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2-Bromo-4-pyridine acetic acid

2-Bromo-4-pyridine acetic acid Structure
2-Bromo-4-pyridine acetic acid structure
CAS No.
183483-29-6
Chemical Name:
2-Bromo-4-pyridine acetic acid
Synonyms
2-Bromopyridine-4-acetic acid;2-Bromo-4-pyridine acetic acid;4-Pyridineacetic acid, 2-bromo-;2-(2-bromo-4-pyridyl)acetic acid
CBNumber:
CB0147404
Molecular Formula:
C7H6BrNO2
Molecular Weight:
216.03
MDL Number:
MFCD07367935
MOL File:
183483-29-6.mol
MSDS File:
SDS
Last updated:2026-09-12 18:44:32
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2-Bromo-4-pyridine acetic acid Properties

Melting point 145-150°C
Boiling point 374.1±27.0 °C(Predicted)
Density 1.710±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form solid
pka 3.66±0.10(Predicted)
Appearance Off-white to brown Solid
InChI InChI=1S/C7H6BrNO2/c8-6-3-5(1-2-9-6)4-7(10)11/h1-3H,4H2,(H,10,11)
InChIKey SJFRXYCVLZOAEU-UHFFFAOYSA-N
SMILES C1(Br)=NC=CC(CC(O)=O)=C1
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22
WGK Germany  3
HS Code  2933399990

2-Bromo-4-pyridine acetic acid price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 775967 2-Bromopyridine-4-acetic acid 97% 183483-29-6 1g $120 2023-06-20 Buy
Biosynth IHA48329 2-Bromopyridine-4-acetic acid 183483-29-6 2.5g $324.5 2026-06-04 Buy
Activate Scientific AS117963 2-(2-Bromopyridin-4-yl)acetic acid 95% 183483-29-6 1g $65 2026-06-04 Buy
Activate Scientific AS117963 2-(2-Bromopyridin-4-yl)acetic acid 95% 183483-29-6 5g $324 2026-06-04 Buy
Matrix Scientific 309385 2-(2-Bromopyridin-4-yl)acetic acid 183483-29-6 1.00g $58 2026-05-19 Buy
Product number Packaging Price Buy
775967 1g $120 Buy
IHA48329 2.5g $324.5 Buy
AS117963 1g $65 Buy
AS117963 5g $324 Buy
309385 1.00g $58 Buy

2-Bromo-4-pyridine acetic acid Chemical Properties, Uses, Production

Synthesis

(2-bromo-pyridin-4-yl)-acetic acid ethyl ester

1256337-24-2

2-BROMO-4-PYRIDINE ACETIC ACID

183483-29-6

General procedure for the synthesis of 2-(2-bromopyridin-4-yl)acetic acid from ethyl 2-(2-bromopyridin-4-yl)acetate: to a mixture of THF (5 mL), MeOH (10 mL) and water (5 mL) containing ethyl 2-(2-bromopyridin-4-yl)acetate (1.00 g, 4.10 mmol) was added lithium hydroxide (294 mg, 12.3 mmol). The reaction mixture was stirred at 20 °C for 10 min. Upon completion of the reaction, THF and MeOH were removed by vacuum concentration and the residue was diluted with 10 mL of water. Subsequently, the aqueous phase was acidified with 2N HCl solution to pH = 2. The mixture was filtered, the filter cake was collected and dried under vacuum to afford the target product 2-(2-bromopyridin-4-yl)acetic acid (850 mg, 90% yield) as a white solid.LCMS analysis resulted in (ES+) m/z (M+H)+ = 217.9 and retention time tR = 0.539 min.

References

[1] Patent: WO2018/106636, 2018, A1. Location in patent: Paragraph 00242

2-Bromo-4-pyridine acetic acid Preparation Products And Raw materials

Raw materials

(2-bromo-pyridin-4-yl)-acetic acid ethyl ester Water Lithium hydroxide Tetrahydrofuran Methanol

Preparation Products

2-Bromo-4-pyridine acetic acid Suppliers

Global Suppliers ( 56)
Supplier Tel Email Country ProdList Advantage
Wuxi KaideRui Pharmaceutical Technology Co., Ltd 19906241957 1557216087@qq.com China 1853 55
SynAsst Chemical. 021-60343070 China 12731 55
Wuhan Kaymke Chemical Co., Ltd., 027-87342388 18086026008 sales@kaymke.com China 3538 55
Yancheng Orgunion Pharmaceutical Sci & Tech Co., Ltd. 0515-89701588 13770166955 orgunion@orgunion.com China 620 55
Tianjin Anhao Biological Technology Co., Ltd. sales@ahpharmatech.com China 5734 55
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Shanghai DongYang Biotechnology Co., Ltd. 18657622632 chemsharker@126.com China 371 55
Yancheng KangdiSen Pharmaceutical Co., Ltd. 13812573443;18052965989 tongbenwan22@163.com China 1975 55
Shanghai Chaolan Chemical Technology Center QQ：65489617 13301690235 Sales@ATKchemical.com China 9699 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Supplier Advantage
Wuxi KaideRui Pharmaceutical Technology Co., Ltd 55
SynAsst Chemical. 55
Wuhan Kaymke Chemical Co., Ltd., 55
Yancheng Orgunion Pharmaceutical Sci & Tech Co., Ltd. 55
Tianjin Anhao Biological Technology Co., Ltd. 55
Sigma-Aldrich 80
Shanghai DongYang Biotechnology Co., Ltd. 55
Yancheng KangdiSen Pharmaceutical Co., Ltd. 55
Shanghai Chaolan Chemical Technology Center 58
Amadis Chemical Company Limited 58

2-Bromo-4-pyridine acetic acid Spectrum

2-BROMO-4-PYRIDINE ACETIC ACID(183483-29-6)1HNMR

183483-29-6 (2-Bromo-4-pyridine acetic acid) Related Search:

ethyl 2-(3-bromopyridin-4-yl)acetate 2-Bromo-4-ethylpyridine 2-Bromo-4-pyridine acetic acid 2,2'-Bipyridine-5,5'-dicarboxylic acid (2-BroMo-pyridin-4-yl)-acetic acid Methyl ester
2-(2-Bromopyridin-4-yl)acetonitrile

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2-Bromopyridine-4-acetic acid 4-Pyridineacetic acid, 2-bromo- 2-(2-bromo-4-pyridyl)acetic acid 2-Bromo-4-pyridine acetic acid 183483-29-6