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4-Nitrocinnamic acid

CAS No.
619-89-6
Chemical Name:
4-Nitrocinnamic acid
Synonyms
(E)-3-(4-nitrophenyl)acrylic acid;3-(4-Nitrophenyl)acrylic acid;NSC 2067;NSC 638142;AKOS B004090;4-Nitrociamic acid;RARECHEM BK HC P253;p-nitro-cinnamicaci;p-Nitrocinnamic acid;OTAVA-BB BB7020401717
CBNumber:
CB0142898
Molecular Formula:
C9H7NO4
Molecular Weight:
193.16
MDL Number:
MFCD00007381
MOL File:
619-89-6.mol
MSDS File:
SDS
Last updated:2026-05-27 17:19:10

4-Nitrocinnamic acid Properties

Melting point 200-202 °C(lit.)
Boiling point 329.36°C (rough estimate)
Density 1.4058 (rough estimate)
refractive index 1.5200 (estimate)
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility DMSO
form Solid
pka 4.07±0.10(Predicted)
color Yellow
Water Solubility insoluble
InChI InChI=1S/C9H7NO4/c11-9(12)6-3-7-1-4-8(5-2-7)10(13)14/h1-6H,(H,11,12)
InChIKey XMMRNCHTDONGRJ-ZZXKWVIFSA-N
SMILES C(O)(=O)C=CC1=CC=C([N+]([O-])=O)C=C1
CAS DataBase Reference 619-89-6(CAS DataBase Reference)
EWG's Food Scores 1
NIST Chemistry Reference trans-4-Nitrocinnmic acid(619-89-6)
EPA Substance Registry System 2-Propenoic acid, 3-(4-nitrophenyl)- (619-89-6)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-24/25
WGK Germany  3
RTECS  GE0352000
TSCA  TSCA listed
HazardClass  IRRITANT
HS Code  29163990
Storage Class 11 - Combustible Solids
NFPA 704
0
2 0

4-Nitrocinnamic acid price More Price(57)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich N16428 4-Nitrocinnamic acid, predominantly trans 97% 619-89-6 25g $90 2026-04-30 Buy
Sigma-Aldrich 8.18563 4′-Nitrocinnamic acid for synthesis 619-89-6 25 g $120 2026-04-30 Buy
TCI Chemical N0355 4-Nitrocinnamic Acid >99.0%(T) 619-89-6 10g $69 2026-04-30 Buy
TCI Chemical N0355 4-Nitrocinnamic Acid >99.0%(T) 619-89-6 25g $137 2026-04-30 Buy
TRC TRC-N495815-50G 4-Nitrocinnamic Acid 619-89-6 50g $91 2026-06-03 Buy
Product number Packaging Price Buy
N16428 25g $90 Buy
8.18563 25 g $120 Buy
N0355 10g $69 Buy
N0355 25g $137 Buy
TRC-N495815-50G 50g $91 Buy

4-Nitrocinnamic acid Chemical Properties, Uses, Production

Chemical Properties

Yellow needle-like crystals. Melting point 289°C. Insoluble in water.

Occurrence

The heartwood of Cassia garrettiana.

Uses

4-Nitrocinnamic Acid (cas# 619-89-6) is a compound useful in organic synthesis.

Preparation

Synthesis of 4-nitrocinnamic acid: 4-nitro-trans-cinnamonitrile, concentrated hydrochloric acid and water were heated and refluxed for 8h, and left standing overnight. The precipitate was filtered out, dissolved in hot 30% sodium hydroxide solution, the insoluble matter was filtered off, the filtrate was acidified with 50% sulfuric acid to precipitate precipitation, the crude product was filtered, and recrystallized with ethanol to obtain 4-nitrocinnamic acid.

Biological Activity

4-Nitrocinnamic acid is a photosensitive compound that has inhibitory effects on tyrosinase.

4-Nitrocinnamic acid Preparation Products And Raw materials

Global Suppliers ( 290)
Supplier Tel Email Country ProdList Advantage
Wuhan lenmaike Industrial Co., Ltd. 027-83916065 18627177625 3561583191@qq.com China 48 58
Creasyn Finechem(Tianjin) Co., Ltd. 022-83946278 13820372920 sales@creasyn.com China 968 68
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64

View Latest Price from 4-Nitrocinnamic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Nitrocinnamic acid pictures 2026-03-20 4-Nitrocinnamic acid
619-89-6
$9.80 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
4-Nitrocinnamic acid pictures 2025-05-26 4-Nitrocinnamic acid
619-89-6
$8.00 1kg 0.99 1000000 Hebei Fengjia New Material Co., Ltd
4-Nitrocinnamic acid pictures 2025-04-04 4-Nitrocinnamic acid
619-89-6
1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
RARECHEM BK HC P253 OTAVA-BB BB7020401717 TRANS-3-(3-NITROPHENYL)PROPENOIC ACID TRANS-3-NITROCINNAMIC ACID 3-(3-NITROPHENYL)ACRYLIC ACID AKOS B004090 LABOTEST-BB LT00005570 (2E)-3-(4-Nitrophenyl)-2-propenoic acid 2-Propenoic acid, 3-(4-nitrophenyl)- NSC 2067 NSC 638142 p-NitrocinnaMic acid, 98%, predoMinantly trans 3-(4-Nitrophenyl)acrylic acid, 3-(4-Nitrophenyl)prop-2-enoic acid 4-Nitrocinnamic acid, predominantly trans 97% trans-4-Nitrocinnmic acid (E)-3-(4-nitrophenyl)prop-2-enoic acid 2-Propenoic acid, 3-(4-nitrophen N-hydroxy-4-[(E)-3-hydroxy-3-keto-prop-1-enyl]benzeneamine oxide N-hydroxy-4-[(E)-3-hydroxy-3-oxo-prop-1-enyl]benzeneamine oxide N-hydroxy-4-[(E)-3-hydroxy-3-oxoprop-1-enyl]benzeneamine oxide (E)-3-(4-nitrophenyl)-2-propenoate 3-(4-nitrophenyl)-2-propenoicaci Cinnamic acid, p-nitro- Para-nitrocinnamic acid p-nitro-cinnamicaci 3-p-Nitrophenylacrylic acid 4-Nitrocinnamic acid,predominantly trans 4-NITROCINNAMIC ACID, 97%, PREDOMINANTLY TRANS p-Nitrocinnamic acid, predominantly trans, 97% 4-Nitrocinnamic acid 98% 4-NITROCINNAMIC ACID 99+% 3-(4-Nitrophenyl)-2-propenoic acid p-Nitrocinnamic acid (E)-3-(4-nitrophenyl)-2-propenoic acid 4-Nitrobenzeneacrylic acid (2E)-3-(4-nitrophenyl)acrylic acid p-Nitrocinnamic acid,97%,predominantly trans 4-Nitrociamic acid (2E)-3-(4-nitrophenyl)prop-2-enoic acid 4-Nitrocinnamic acid, 98+% 4-NitrocinnamicAcid> 4-Nitrocinnamic acid USP/EP/BP 4-Nitrocinnamic acid p-nitro-cinnamicaci,RARECHEM BK HC P253,4-nitrocinnamic acide,p-Nitrocinnamic acid 4-Nitrocinnamic acid, predominantly trans (E)-3-(4-nitrophenyl)acrylic acid 3-(4-Nitrophenyl)acrylic acid 619-89-6 Building Blocks Carbonyl Compounds Carboxylic Acids C9 Organic Building Blocks Aromatics Aromatics Compounds Heterocyclic Compounds Cinnamic acid FINE Chemical & INTERMEDIATES Aromatic Cinnamic Acids, Esters and Derivatives