1-Hexadecylpyridinium bromide
- CAS No.
- 140-72-7
- Chemical Name:
- 1-Hexadecylpyridinium bromide
- Synonyms
- CETYLPYRIDINIUM BROMIDE;HEXADECYLPYRIDINIUM BROMIDE;Hexadecylpyridinium Bromide Hydrate;bromocet;1-Hexadecylpyridinium;Cetylpyridine bromide;hexadecylpyridine bromide;N-HEXADECYLPYRIDINIUM BROMIDE;tspb;cetasol
- CBNumber:
- CB0322113
- Molecular Formula:
- C21H38BrN
- Molecular Weight:
- 384.44
- MDL Number:
- MFCD00011988
- MOL File:
- 140-72-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 63-69 °C |
|---|---|
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | soluble in Chloroform,Methanol,Acetone,Ethanol |
| form | powder to crystal |
| color | White to Almost white |
| Water Solubility | 5 g/L (20 ºC) |
| BRN | 3778948 |
| InChI | InChI=1S/C21H38N.BrH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19-22-20-17-15-18-21-22;/h15,17-18,20-21H,2-14,16,19H2,1H3;1H/q+1;/p-1 |
| InChIKey | DVBJBNKEBPCGSY-UHFFFAOYSA-M |
| SMILES | [N+]1(CCCCCCCCCCCCCCCC)C=CC=CC=1.[Br-] |
| LogP | 1.699 (est) |
| CAS DataBase Reference | 140-72-7(CAS DataBase Reference) |
| FDA UNII | O77BKZ14DE |
| EPA Substance Registry System | Cetylpyridinium bromide (140-72-7) |
| UNSPSC Code | 12352005 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H315-H319-H330-H335-H413 | |||||||||
| Precautionary statements | P260-P273-P301+P312-P302+P352-P304+P340+P310-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | T+,Xi,Xn | |||||||||
| Risk Statements | 22-26-36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-28-36/37-45-36/37/39-22-36 | |||||||||
| RIDADR | 2811 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UU4848000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29333999 | |||||||||
| Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
|||||||||
| Hazard Classifications | Acute Tox. 2 Inhalation Acute Tox. 4 Oral Aquatic Acute 1 Eye Dam. 1 Skin Irrit. 2 STOT SE 3 |
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| Hazardous Substances Data | 140-72-7(Hazardous Substances Data) | |||||||||
| Toxicity | mouse,LD50,unreported,126mg/kg (126mg/kg),Pharmazie. Vol. 40, Pg. 273, 1985. | |||||||||
| NFPA 704 |
|
1-Hexadecylpyridinium bromide price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 52340 | Hexadecylpyridinium bromide ≥97.0% | 140-72-7 | 100g | $106 | 2026-04-30 | Buy |
| TCI Chemical | H0162 | Hexadecylpyridinium Bromide Hydrate >96.0%(HPLC)(T) | 140-72-7 | 25g | $23 | 2026-04-30 | Buy |
| TCI Chemical | H0162 | Hexadecylpyridinium Bromide Hydrate >96.0%(HPLC)(T) | 140-72-7 | 500g | $173 | 2026-04-30 | Buy |
| Biosynth | FH37372 | Hexadecyl pyridinium bromide | 140-72-7 | 250g | $325 | 2026-06-04 | Buy |
| Biosynth | FH37372 | Hexadecyl pyridinium bromide | 140-72-7 | 1000g | $780 | 2026-06-04 | Buy |
1-Hexadecylpyridinium bromide Chemical Properties, Uses, Production
Description
1-Hexadecylpyridinium bromide is a cationic surfactant capable of bactericidal activity and has been used for ion exchange. As a bactericidal agent, it reduces the surface tension between pathogenic membranes and their environments. This interaction disrupts membrane integrity and osmoregulation, leading to cell lysis. It has also been shown to quickly and efficiently remove metal ions from solutions. The compound removes cations from the solution through a cation/surfactant complex, which precipitates from an aqueous phase into an organic phase and can subsequently be extracted. It is an effective ion exchange agent for extracting DNA and proteins.
Chemical Properties
white to cream coloured powder
Uses
Hexadecylpyridinium bromide (HDPB) is a biochemical assay reagent.
Definition
ChEBI: A pyridinium salt that has N-hexadecylpyridinium as the cation and bromide as the anion.
Synthesis
110-86-1
112-82-3
140-72-7
General method: 1-bromohexadecane (0.01 mol) and pyridine (0.011 mol) were added sequentially to 25 mL of anhydrous acetonitrile and heated to reflux for 24 hours. Upon completion of the reaction, the solvent was removed by evaporation, the residue was co-evaporated with benzene to remove residual water, and finally the N-hexadecyl pyridine bromide salt was recrystallized from acetone.
References
[1] Molecules, 2010, vol. 15, # 3, p. 1967 - 1972
[2] Green Chemistry, 2009, vol. 11, # 1, p. 83 - 90
[3] European Journal of Medicinal Chemistry, 2013, vol. 66, p. 46 - 55
[4] Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1952, vol. 291, p. 1,4
[5] Journal of the American Pharmaceutical Association (1912-1977), 1942, vol. 31, p. 51
1-Hexadecylpyridinium bromide Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beijing Minruida Technology Co., Ltd. | 010-82387566 | sales@mreda.com.cn | China | 19323 | 58 |
| Shanghai Yuanyuan Biotechnology Co. , Ltd. | 021-58796960 13585883992 | herochem021@163.com | China | 31 | 58 |
| LANZHOU DAYUAN NEW MATERIAL TECHNOLOGY CO.,LTD | 13992067598 | wpthisage@163.com | China | 5 | 58 |
| Beijing Jingtu Hengsheng Commerce&Trade Co.,Ltd. | 00-13911456598 13911456598 | 13911456598@163.cn | China | 2529 | 58 |
| Jinan Dexinjia Bio&Tech Co., Ltd | 0531-82375880 15098789112 | 3845379039@qq.com | China | 1458 | 58 |
| Tianshui YiYao Chemical Co., Ltd. | 0938-0938-8493022 15379872136 | xiaoshi079@163.com | China | 2030 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
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View Latest Price from 1-Hexadecylpyridinium bromide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-15 | 1-Hexadecylpyridinium bromide
140-72-7
|
1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-09-02 | 1-Hexadecylpyridiniumbromide
140-72-7
|
$5.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-08-20 | 1-Hexadecylpyridinium bromide
140-72-7
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited |
-
- 1-Hexadecylpyridinium bromide
140-72-7
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 1-Hexadecylpyridiniumbromide
140-72-7
- $5.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 1-Hexadecylpyridinium bromide
140-72-7
- $1.10
- 99.00%
- Dideu Industries Group Limited
