4-Iodopyridine-2-carboxylic acid
- CAS No.
- 405939-79-9
- Chemical Name:
- 4-Iodopyridine-2-carboxylic acid
- Synonyms
- AKOS BBS-00006014;4-Iodopicolinicaci;IFLAB-BB F1926-0015;4-IODOPICOLINIC ACID;4-Iodopyridine-2-carboxylic acid;4-IODO-2-PYRIDINECARBOXYLIC ACID;2-Pyridinecarboxylic acid, 4-iodo-;4-4-Iodopyridine-2-carboxylic acid;4-Iodopyridine-2-carboxylic acid 96%;4-Iodopyridine-2-carboxylic acid ,97%
- CBNumber:
- CB0172716
- Molecular Formula:
- C6H4INO2
- Molecular Weight:
- 249.01
- MDL Number:
- MFCD03426666
- MOL File:
- 405939-79-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36-37/38/39 |
| Safety Statements | 26-36/37/39 |
| Hazard Note | Irritant |
| HS Code | 29333990 |
4-Iodopyridine-2-carboxylic acid price More Price(50)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 280958 | 4-Iodopyridine-2-carboxylic acid Asreported | 405939-79-9 | 500mg | $347 | 2026-06-03 | Buy |
| Usbiological | 280958 | 4-Iodopyridine-2-carboxylic acid Asreported | 405939-79-9 | 1g | $608 | 2026-06-03 | Buy |
| Usbiological | 280958 | 4-Iodopyridine-2-carboxylic acid Asreported | 405939-79-9 | 2g | $852 | 2026-06-03 | Buy |
| Usbiological | 280958 | 4-Iodopyridine-2-carboxylic acid Asreported | 405939-79-9 | 5g | $1677 | 2026-06-03 | Buy |
| Usbiological | 280958 | 4-Iodopyridine-2-carboxylic acid Asreported | 405939-79-9 | 10g | $2480 | 2026-06-03 | Buy |
4-Iodopyridine-2-carboxylic acid Chemical Properties, Uses, Production
Chemical Properties
White power
Synthesis
24484-93-3
405939-79-9
Methyl 4-chloropyridinecarboxylate (CYD-1-1, 4.8 g, 27.9 mmol) was mixed with 57% hydriodic acid (26.6 mL, 232.2 mmol) and 50% aqueous hypophosphorous acid (1.32 mL, 12.0 mmol), and the reaction was stirred for 2 hr at 85 °C, and then warmed up to 107 °C to continue the reaction overnight. Upon completion of the reaction, the mixture was cooled to 95 °C and 8.4 mL of 10N aqueous sodium hydroxide solution was slowly added. The mixture was continued to cool to room temperature and stirred for 1 h. A yellow solid was precipitated. After filtration, washing with cold water and vacuum drying overnight, 4-iodopyridinecarboxylic acid (6.8 g, 89% yield) was obtained. The resulting 4-iodopyridinecarboxylic acid (6.73 g, 27.0 mmol) was dissolved in methanol (101 mL), concentrated sulfuric acid (508 μL) was added, and the reaction was refluxed at 80 °C for 2 days. After completion of the reaction, the solvent was evaporated and the residue was dissolved in saturated sodium bicarbonate solution and extracted with ethyl acetate (3 times). The organic layers were combined, washed with saturated brine, dried over anhydrous Na2SO4 and the solvent evaporated. The residue was purified by silica gel column chromatography with 1:3 ethyl acetate-hexane as eluent to afford methyl 4-iodopyridinecarboxylate (CYD-1-4, 2.88 g, 40% overall yield in two steps) as a yellow solid with a melting point of 73-74 °C.1H NMR (600 MHz, CDCl3) δ 8.50 (d, 1H, J=1.2 Hz), 8.39 (d, 1H, J = 5.4 Hz), 7.87 (dd, 1H, J = 1.8 Hz and 4.8 Hz), 4.02 (s, 3H).
References
[1] Patent: WO2013/86266, 2013, A2. Location in patent: Paragraph 00092
[2] Patent: US9533973, 2017, B2. Location in patent: Page/Page column 34-35
[3] Patent: WO2004/16632, 2004, A2. Location in patent: Page 57-58
4-Iodopyridine-2-carboxylic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Nanjing Vital Chemical Co., Ltd. | Please Send Email 18652950785 | chemweiao@163.com | China | 4368 | 65 |
| Dtchem Laboratories,（Gan Su）Co.,Ltd. | 18993961550 18993966060 | sales@techbiochem.com | China | 774 | 61 |
| Shanghai Jian Chao Chemical Technology Co., Ltd. | 150-2103-5486 18017383231 | 983544897@qq.com | China | 9335 | 55 |
View Latest Price from 4-Iodopyridine-2-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | 4-iodopyridine-2-carboxylic acid
405939-79-9
|
$1.10-9.90 | 1kg | 99%min | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2026-08-20 | 4-IODOPYRIDINE-2-CARBOXYLIC ACID
405939-79-9
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2019-07-06 | 4-IODOPYRIDINE-2-CARBOXYLIC ACID
405939-79-9
|
$1.00 | 1kg | 98% | 200KG | Career Henan Chemical Co |
-
- 4-iodopyridine-2-carboxylic acid
405939-79-9
- $1.10-9.90
- 99%min
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 4-IODOPYRIDINE-2-CARBOXYLIC ACID
405939-79-9
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 4-IODOPYRIDINE-2-CARBOXYLIC ACID
405939-79-9
- $1.00
- 98%
- Career Henan Chemical Co
405939-79-9 (4-Iodopyridine-2-carboxylic acid) Related Search:
1of3
