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FENOBAM

FENOBAM Structure
FENOBAM structure
CAS No.
57653-26-6
Chemical Name:
FENOBAM
Synonyms
FENOBAM;Mcn-3377;Fenobam, 10 mM in DMSO;Fenobam, mGlu5 antagonist;1-(3-chlorophenyl)-3-(3-methyl-5-oxo-4H-imidazol-2-yl)urea;1-(3-Chlorophenyl)-3-(1-methyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl)urea;1-(3-Chlorophenyl)-3-(4,5-dihydro-1-methyl-4-oxo-1H-imidazol-2-yl)urea;N-(3-CHLOROPHENYL)-N'-(4,5-DIHYDRO-1-METHYL-4-OXO-1H-IMIDAZOL-2-YL)UREA;N-(3-CHLOROPHENYL)-N'-(4,5-DIHYDRO-1-METHYL-4-OXO-1H-IMIDAZOLE-2-YL)UREA;Urea, N-(3-chlorophenyl)-N'-(4,5-dihydro-1-methyl-4-oxo-1H-imidazol-2-yl)-
CBNumber:
CB0155115
Molecular Formula:
C11H11ClN4O2
Molecular Weight:
266.68
MDL Number:
MFCD00868019
MOL File:
57653-26-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-14 16:49:18
Request For Quotation

FENOBAM Properties

Density 1.47±0.1 g/cm3(Predicted)
storage temp. Store at RT
solubility DMSO: >20mg/mL
pka 8.32±0.20(Predicted)
form solid
color white
InChI 1S/C11H11ClN4O2/c1-16-6-9(17)14-10(16)15-11(18)13-8-4-2-3-7(12)5-8/h2-5H,6H2,1H3,(H2,13,14,15,17,18)
InChIKey DWPQODZAOSWNHB-UHFFFAOYSA-N
SMILES CN1CC(=O)N=C1NC(=O)Nc2cccc(Cl)c2
FDA UNII 078RCY7I27
UNSPSC Code 12352202
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)
GHS06
Signal word  Danger
Hazard statements  H300-H315-H319-H335
Precautionary statements  P233-P260-P261-P264-P270-P271-P280-P301+P310-P302+P352-P304-P304+P340-P305+P351+P338-P312-P321-P330-P332+P313-P337+P313-P340-P362-P403-P403+P233-P405-P501
PPE Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Hazard Codes  T
Risk Statements  25
Safety Statements  45
RIDADR  UN 2811 6.1 / PGIII
WGK Germany  3
Storage Class 11 - Combustible Solids

FENOBAM price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich F0430 Fenobam ≥98% (HPLC), solid 57653-26-6 5mg $136 2026-04-30 Buy
Sigma-Aldrich F0430 Fenobam ≥98% (HPLC), solid 57653-26-6 25mg $508 2026-04-30 Buy
Sigma-Aldrich 5.04684 Fenobam - CAS 57653-26-6 - Calbiochem 57653-26-6 5MG $144 2023-01-07 Buy
Usbiological 449991 Fenobam 57653-26-6 5mg $340 2026-06-03 Buy
Usbiological 449991 Fenobam 57653-26-6 10mg $468 2026-06-03 Buy
Product number Packaging Price Buy
F0430 5mg $136 Buy
F0430 25mg $508 Buy
5.04684 5MG $144 Buy
449991 5mg $340 Buy
449991 10mg $468 Buy

FENOBAM Chemical Properties, Uses, Production

Uses

Sedative-hypnotic.

Uses

Fenobam is a potent and selective non-competitive mGluR5 antagonist.

Biological Activity

Primary Target
mGlu6 receptors', 'Target Ki: 54 nM and 31 nM at recombinant mGlu6 receptors of r at and human, respectively

in vivo

Fenobam (30-60 mg/kg; p.o.; 3 times a week) significantly inhibits self-administration behavior in rats[3].

Animal Model:Male Long-Evans rats (250-300 g)[3].
Dosage:30-60 mg/kg
Administration:Oral administration; 3 times a week.
Result:Inhibited self-administration.

IC 50

mGluR5: 84 nM (IC50); rat mGluR5: 54 nM (Kd); human mGluR5: 31 nM (Kd)

storage

Room temperature

FENOBAM Preparation Products And Raw materials

Raw materials

Preparation Products

FENOBAM Suppliers

Global Suppliers ( 92)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Ascent Scientific 4401179829988 customerservice@ascentscientific.co.uk United Kingdom 279 60
LGM Pharma 1-(800)-881-8210 inquiries@lgmpharma.com United States 2110 70
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8435 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Supplier Advantage
J & K SCIENTIFIC LTD. 76
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Ascent Scientific 60
LGM Pharma 70
Bide Pharmatech Ltd. 60
EMMX Biotechnology LLC 60
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60
BOC Sciences 58
TargetMol Chemicals Inc. 58

View Latest Price from FENOBAM manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Fenobam pictures 2026-07-14 Fenobam
57653-26-6
 $30.00-103.00 99.93% 10g TargetMol Chemicals Inc.
  • Fenobam pictures
  • Fenobam
    57653-26-6
  • $30.00-103.00
  • 99.93%
  • TargetMol Chemicals Inc.

FENOBAM Spectrum

FENOBAM(57653-26-6)1HNMR

57653-26-6 (FENOBAM) Related Search:

3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]pyridine Carbamoyl-guanidine amidino urea salt Creatinine hydrochloride Creatinine 2-amino-1,5-dihydro-4H-imidazol-4-one
FENOBAM

1of2

FENOBAM 1-(3-Chlorophenyl)-3-(4,5-dihydro-1-methyl-4-oxo-1H-imidazol-2-yl)urea Mcn-3377 N-(3-CHLOROPHENYL)-N'-(4,5-DIHYDRO-1-METHYL-4-OXO-1H-IMIDAZOL-2-YL)UREA N-(3-CHLOROPHENYL)-N'-(4,5-DIHYDRO-1-METHYL-4-OXO-1H-IMIDAZOLE-2-YL)UREA Urea, N-(3-chlorophenyl)-N'-(4,5-dihydro-1-methyl-4-oxo-1H-imidazol-2-yl)- Fenobam,anxiolytic,brain-penetrant,mGluR,nonbenzodiazepine,Inhibitor,addiction,inhibit,cocaine,Metabotropic glutamate receptors 1-(3-Chlorophenyl)-3-(1-methyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl)urea Fenobam, mGlu5 antagonist Fenobam, 10 mM in DMSO 1-(3-chlorophenyl)-3-(3-methyl-5-oxo-4H-imidazol-2-yl)urea 57653-26-6 C11H11ClN4O2 C11H11N4O2Cl Glutamate receptor Glutamate