2,4-Dichlorophenylacetonitrile
- CAS No.
- 6306-60-1
- Chemical Name:
- 2,4-Dichlorophenylacetonitrile
- Synonyms
- 2,4-DICHLOROBENZYL CYANIDE;2-(2,4-Dichlorophenyl)acetonitrile;2,4-DCCN;AI312073;AI3 12073;AI3-12073;2,4-Dichlorophenylac;2,4-dichloro cyanobenzene;4-Dichlorophenylacetonitrile;2,4-DichlorobenzylCyanide>
- CBNumber:
- CB0191124
- Molecular Formula:
- C8H5Cl2N
- Molecular Weight:
- 186.04
- MDL Number:
- MFCD00001899
- MOL File:
- 6306-60-1.mol
- MSDS File:
- SDS
| Melting point | 58-61 °C (lit.) |
|---|---|
| Boiling point | 306.06°C (rough estimate) |
| Density | 1.4274 (rough estimate) |
| refractive index | 1.5690 (estimate) |
| Flash point | 176 °C |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to crystal |
| color | White to Light yellow to Light orange |
| BRN | 2047688 |
| Exposure limits | NIOSH: IDLH 25 mg/m3 |
| InChI | 1S/C8H5Cl2N/c9-7-2-1-6(3-4-11)8(10)5-7/h1-2,5H,3H2 |
| InChIKey | VJARIBGMDPJLCL-UHFFFAOYSA-N |
| SMILES | Clc1ccc(CC#N)c(Cl)c1 |
| CAS DataBase Reference | 6306-60-1(CAS DataBase Reference) |
| FDA UNII | D9J4C5M11E |
| NIST Chemistry Reference | Benzeneacetonitrile, 2,4-dichloro-(6306-60-1) |
| EPA Substance Registry System | (2,4-Dichlorophenyl)acetonitrile (6306-60-1) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| RIDADR | 3276 | |||||||||
| WGK Germany | 1 | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29269090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
2,4-Dichlorophenylacetonitrile price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 178462 | 2,4-Dichlorophenylacetonitrile 98% | 6306-60-1 | 25g | $48.2 | 2023-06-20 | Buy |
| TCI Chemical | D1792 | 2,4-Dichlorobenzyl Cyanide >98.0%(GC) | 6306-60-1 | 25g | $36 | 2026-04-30 | Buy |
| Apolloscientific | OR10901 | 2,4-Dichlorophenylacetonitrile >98% | 6306-60-1 | 25g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR10901 | 2,4-Dichlorophenylacetonitrile >98% | 6306-60-1 | 100g | $44 | 2026-06-04 | Buy |
| Apolloscientific | OR10901 | 2,4-Dichlorophenylacetonitrile >98% | 6306-60-1 | 500g | $139 | 2026-06-04 | Buy |
2,4-Dichlorophenylacetonitrile Chemical Properties, Uses, Production
Chemical Properties
white to light yellow crystal powder
Uses
2,4-Dichlorophenylacetonitrile was used in the synthesis of 2,4-dichloromandelic acid.
Synthesis
773837-37-9
94-99-5
6306-60-1
General method: 2,4-dichlorobenzyl chloride (1.0 mmol) was mixed with sodium cyanide (2 mmol) in deionized water (5 mL) and polyethylene glycol modified diisocyanate (PEG-MDIL, 0.2 g) was added. The reaction suspension was placed under reflux conditions and the reaction mixture was stirred using a magnetic stirrer for the reaction time referred to in Table 2.After completion of the reaction, the mixture was extracted with ether (2 × 10 mL). The organic extracts were combined, dried with anhydrous calcium chloride and subsequently concentrated under reduced pressure. By this method, the target product 2,4-dichlorophenylacetonitrile was obtained in good to excellent isolated yields (see Scheme 3).
References
[1] Organic Preparations and Procedures International, 2011, vol. 43, # 3, p. 285 - 291
[2] Journal of Molecular Liquids, 2015, vol. 202, p. 34 - 39
[3] Journal of Molecular Catalysis A: Chemical, 2012, vol. 365, p. 80 - 86
[4] Applied Organometallic Chemistry, 2018, vol. 32, # 2,
[5] Catalysis Communications, 2012, vol. 18, p. 102 - 105
2,4-Dichlorophenylacetonitrile Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shandong Baizhe New Materials Co., Ltd | 13375512898 | 13375512898@163.com | China | 300 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| future industrial shanghai co., ltd | 400-0066400 13621662912 | sales@jonln.com | China | 1989 | 65 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TAIYUAN RHF CO.,LTD. | +86 351 7031519 | sales@RHFChem.com | China | 2334 | 56 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 |
View Latest Price from 2,4-Dichlorophenylacetonitrile manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-09-02 | 2,4-Dichlorophenylacetonitrile
6306-60-1
|
$5.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
![]() |
2021-08-12 | 2,4-Dichlorophenylacetonitrile
6306-60-1
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
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2021-07-02 | 2,4-Dichlorobenzyl Cyanide
6306-60-1
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-

- 2,4-Dichlorophenylacetonitrile
6306-60-1
- $5.00
- 99%
- Henan Fengda Chemical Co., Ltd
-

- 2,4-Dichlorophenylacetonitrile
6306-60-1
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-

- 2,4-Dichlorobenzyl Cyanide
6306-60-1
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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