2,5-Dibromopyrazine
- CAS No.
- 23229-26-7
- Chemical Name:
- 2,5-Dibromopyrazine
- Synonyms
- 2,5-Dibromopyrazine 95% (GC);5-Dibromopyrazine;2,5-DIBROMOPYRAZINE;PYRAZINE,2,5-DIBROMO;2,5-bisbromopyrazine;2,5-Dibromopyrazine>2,5-Dibromopyrazine ISO 9001：2015 REACH;3,6-Dibromopyrazine, 2,5-Dibromo-1,4-diazine
- CBNumber:
- CB0701358
- Molecular Formula:
- C4H2Br2N2
- Molecular Weight:
- 237.88
- MDL Number:
- MFCD08061601
- MOL File:
- 23229-26-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 45.0 to 49.0 °C |
|---|---|
| Boiling point | 234.0±35.0 °C(Predicted) |
| Density | 2.197 |
| Flash point | 95℃ |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | -4.28±0.10(Predicted) |
| form | powder to crystal |
| color | White to Orange to Green |
| InChI | InChI=1S/C4H2Br2N2/c5-3-1-7-4(6)2-8-3/h1-2H |
| InChIKey | KIYKHEOWZLJZSB-UHFFFAOYSA-N |
| SMILES | C1(Br)=NC=C(Br)N=C1 |
| CAS DataBase Reference | 23229-26-7 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 |
| target organs | Respiratory system |
| Hazard Codes | Xi,Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26-36/37/39 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| HS Code | 29339900 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
2,5-Dibromopyrazine price More Price(86)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 796603 | 2,5-Dibromopyrazine 95% (GC) | 23229-26-7 | 1G | $48.3 | 2026-04-30 | Buy |
| TCI Chemical | D4323 | 2,5-Dibromopyrazine >98.0%(GC) | 23229-26-7 | 1g | $22 | 2026-04-30 | Buy |
| TCI Chemical | D4323 | 2,5-Dibromopyrazine >98.0%(GC) | 23229-26-7 | 5g | $62 | 2026-04-30 | Buy |
| AstaTech | 52689 | 2,5-DIBROMOPYRAZINE 97% | 23229-26-7 | 5G | $33 | 2026-04-30 | Buy |
| AstaTech | 52689 | 2,5-DIBROMOPYRAZINE 97% | 23229-26-7 | 25G | $99 | 2026-04-30 | Buy |
2,5-Dibromopyrazine Chemical Properties,Uses,Production
Application
2,5-Dibromopyrazine is a common organic synthon that can serve as a molecular skeleton in the synthesis of bioactive molecules.
Synthesis
5-bromopyrazin-2-amine (3 g, 17.241 mmol) and bromine (8.2 g, 51.729 mmol) were added to aq. HBr solution at -15° C. Aq. solution of sodium nitrite (2.97 g, 43.0103 mmol) was then added to the mixture over a period of 1 h at -10° C. keeping the internal temperature below 5° C. during addition and stirred for 1 h at 0° C. Progress of reaction was monitored by TLC. After reaction completion reaction mass neutralised with 40percent NaOH solution and extracted with diethyl ether. The organic layer was dried over sodium sulphate and concentrated under reduced pressure (below 30° C.) to yield 2,5-Dibromopyrazine (1 g, 24.4percent) as brown oil.
References
[1] Patent: US2017/291910, 2017, A1. Location in patent: Paragraph 0592-0594
[2] Journal of the American Chemical Society, 1949, vol. 71, p. 2798
[3] Chemistry - A European Journal, 2010, vol. 16, # 19, p. 5645 - 5660
[4] Patent: WO2004/56369, 2004, A1. Location in patent: Page/Page column 24-25
2,5-Dibromopyrazine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Tongchuang Pharma(Suzhou). Co., Ltd. | 0512-63263366 18912765016 | tongtf110@sina.com | China | 984 | 62 |
| Zhengzhou HQ Material Co., Ltd. | 0371-0371-67759225 13526468238 | sales@hqmat.com | China | 342 | 55 |
| Kohn & Shawn Pharmatech Co.,Ltd | 0943-8293106 | sales@kyxpharma.com | China | 297 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
View Lastest Price from 2,5-Dibromopyrazine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 2,5-Dibromopyrazine
23229-26-7
|
$1.10 | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2022-01-27 | 2,5-Dibromopyrazine
23229-26-7
|
1KG | 97.4% | 100 tons | Honest Joy Holdings Limited | ||
 |
2020-04-29 | 2,5-Dibromopyrazine
23229-26-7
|
1KG | 99.0%+ | 800 tons | Shaanxi Dideu Medichem Co. Ltd |
-
- 2,5-Dibromopyrazine
23229-26-7
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 2,5-Dibromopyrazine
23229-26-7
- $0.00
- 97.4%
- Honest Joy Holdings Limited
-
- 2,5-Dibromopyrazine
23229-26-7
- 99.0%+
- Shaanxi Dideu Medichem Co. Ltd
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