6-bromocinnoline
- CAS No.
- 318276-72-1
- Chemical Name:
- 6-bromocinnoline
- Synonyms
- 6-bromocinnoline;Cinnoline, 6-bromo-
- CBNumber:
- CB01458264
- Molecular Formula:
- C8H5BrN2
- Molecular Weight:
- 209.04
- MDL Number:
- MFCD09834644
- MOL File:
- 318276-72-1.mol
| Melting point | 129-130 °C |
|---|---|
| Boiling point | 325.0±34.0 °C(Predicted) |
| Density | 1.656±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 1.75±0.10(Predicted) |
| Appearance | black powder |
| CAS DataBase Reference | 318276-72-1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501 |
6-bromocinnoline price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS14099 | 6-Bromocinnoline 95% | 318276-72-1 | 250mg | $175 | 2026-06-04 | Buy |
| Activate Scientific | AS14099 | 6-Bromocinnoline 95% | 318276-72-1 | 1g | $431 | 2026-06-04 | Buy |
| Activate Scientific | AS14099 | 6-Bromocinnoline 95% | 318276-72-1 | 5g | $1789 | 2026-06-04 | Buy |
| Matrix Scientific | 298840 | 6-Bromocinnoline | 318276-72-1 | 100.00mg | $76 | 2026-05-19 | Buy |
| Matrix Scientific | 298840 | 6-Bromocinnoline | 318276-72-1 | 250.00mg | $95 | 2026-05-19 | Buy |
6-bromocinnoline Chemical Properties, Uses, Production
Synthesis
552330-88-8
318276-72-1
Synthesis of Example 34F 6-Bromocinnoline: Example 34E (3.5 g, 14 mmol) was dissolved in water (50 mL) and heated to reflux. Subsequently, a solution of CuSO4 (2.8 g, 17.5 mmol) in water (20 mL) was added slowly dropwise to the reaction system and kept at reflux for 2 hours. After completion of the reaction, the reaction was cooled to room temperature and the pH was adjusted with saturated aqueous NaHCO3 solution to 7. The reaction mixture was extracted with ethyl acetate (2 x 25 mL), the organic phases were combined and concentrated. The crude product was purified by fast column chromatography on silica gel with the eluent being a 1:1 hexane/ethyl acetate solvent mixture to give the final target product 6-bromocinnoline (0.7 g, 24% yield).
References
[1] Bioorganic and Medicinal Chemistry, 2006, vol. 14, # 20, p. 6832 - 6846
[2] Patent: US2003/187026, 2003, A1
[3] Patent: US2003/199511, 2003, A1. Location in patent: Page/Page column 27
[4] Journal of the Chemical Society, 1950, p. 392,395
6-bromocinnoline Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| shanghai honghe yiyao | 18352536981 | 653603901@qq.com | China | 589 | 58 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| China Langchem Inc. | 0086-21-58956006 | China | 7798 | 57 | |
| shanghai cooperpharm co.,LTD . | +86-021-58975553 | sales@cooperpharm.com | China | 1210 | 56 |
| Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd. | +86-28-85122536 85324413 | market@astatech.cn | China | 8016 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai HuanChuan Industry Co.,Ltd. | 021-61478794 | sales@hcshhai.com | China | 9781 | 50 |
| JW & Y Pharmlab Co., Ltd. | 021-64340559 | xinyu_shi@jwypharmlab.com.cn | China | 11999 | 58 |
| Shanghai Chiral bio-compound co., Ltd. | 021-5068 3667/17749785980/1029026415; 17749785980 | 1029026415@qq.com | China | 4501 | 58 |
