5G $10 Buy
31272 25G $23 Buy

6-Bromoimidazo[1,2-a]pyridine Chemical Properties,Uses,Production

Chemical Properties

White crystalline powder

Uses

It is used in organic syntheses and as pharmaceutical intermediates. The best results were obtained with lactams that could be introduced on the 6-bromoimidazo[1,2-a]pyridine. 1,2-dihydro-5-imidazo [1,2-a]pyridin-6-yl-6-methyl-2-oxo-3-pyridinecarbonitrile hydrochloride monohydrate 6 was synthesized in 5 steps from 6-bromoimidazo[1,2-a] pyridine using [2- 14 C] cyanoacetamide as the source of the radiolabel.

Synthesis

Chloroacetaldehyde

107-20-0

2-Amino-5-bromopyridine

1072-97-5

6-Bromoimidazo[1,2-a]pyridine

6188-23-4

(1) Preparation of 6-bromoimidazo[1,2-a]pyridine (4): 2.00 g of 2-amino-5-bromopyridine (3) was dissolved in 35 mL of ethanol, and 2.52 mL of 6.1 mol/L aqueous chloroacetaldehyde solution was added. The reaction mixture was heated to reflux for 3 hours. After completion of the reaction, the reaction mixture was concentrated and saturated aqueous NaHCO3 solution was added to the residue and extracted with ethyl acetate. After conventional post-treatment, 2.30 g of 6-bromoimidazo[1,2-a]pyridine was obtained as a brown powder (yield: 100%).LCMS (ESI) m/z (M + H)+: 368.93.

References

[1] Patent: US2011/98471, 2011, A1. Location in patent: Page/Page column 56
[2] Patent: US2014/134133, 2014, A1. Location in patent: Paragraph 0399
[3] Patent: WO2012/116237, 2012, A2. Location in patent: Page/Page column 118
[4] Patent: US2015/320727, 2015, A1. Location in patent: Paragraph 0553; 0554
[5] Patent: WO2008/14219, 2008, A2. Location in patent: Page/Page column 44-45

6-Bromoimidazo[1,2-a]pyridine synthesis

1072-97-5
2032-35-1
6188-23-4
Synthesis of 6-Bromoimidazo[1,2-a]pyridine from 2-Amino-5-bromopyridine and Bromoacetaldehyde diethyl acetal

6-Bromoimidazo[1,2-a]pyridine Preparation Products And Raw materials

Raw materials

Chloroacetaldehyde dimethyl acetal 5-Amino-2-bromopyridine 2-Amino-5-bromopyridine Sodium bicarbonate Chloroacetaldehyde
Chloroacetaldehyde diethyl acetal Bromoacetaldehyde diethyl acetal

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Preparation Products

6-Bromoimidazo[1,2-a]pyridine Suppliers

Global( 277)Suppliers
Supplier Tel Email Country ProdList Advantage
Jinan Sanyuan Chemical Co. LTD 18615587029 3382711390@qq.com China 333 58
Beijing FaMu RuiSi Pharmaceuticals Co.,Ltd 18901358086 pharma_reese@126.com China 48 57
Mashilabs (Shanghai) Co.,Ltd. 19916721580 mafarm@126.com China 4538 58
Jinan Guoding Pharmaceutical Technology Co., Ltd. 053167801621 15665775653 sales@guodingpharma.com China 479 58
Henan Aosman Biotechnology Co., LTD 13761588971 17719817155 2366079749@qq.com China 3009 58
Tongchuang Pharma(Suzhou). Co., Ltd. 0512-63263366 18912765016 tongtf110@sina.com China 984 62
Jinan Xinwei Pharmaceutical Technology Co., LTD 18354101831 13356699551 2067831699@qq.com China 100 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55
Supplier Advantage
Jinan Sanyuan Chemical Co. LTD 58
Beijing FaMu RuiSi Pharmaceuticals Co.,Ltd 57
Mashilabs (Shanghai) Co.,Ltd. 58
Jinan Guoding Pharmaceutical Technology Co., Ltd. 58
Henan Aosman Biotechnology Co., LTD 58
Tongchuang Pharma(Suzhou). Co., Ltd. 62
Jinan Xinwei Pharmaceutical Technology Co., LTD 58
J & K SCIENTIFIC LTD. 76
Alfa Aesar 84
Beijing HwrkChemical Technology Co., Ltd 55

View Lastest Price from 6-Bromoimidazo[1,2-a]pyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-Bromoimidazo[1,2-a]pyridine pictures 2026-09-11 6-Bromoimidazo[1,2-a]pyridine
6188-23-4
 $12.00-217.00 25g 0.98 25kg Shanghai UCHEM Inc.
6-Bromoimidazo[1,2-a]pyridine pictures 2026-08-20 6-Bromoimidazo[1,2-a]pyridine
6188-23-4
 $1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
6-Bromoimidazo[1,2-a]pyridine pictures 2025-04-04 6-Bromoimidazo[1,2-a]pyridine
6188-23-4
 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.

6-Bromoimidazo[1,2-a]pyridine Spectrum

6-Bromoimidazo[1,2-a]pyridine(6188-23-4)1HNMR6-Bromoimidazo[1,2-a]pyridine(6188-23-4)FT-IR

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BUTTPARK 154\50-43 6-BROMOIMIDAZO[1,2-A]PYRIDINE 6-BROMO-INIDAZO[1,2-A]-PYRIDINE 6- BROMINE IMIDAZOLYL [ 1,2-A ] PYRIDINE 6-Bromoimidazo[1,2-a]pyri... 6-BroMoiMidazolo[1,2-a]pyridine IMidazo[1,2-a]pyridine, 6-broMo- 6-BroMo IMidazole[1,2-a]Pyridine 6-Bromoimidazo[1,2-a]pyridine ISO 9001：2015 REACH 6-Bromoimidazo[1.2-alpyridine 6-Bromoimidazo[1,2-a]pyridine 6188-23-4 Heterocycle-Pyridine series CHIRAL CHEMICALS Building Blocks Imidazo[x,x-y]pyridine blocks Bromides Imidazoles Pyridines