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ChemicalBook >> CAS DataBase List >>1H-Pyrazole-4-carboxamide, 5-amino-N-[(2R)-2-[[(2,6-dichlorobenzoyl)ethylamino]methyl]-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)-

1H-Pyrazole-4-carboxamide, 5-amino-N-[(2R)-2-[[(2,6-dichlorobenzoyl)ethylamino]methyl]-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)-

1H-Pyrazole-4-carboxamide, 5-amino-N-[(2R)-2-[[(2,6-dichlorobenzoyl)ethylamino]methyl]-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)- Structure
1H-Pyrazole-4-carboxamide, 5-amino-N-[(2R)-2-[[(2,6-dichlorobenzoyl)ethylamino]methyl]-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)- structure
CAS No.
1094607-80-3
Chemical Name:
1H-Pyrazole-4-carboxamide, 5-amino-N-[(2R)-2-[[(2,6-dichlorobenzoyl)ethylamino]methyl]-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)-
Synonyms
(R)-GSK866;1H-Pyrazole-4-carboxamide, 5-amino-N-[(2R)-2-[[(2,6-dichlorobenzoyl)ethylamino]methyl]-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)-
CBNumber:
CB014686096
Molecular Formula:
C23H21Cl2F4N5O3
Molecular Weight:
562.34
MDL Number:
MOL File:
1094607-80-3.mol
MSDS File:
SDS
Last updated:2025-04-18 09:51:25
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1H-Pyrazole-4-carboxamide, 5-amino-N-[(2R)-2-[[(2,6-dichlorobenzoyl)ethylamino]methyl]-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)- Properties

Boiling point 761.3±60.0 °C(predicted)
Density 1.49±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka 9.13±0.46(predicted)
form Solid
color White to off-white

1H-Pyrazole-4-carboxamide, 5-amino-N-[(2R)-2-[[(2,6-dichlorobenzoyl)ethylamino]methyl]-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-1013552 (R)-GSK866 98.0% 1094607-80-3 5mg $575 2026-06-04 Buy
ChemScene CS-1013552 (R)-GSK866 98.0% 1094607-80-3 10mg $921 2026-06-04 Buy
ChemScene CS-1013552 (R)-GSK866 98.0% 1094607-80-3 25mg $1842 2026-06-04 Buy
Arctom HY-157294A (R)-GSK866 98.0% 1094607-80-3 5mg $505 2026-05-26 Buy
Arctom HY-157294A (R)-GSK866 98.0% 1094607-80-3 10mg $808 2026-05-26 Buy
Product number Packaging Price Buy
CS-1013552 5mg $575 Buy
CS-1013552 10mg $921 Buy
CS-1013552 25mg $1842 Buy
HY-157294A 5mg $505 Buy
HY-157294A 10mg $808 Buy

1H-Pyrazole-4-carboxamide, 5-amino-N-[(2R)-2-[[(2,6-dichlorobenzoyl)ethylamino]methyl]-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)- Chemical Properties, Uses, Production

Uses

(R)-GSK866 is the (R)-enantiomer of GSK866 (HY-157294). GSK866 is a selective agonist for glucocorticoid receptor with an IC50 of 4.6 nM[1].

References

[1] Chandra S Chirumamilla, et al. Selective Glucocorticoid Receptor Properties of GSK866 Analogs with Cysteine Reactive Warheads. Front Immunol. 2017 Nov 1:8:1324. DOI:10.3389/fimmu.2017.01324

1H-Pyrazole-4-carboxamide, 5-amino-N-[(2R)-2-[[(2,6-dichlorobenzoyl)ethylamino]methyl]-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Pyrazole-4-carboxamide, 5-amino-N-[(2R)-2-[[(2,6-dichlorobenzoyl)ethylamino]methyl]-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)- Suppliers

Global Suppliers ( 3)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
TargetMol Chemicals Inc. 58

1094607-80-3 (1H-Pyrazole-4-carboxamide, 5-amino-N-[(2R)-2-[[(2,6-dichlorobenzoyl)ethylamino]methyl]-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)-) Related Search:

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1H-Pyrazole-4-carboxamide, 5-amino-N-[(2R)-2-[[(2,6-dichlorobenzoyl)ethylamino]methyl]-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)- (R)-GSK866 1094607-80-3