Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>2,5-Dimethyl pyrazine

2,5-Dimethyl pyrazine

2,5-Dimethyl pyrazine Structure
2,5-Dimethyl pyrazine structure
CAS No.
123-32-0
Chemical Name:
2,5-Dimethyl pyrazine
Synonyms
2,5-DIMETHYLPYRAZINE;2,5-Dimethylprazin;Pyrazine,2,5-dimethyl-;2,5-Dimethyl;Structural formula;2,5-Dimethylpiazine;2,5-dimethyl-pyrazin;tomfor;KETINE;GLYCOLINE
CBNumber:
CB0159355
Molecular Formula:
C6H8N2
Molecular Weight:
108.14
MDL Number:
MFCD00006147
MOL File:
123-32-0.mol
MSDS File:
SDS
Last updated:2025-10-16 15:39:32
Product description Number Pack Size Price
2,5-Dimethylpyrazine ≥98%, FG W327204 1 unit $54.6
2,5-Dimethylpyrazine ≥98%, FG W327204 1 unit $54.6
2,5-Dimethylpyrazine ≥98%, FG W327204 100g $91.8
2,5-Dimethylpyrazine ≥98%, FG W327204 500g $256
2,5-Dimethylpyrazine ≥98%, FG W327204 1kg $372
More product size
Request For Quotation

2,5-Dimethyl pyrazine Properties

Melting point 15°C
Boiling point 155 °C (lit.)
Density 0.99 g/mL at 25 °C (lit.)
refractive index n20/D 1.502(lit.)
FEMA 3272 | 2,5-DIMETHYLPYRAZINE
Flash point 147 °F
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form Liquid
pka 2.21±0.10(Predicted)
Specific Gravity 0.990
color Clear colorless to pale yellow
PH 7 (H2O)
Odor at 0.10 % in dipropylene glycol. nutty roasted baked potato
Odor Type chocolate
biological source synthetic
Sensitive Hygroscopic
JECFA Number 766
BRN 107052
Dielectric constant 2.4399999999999999
LogP 0.64
CAS DataBase Reference 123-32-0(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS) 2,5-DIMETHYLPYRAZINE
EWG's Food Scores 1
FDA UNII V99Y0MUY1Q
NIST Chemistry Reference Pyrazine, 2,5-dimethyl-(123-32-0)
EPA Substance Registry System Pyrazine, 2,5-dimethyl- (123-32-0)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38-R22
Safety Statements  26-36
RIDADR  NA 1993 / PGIII
WGK Germany  3
RTECS  UQ2800000
Hazard Note  Irritant
TSCA  Yes
HS Code  29339990
NFPA 704
2
0

2,5-Dimethyl pyrazine price More Price(59)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich W327204 2,5-Dimethylpyrazine ≥98%, FG 123-32-0 1 unit $54.6 2025-07-31 Buy
Sigma-Aldrich W327204 2,5-Dimethylpyrazine ≥98%, FG 123-32-0 1 unit $54.6 2025-07-31 Buy
Sigma-Aldrich W327204 2,5-Dimethylpyrazine ≥98%, FG 123-32-0 100g $91.8 2025-07-31 Buy
Sigma-Aldrich W327204 2,5-Dimethylpyrazine ≥98%, FG 123-32-0 500g $256 2025-07-31 Buy
Sigma-Aldrich W327204 2,5-Dimethylpyrazine ≥98%, FG 123-32-0 1kg $372 2025-07-31 Buy
Product number Packaging Price Buy
W327204 1 unit $54.6 Buy
W327204 1 unit $54.6 Buy
W327204 100g $91.8 Buy
W327204 500g $256 Buy
W327204 1kg $372 Buy

2,5-Dimethyl pyrazine Chemical Properties,Uses,Production

Chemical Properties

clear colorless to pale yellow liquid

Chemical Properties

2,5-Dimethylpyrazine has a characteristic odor of earthy, potato-like odor.

Occurrence

Reported to be present in bakery products, roasted barley, cocoa products, roasted coffee, dairy products, pork, peanuts, pecans, filberts, popcorn, potato products, rum and whiskey, soy products; a volatile component in roasted filberts and in potato chips; reportedly identified in the fat of cooked beef; also reported found in toasted off-flavors. Also reported in cheeses, butter, boiled eggs, grilled beef, tea, barley, oats, oatmeal, soybeans, heated beans, kohlrabi, shrimp and mushrooms. Also reported found in coffee, potato chips and shrimp

Uses

2,5-Dimethyl pyrazine is used for blending food, nuts and beverage flavors.

Uses

2,5-Dimethylpyrazine is used as a reagent in the synthesis of bone-targeted proteasome inhibitors for multiple myeloma (MM). 2,5-Dimethylpyrazine is also used in the preparation of 3-Methyl-2,5-bis-(2-hydroxyethyl)pyrazine (M295340); a degredation product of Clavulanic Acid (C563750) which is a β-lactamase inhibitor, typically added to amoxicillin to increase its effectiveness.

Definition

ChEBI: 2,5-Dimethylpyrazine is a member of pyrazines.

Application

2,5-Dimethyl pyrazine is held chiefly responsible for the typical flavor of Potato Chips (oil-fried, thin-sliced Potato). It has therefore been manufactured synthetically and is used in the reconditioning of commercial products, such as Potato Chips and the packaging material for same, and also for reconditioning of "instant" coffee.

Preparation

By the interaction of acrolein and ammonia when heated in glycerol in the presence of ammonium salts; by self-condensation of aminoacetone, followed by oxidation with mercury chloride.

Aroma threshold values

Detection: 80 ppb to 1.8 ppm

Taste threshold values

Taste characteristics at 7.5 ppm: musty, potato, cocoa and nutty with a fatty and oily nuance

General Description

2,5-Dimethylpyrazine is a pyrazine compound that is mainly formed in food products such as cooked rice or roasted peanuts due to the Maillard reaction between sugars and proteins during cooking or roasting process.

Safety Profile

Moderately toxic by ingestion and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx

Purification Methods

Purify it via its picrate (m 150o) which is decomposed with a base (e,g, KOH) and distilled. [Wiggins and Wise J Chem Soc 4780 1956]. [Beilstein 23/5 V 403.]

2,5-Dimethyl pyrazine synthesis

1674-56-2
123-32-0
Synthesis of 2,5-Dimethyl pyrazine from (±)-1-Amino-2-propanol

2,5-Dimethyl pyrazine Preparation Products And Raw materials

Raw materials

Acrolein Pyrazine, 2,5-dimethyl-3-propyl- (8CI,9CI) 2-Methyl-5-sec-butylpyrazine azidoacetone 2,4-OCTADIENE
2-methyl-5-propyl-pyrazine 1,3-OCTADIENE 2-AMINO-2-PROPANOL (E)-2-oxopropanal oxime 2-ISOBUTYL-3-METHYLPYRAZINE
AMINOACETONE HYDROCHLORIDE DL-Alaninol 2,6-Dimethylpiperazine

1of3

Preparation Products

trans-2,5-Dimethylpiperazine 2,6-Dimethylpyrazine Pyrimidine, 2,4-dimethyl- (6CI,7CI,8CI,9CI) Pyrazine-2,5-dicarboxylic acid pyrazine-2,5-dicarbaldehyde

2,5-Dimethyl pyrazine Suppliers

Global( 593)Suppliers
Supplier Tel Email Country ProdList Advantage
Changzhou AniKare Pharmatech Co., Ltd.
+86-0519-8359-8696 +8618018249389 sales@anikare.com China 9942 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8615350571055 Sibel@chuanghaibio.com China 8772 58
Sichuan Zhuoyu Yantang Technology Co., Ltd. 		+8613288715578 sales@sichuanzyyt.com China 12247 58
Hebei Yanxi Chemical Co., Ltd. 		+8618531123677 faithe@yan-xi.com China 5853 58
Shanghai UCHEM Inc. 		+862156762820 +86-13564624040 sales@myuchem.com China 8422 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-13131129325 sales1@chuanghaibio.com China 5251 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20175 58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		+8613343047651 admin@zlchemi.com China 3692 58
Shandong Deshang Chemical Co., Ltd. 		+86-0531-8875-2665 +8613153039501 info@deshangchem.com China 661 58
JINING XINHE CHEMICAL CO., LTD 		+8615318402391 sales@xinhepharma.com China 809 58
Supplier Advantage
Changzhou AniKare Pharmatech Co., Ltd.
58
Hebei Chuanghai Biotechnology Co., Ltd 		58
Sichuan Zhuoyu Yantang Technology Co., Ltd. 		58
Hebei Yanxi Chemical Co., Ltd. 		58
Shanghai UCHEM Inc. 		58
Hebei Chuanghai Biotechnology Co,.LTD 		58
Henan Fengda Chemical Co., Ltd 		58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		58
Shandong Deshang Chemical Co., Ltd. 		58
JINING XINHE CHEMICAL CO., LTD 		58

Related articles

View Lastest Price from 2,5-Dimethyl pyrazine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,5-Dimethylpyrazine pictures 2025-10-17 2,5-Dimethylpyrazine
123-32-0
 US $36.00-295.00 / g 5g 0.98 25kg Shanghai UCHEM Inc.
2,5-Dimethyl pyrazine pictures 2025-10-17 2,5-Dimethyl pyrazine
123-32-0
 US $10.00 / KG 1KG 99% 100 mt Hebei Chuanghai Biotechnology Co., Ltd
2,5-Dimethylpyrazine pictures 2025-10-16 2,5-Dimethylpyrazine
123-32-0
 US $91.00-39.00 / mg 99.92% 10g TargetMol Chemicals Inc.

2,5-Dimethyl pyrazine Spectrum

2,5-Dimethyl pyrazine(123-32-0)MS2,5-Dimethyl pyrazine(123-32-0)1HNMR2,5-Dimethyl pyrazine(123-32-0)13CNMR2,5-Dimethyl pyrazine(123-32-0)IR12,5-Dimethyl pyrazine(123-32-0)Raman2,5-Dimethyl pyrazine(123-32-0)ESR

123-32-0(2,5-Dimethyl pyrazine)Related Search:

2-Methylpyrazine 2,5-Dibromopyrazine Dimethyl carbonate Dimethyl ether Dimethyl fumarate
Sulfachoropyrazine sodium Dacthal Pyrazinamide N,N-Dimethylformamide Dimethyl phthalate
Dimethyl sulfate ETHANE Glipizide Dimethyl sulfoxide Dimethyl disulfide
Pyrazine 2,6-Dimethylpyrazine 3-Ethyl-2,5-diMethylpyrazine

1of4

2,5-Dimethylprazin 2,5-Dimethylpyrazine (contains 2,6-isomer) 2,5-DIMETHYL PYRAZINE, NATURAL 2,5-Dimethylpyrazine,99% 5-diMethyl pyrazine 2,5-DiMethylpyrazine, 99% 25GR 2,5-DiMethylpyrazine, 99% 5GR 2,5-Dimethylpyrazine, Research grade 2,5-Dimethyl pyrazine >=99.0% 2,5-DIMETHYLPYRAZINE FOR SYNTHESIS 2,5-DiMethyl pyrazzine Natural 2,5-DiMethyl pyrazine 2,5- twoMethyl pyrazine tomfor 2,5-dimethyl-pyrazin 2,5 AND 2,6-DIMETHYL PYRAZINE 2,5-DIMETHYL-1,4-DIAZINE 2,5-DIMETHYLPYRAZINE 2,5-DIMETHYLPYRAZINE AND 2,6-DIMETHYLPYRAZINE 2,5(2,6)-DIMETHYLPYRAZINE MIXTURE 2,5-Dimethyl paradiazine 2 5-DIMETHYLPYRAZINE FCC 2,5-Dimethyl-p-diazine 2,5-Dimethylpiazine dimethylpyrazine,2,5-dimethylpyrazine,2,5-dimethyl-1,4-diazine 2,5-Dimethyl Pyrazine,2,5-dimethyl- KETINE GLYCOLINE FEMA 3272 FEMA NUMBER 3272 FEMA NUMBER 3272 AND 3273 2,5(or6)-Dimethyl pyrazine 2,5-DIMETHYLPYRAZINE (CONTAINS CA. 5% 2,6-ISOMER) 94+% 2,5-DIMETHYL PYRAZINE FEMA NO.3272 2,5-DIMETHYLPYRAZINE (CONTAINS 2,6-ISOMER) 80+% 2,3,5-TRMETHYLPYRAZINE 2,5-Dimethylpyrazine≥ 99% (GC) 2,5-Dimethylpyrazine 98+% Glipizide Impurity 17 2,5-Dimethylpyrazine > 2,5-Dimethylpyrazine, Flavour grade 2,5-Dimethylpyrazine (contains 2,6-isomer)> 2,5-Dimethyl pyrazine USP/EP/BP Structural formula 2,5-dimethyl pyrazine and 2,6-dimethyl pyrazine mixture 2, 5-Dimethyl Pyrazine CAS 123-32-0 with Best Price 2.5-Dimethyl pryazine Clomiphene Citrate 50-41-9 2,5-Dimethylpyrazine, Flavour grade in isooctane 2,5-Dimethylpyrazine, Research grade in isooctane Glipizide Impurity 42 2,5-Dimethylpyrazine, 10 mM in DMSO 123-32-0 123-23-0 3123-32-0 -NCCH3CHNCCH3CH Heterocyclic Building Blocks