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2-Amino-6-methoxybenzothiazole

2-Amino-6-methoxybenzothiazole Structure
2-Amino-6-methoxybenzothiazole structure
CAS No.
1747-60-0
Chemical Name:
2-Amino-6-methoxybenzothiazole
Synonyms
6-METHOXYBENZO[D]THIAZOL-2-AMINE;AKOS AUF2099;AURORA KA-685;ASISCHEM B88987;AKOS BBS-00005696;TIMTEC-BB SBB003746;IFLAB-BB F1386-0390;2-Amino-6-methoxyben;6-methoxy-2-benzothiazolamin;6-METHOXY-2-BENZOTHIAZOLAMINE
CBNumber:
CB0152684
Molecular Formula:
C8H8N2OS
Molecular Weight:
180.23
MDL Number:
MFCD00005787
MOL File:
1747-60-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-08-26 18:28:42
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2-Amino-6-methoxybenzothiazole Properties

Melting point 165-167 °C (lit.)
Boiling point 240°C
Density 1.2425 (rough estimate)
refractive index 1.5690 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility very slightly in Methanol
pka pK1: 4.50(+1) (25°C)
form Crystalline Powder
color White to beige
Water Solubility <0.1 g/100 mL at 21 ºC
Stability Stable, but may be light sensitive. Incompatible with strong oxidizing agents.
InChI InChI=1S/C8H8N2OS/c1-11-5-2-3-6-7(4-5)12-8(9)10-6/h2-4H,1H3,(H2,9,10)
InChIKey KZHGPDSVHSDCMX-UHFFFAOYSA-N
SMILES S1C2=CC(OC)=CC=C2N=C1N
CAS DataBase Reference 1747-60-0(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII LAT2842YVX
EPA Substance Registry System 2-Amino-6-methoxybenzothiazole (1747-60-0)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38-20/21/22
Safety Statements  26-36
RIDADR  2811
WGK Germany  3
RTECS  DL2100000
TSCA  TSCA listed
HazardClass  IRRITANT
PackingGroup  III
HS Code  29342080
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Toxicity mouse,LD50,intravenous,140mg/kg (140mg/kg),Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 486, 1952.
REACH Registrations Active
NFPA 704
1
2 0

2-Amino-6-methoxybenzothiazole price More Price(77)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical A0715 2-Amino-6-methoxybenzothiazole >98.0%(T) 1747-60-0 25g $21 2026-04-30 Buy
TCI Chemical A0715 2-Amino-6-methoxybenzothiazole >98.0%(T) 1747-60-0 100g $51 2026-04-30 Buy
Usbiological 415347 2-Amino-6-methoxybenzothiazole 1747-60-0 1g $403 2026-06-03 Buy
Usbiological 415347 2-Amino-6-methoxybenzothiazole 1747-60-0 2.5g $658 2026-06-03 Buy
Usbiological 260182 2-Amino-6-methoxybenzothiazole Asreported 1747-60-0 25g $289 2026-06-03 Buy
Product number Packaging Price Buy
A0715 25g $21 Buy
A0715 100g $51 Buy
415347 1g $403 Buy
415347 2.5g $658 Buy
260182 25g $289 Buy

2-Amino-6-methoxybenzothiazole Chemical Properties, Uses, Production

Uses

2-Amino-6-methoxybenzothiazole is an intermediate used to prepare novel series of Schiff bases and 4-thiazolidinones. It is also used in the synthesis of 2-cyano-6-methoxybenzothiazole.

Chemical Properties

off-white to tan-coloured powder

Uses

2-Amino-6-methoxybenzothiazole was used as building block in the syntheses of novel series of Schiff bases and 4-thiazolidinones. It was used in the synthesis of 2-cyano-6-methoxybenzothiazole, key intermediate for the synthesis of firefly luciferin.

General Description

Fine off-white to light tan powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

2-Amino-6-methoxybenzothiazole may be sensitive to exposure to light. 2-Amino-6-methoxybenzothiazole is incompatible with strong oxidizers.

Fire Hazard

Flash point data for 2-Amino-6-methoxybenzothiazole are not available; however, 2-Amino-6-methoxybenzothiazole is probably combustible.

Synthesis

Potassium thiocyanate

333-20-0

p-Anisidine

104-94-9

2-Amino-6-methoxybenzothiazole

1747-60-0

0.1 mole of p-aminoanisole and 0.1 mole of potassium thiocyanate (KCNS) were dissolved in 100 mL of glacial acetic acid (AcOH) and the mixture was cooled and stirred in an ice bath for 10-20 minutes. Subsequently, 0.1 mol of bromine in glacial acetic acid solution was slowly added dropwise, with the rate of dropwise acceleration controlled to maintain the reaction temperature below 10 °C. After the dropwise addition was completed, the reaction mixture was stirred at room temperature for 2-4 hours. After completion of the reaction, the resulting hydrobromide (HBr) salt was separated by filtration, washed with glacial acetic acid and dried. The dried salt was dissolved in hot water and alkalized by adjusting the pH to 11.0 with ammonia solution (NH4OH). The precipitate precipitated was filtered, washed with water and dried to give the target product 2-amino-6-methoxybenzothiazole. The reaction process was monitored by thin layer chromatography (TLC) using toluene: acetone (8:2) as unfolding agent.

References

[1] Synlett, 2012, vol. 23, # 15, p. 2219 - 2222
[2] Synlett, 2009, # 16, p. 2682 - 2684
[3] Heterocyclic Communications, 2018, vol. 24, # 5, p. 255 - 258
[4] Phosphorus, Sulfur and Silicon and the Related Elements, 2008, vol. 183, # 5, p. 1124 - 1133
[5] European Journal of Medicinal Chemistry, 2008, vol. 43, # 5, p. 1114 - 1122

2-Amino-6-methoxybenzothiazole Preparation Products And Raw materials

Raw materials

Industrial hydrochloric acid P-methoxybenzyl thiourea Disulfur dichloride Sodium thiocyanate Congo red paper
Phenolphthalein Water p-Anisidine Aniline 4-Methoxyphenylthiourea

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Preparation Products

BASIC BLUE 41 (C.I. 11105) 6-Methoxy-3-methyl-2(3H)-benzothiazolone hydrazone Basic Blue 162 Catonic Dark Yellow 2RL 2-Amino-6-ethoxybenzothiazole
2-Cyano-6-methoxybenzothiazole BASIC BLUE 41 SUPRACET BRILLIANT RED BD Basic Blue 162 3-(3-amino-3-oxopropyl)-2-[[4-[bis(2-chloroethyl)amino]phenyl]azo]-6-methoxybenzothiazolium chloride
1,2,3,4-Tetrahydro-6-[(6-methoxybenzothiazol-2-yl)azo]benzo[h]quinoline-3,7-diol BASIC YELLOW 19

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2-Amino-6-methoxybenzothiazole Suppliers

Global Suppliers ( 477)
Supplier Tel Email Country ProdList Advantage
Shandong Qianyuan Polymer Material Co. , Ltd. 18678041314 18765609661 2547772582@qq.com China 987 58
Anstar Chemical (Group) Co.,Ltd. 18053179586 export@anstarchemical.com China 698 58
Wuhan Wenjin Chemical Technology Co., Ltd. 13517196568 375665891@qq.com China 500 58
Wuhan Hongde Yuexin Pharmatech Co.,Ltd 027-83850116 18164090116 whhdyxchem123@sina.com China 7411 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Supplier Advantage
Shandong Qianyuan Polymer Material Co. , Ltd. 58
Anstar Chemical (Group) Co.,Ltd. 58
Wuhan Wenjin Chemical Technology Co., Ltd. 58
Wuhan Hongde Yuexin Pharmatech Co.,Ltd 58
J & K SCIENTIFIC LTD. 76
INTATRADE GmbH 66
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Alfa Aesar 84
TAIYUAN RHF CO.,LTD. 56
TCI (Shanghai) Development Co., Ltd. 81

Related Questions

Ask a question
Q:What is the uses and toxicity of 2-Amino-6-methoxybenzothiazole?Zora - Dec 2,2025
A:2-Amino-6-methoxybenzothiazole is used as a building block in the syntheses of novel series of Schiff bases and 4-thiazolidinones. It was also used in the synthesis of 2-cyano-6-methoxybenzothiazole. It has acute oral toxicity and germ cell mutagenicity.

View Latest Price from 2-Amino-6-methoxybenzothiazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Amino-6-methoxybenzothiazole pictures 2026-09-15 2-Amino-6-methoxybenzothiazole
1747-60-0
 1KG 97% 1000 KG Henan Alfa Chemical Co., Ltd
2-Amino-6-methoxybenzothiazole pictures 2026-05-28 2-Amino-6-methoxybenzothiazole
1747-60-0
 $2.00-5.00 1KG 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
2-Amino-6-methoxybenzothiazole pictures 2026-04-27 2-Amino-6-methoxybenzothiazole
1747-60-0
 1kg 98% 100tons Shandong Vital Biotechnology Co., Ltd.

2-Amino-6-methoxybenzothiazole Spectrum

2-Amino-6-methoxybenzothiazole(1747-60-0)MS2-Amino-6-methoxybenzothiazole(1747-60-0)1HNMR2-Amino-6-methoxybenzothiazole(1747-60-0)IR12-Amino-6-methoxybenzothiazole(1747-60-0)IR22-Amino-6-methoxybenzothiazole(1747-60-0)Raman

1747-60-0 (2-Amino-6-methoxybenzothiazole) Related Search:

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2-Amino-6-ethoxybenzothiazole 2-Acetoacetamido-6-ethoxybenzothiazole Basic Blue 54

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2-amino-6-methoxy-benzothiazol 6-methoxy-2-benzothiazolamin TIMTEC-BB SBB003746 2-AMINO-6-METHOXYBENZOTHIAZOLE 2-AMINO-6-METHOXYBENZOTHIOPHENE 2-BENZOTHIAZOLAMINE, 6-METHOXY- AKOS BBS-00005696 AKOS AUF2099 6-METHOXY-BENZOTHIAZOL-2-YLAMINE 6-METHOXY-2-AMINO-BENZOTHIAZOLE 6-METHOXY-2-BENZOTHIAZOLAMINE 2-Amino-6-methoxybenzothizole 2-AMINO-6-METHOXYBENZOTHIAZOLE, TECH. 2-Amino-6-Methoxybenzothiazole98% 6-METHOXY-1,3-BENZOTHIAZOL-2-AMINE 6-METHOXY-1,3-BENZOTHIAZOL-2-YLAMINE IFLAB-BB F1386-0390 AURORA KA-685 ASISCHEM B88987 2-AMINO-6-METHOXY BENZOTHIAZOLE (CHINESE) 2-Benzothiazolamine,6-methoxy-(9CI) 2-Amino-6-methoxybezothiazole 6-METHOXY-2-BENZOTHIAZOLEAMINE 2-Amino-6-methoxy-1,3-benzothiazole 98% 2-Amino-6-methoxy-1,3-benzothiazole 2-Amino-6-methoxybenzothiazole, 90%,tech 2-Amino-6-methoxybenzothiazole ,99% 2-Amino-6-methoxyben 6-methoxy-1,3-benzothiazol-2-amine(SALTDATA: FREE) 6-Methoxybenzothiazole-2-ylamine 2-AMino-6-Methoxybenzothiazole, 98% 5GR Benzothiazole, 2-amino-6-methoxy- 2-Amino-6-methoxybenzothiazole> 2-Amino-6-methoxybenzothiazoleidoxaline 2-Amino-6-methoxybenzothiazole ISO 9001：2015 REACH 2-Amino-6-methoxybenzothiazole?New 2-Amino-6-methoxybenzothiazole > 98% puriss for synthesis 2-AMINO-6- METHOXYLBENZOTHIAZOLE 2-amino-6-methoxy-benzthiazole 2-Amino-6-methoxybenzothiazole, 97% 2-Amino-6-methoxy-benzo[d]thiazole 6-METHOXYBENZO[D]THIAZOL-2-AMINE 2-Amino-6-methoxy-1,3-benzothiazol 1747-60-0 1747-65-2 747-60-0 1747-91-6 C8H8N2OS Building Blocks Thiazoles Heterocyclic Building Blocks Building Blocks Heterocyclic Building Blocks Thiazoles Heterocyclic Compounds Sulphur Derivatives Intermediates of Dyes and Pigments BENZOTHIAZOLE