4-Nitrocinnamic acid
- CAS No.
- 619-89-6
- Chemical Name:
- 4-Nitrocinnamic acid
- Synonyms
- (E)-3-(4-nitrophenyl)acrylic acid;3-(4-Nitrophenyl)acrylic acid;NSC 2067;NSC 638142;AKOS B004090;4-Nitrociamic acid;RARECHEM BK HC P253;p-nitro-cinnamicaci;p-Nitrocinnamic acid;OTAVA-BB BB7020401717
- CBNumber:
- CB0142898
- Molecular Formula:
- C9H7NO4
- Molecular Weight:
- 193.16
- MDL Number:
- MFCD00007381
- MOL File:
- 619-89-6.mol
- MSDS File:
- SDS
| Melting point | 200-202 °C(lit.) |
|---|---|
| Boiling point | 329.36°C (rough estimate) |
| Density | 1.4058 (rough estimate) |
| refractive index | 1.5200 (estimate) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | DMSO |
| form | Solid |
| pka | 4.07±0.10(Predicted) |
| color | Yellow |
| Water Solubility | insoluble |
| InChI | InChI=1S/C9H7NO4/c11-9(12)6-3-7-1-4-8(5-2-7)10(13)14/h1-6H,(H,11,12) |
| InChIKey | XMMRNCHTDONGRJ-ZZXKWVIFSA-N |
| SMILES | C(O)(=O)C=CC1=CC=C([N+]([O-])=O)C=C1 |
| CAS DataBase Reference | 619-89-6(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| NIST Chemistry Reference | trans-4-Nitrocinnmic acid(619-89-6) |
| EPA Substance Registry System | 2-Propenoic acid, 3-(4-nitrophenyl)- (619-89-6) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | GE0352000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29163990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
4-Nitrocinnamic acid price More Price(57)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | N16428 | 4-Nitrocinnamic acid, predominantly trans 97% | 619-89-6 | 25g | $90 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.18563 | 4′-Nitrocinnamic acid for synthesis | 619-89-6 | 25 g | $120 | 2026-04-30 | Buy |
| TCI Chemical | N0355 | 4-Nitrocinnamic Acid >99.0%(T) | 619-89-6 | 10g | $69 | 2026-04-30 | Buy |
| TCI Chemical | N0355 | 4-Nitrocinnamic Acid >99.0%(T) | 619-89-6 | 25g | $137 | 2026-04-30 | Buy |
| TRC | TRC-N495815-50G | 4-Nitrocinnamic Acid | 619-89-6 | 50g | $91 | 2026-06-03 | Buy |
4-Nitrocinnamic acid Chemical Properties, Uses, Production
Chemical Properties
Yellow needle-like crystals. Melting point 289°C. Insoluble in water.
Occurrence
The heartwood of Cassia garrettiana.
Uses
4-Nitrocinnamic Acid (cas# 619-89-6) is a compound useful in organic synthesis.
Preparation
Synthesis of 4-nitrocinnamic acid: 4-nitro-trans-cinnamonitrile, concentrated hydrochloric acid and water were heated and refluxed for 8h, and left standing overnight. The precipitate was filtered out, dissolved in hot 30% sodium hydroxide solution, the insoluble matter was filtered off, the filtrate was acidified with 50% sulfuric acid to precipitate precipitation, the crude product was filtered, and recrystallized with ethanol to obtain 4-nitrocinnamic acid.
Biological Activity
4-Nitrocinnamic acid is a photosensitive compound that has inhibitory effects on tyrosinase.
4-Nitrocinnamic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan lenmaike Industrial Co., Ltd. | 027-83916065 18627177625 | 3561583191@qq.com | China | 48 | 58 |
| Creasyn Finechem(Tianjin) Co., Ltd. | 022-83946278 13820372920 | sales@creasyn.com | China | 968 | 68 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
View Latest Price from 4-Nitrocinnamic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-03-20 | 4-Nitrocinnamic acid
619-89-6
|
$9.80 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
![]() |
2025-05-26 | 4-Nitrocinnamic acid
619-89-6
|
$8.00 | 1kg | 0.99 | 1000000 | Hebei Fengjia New Material Co., Ltd | |
![]() |
2025-04-04 | 4-Nitrocinnamic acid
619-89-6
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
-

- 4-Nitrocinnamic acid
619-89-6
- $9.80
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-

- 4-Nitrocinnamic acid
619-89-6
- $8.00
- 0.99
- Hebei Fengjia New Material Co., Ltd
-

- 4-Nitrocinnamic acid
619-89-6
- 98%
- Henan Aochuang Chemical Co.,Ltd.





