ChemicalBook >> CAS DataBase List >>2,4-Dichlorophenylacetonitrile

2,4-Dichlorophenylacetonitrile

CAS No.
6306-60-1
Chemical Name:
2,4-Dichlorophenylacetonitrile
Synonyms
2,4-DICHLOROBENZYL CYANIDE;2-(2,4-Dichlorophenyl)acetonitrile;2,4-DCCN;AI312073;AI3 12073;AI3-12073;2,4-Dichlorophenylac;2,4-dichloro cyanobenzene;4-Dichlorophenylacetonitrile;2,4-DichlorobenzylCyanide>
CBNumber:
CB0191124
Molecular Formula:
C8H5Cl2N
Molecular Weight:
186.04
MDL Number:
MFCD00001899
MOL File:
6306-60-1.mol
MSDS File:
SDS
Last updated:2026-05-27 17:21:38

2,4-Dichlorophenylacetonitrile Properties

Melting point 58-61 °C (lit.)
Boiling point 306.06°C (rough estimate)
Density 1.4274 (rough estimate)
refractive index 1.5690 (estimate)
Flash point 176 °C
storage temp. Sealed in dry,Room Temperature
solubility soluble in Methanol
form powder to crystal
color White to Light yellow to Light orange
BRN 2047688
Exposure limits NIOSH: IDLH 25 mg/m3
InChI 1S/C8H5Cl2N/c9-7-2-1-6(3-4-11)8(10)5-7/h1-2,5H,3H2
InChIKey VJARIBGMDPJLCL-UHFFFAOYSA-N
SMILES Clc1ccc(CC#N)c(Cl)c1
CAS DataBase Reference 6306-60-1(CAS DataBase Reference)
FDA UNII D9J4C5M11E
NIST Chemistry Reference Benzeneacetonitrile, 2,4-dichloro-(6306-60-1)
EPA Substance Registry System (2,4-Dichlorophenyl)acetonitrile (6306-60-1)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-20/21/22
Safety Statements  26-36/37/39
RIDADR  3276
WGK Germany  1
HazardClass  6.1
PackingGroup  III
HS Code  29269090
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 0

2,4-Dichlorophenylacetonitrile price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 178462 2,4-Dichlorophenylacetonitrile 98% 6306-60-1 25g $48.2 2023-06-20 Buy
TCI Chemical D1792 2,4-Dichlorobenzyl Cyanide >98.0%(GC) 6306-60-1 25g $36 2026-04-30 Buy
Apolloscientific OR10901 2,4-Dichlorophenylacetonitrile >98% 6306-60-1 25g $21 2026-06-04 Buy
Apolloscientific OR10901 2,4-Dichlorophenylacetonitrile >98% 6306-60-1 100g $44 2026-06-04 Buy
Apolloscientific OR10901 2,4-Dichlorophenylacetonitrile >98% 6306-60-1 500g $139 2026-06-04 Buy
Product number Packaging Price Buy
178462 25g $48.2 Buy
D1792 25g $36 Buy
OR10901 25g $21 Buy
OR10901 100g $44 Buy
OR10901 500g $139 Buy

2,4-Dichlorophenylacetonitrile Chemical Properties, Uses, Production

Chemical Properties

white to light yellow crystal powder

Uses

2,4-Dichlorophenylacetonitrile was used in the synthesis of 2,4-dichloromandelic acid.

Synthesis

sodium:cyanide

773837-37-9

2,4-Dichlorobenzyl chloride

94-99-5

2,4-Dichlorophenylacetonitrile

6306-60-1

General method: 2,4-dichlorobenzyl chloride (1.0 mmol) was mixed with sodium cyanide (2 mmol) in deionized water (5 mL) and polyethylene glycol modified diisocyanate (PEG-MDIL, 0.2 g) was added. The reaction suspension was placed under reflux conditions and the reaction mixture was stirred using a magnetic stirrer for the reaction time referred to in Table 2.After completion of the reaction, the mixture was extracted with ether (2 × 10 mL). The organic extracts were combined, dried with anhydrous calcium chloride and subsequently concentrated under reduced pressure. By this method, the target product 2,4-dichlorophenylacetonitrile was obtained in good to excellent isolated yields (see Scheme 3).

References

[1] Organic Preparations and Procedures International, 2011, vol. 43, # 3, p. 285 - 291
[2] Journal of Molecular Liquids, 2015, vol. 202, p. 34 - 39
[3] Journal of Molecular Catalysis A: Chemical, 2012, vol. 365, p. 80 - 86
[4] Applied Organometallic Chemistry, 2018, vol. 32, # 2,
[5] Catalysis Communications, 2012, vol. 18, p. 102 - 105

773837-37-9
20443-99-6
6306-60-1
Synthesis of 2,4-Dichlorophenylacetonitrile from sodium:cyanide and 2,4-Dichlorobenzyl bromide
Global Suppliers ( 302)
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Shandong Baizhe New Materials Co., Ltd 13375512898 13375512898@163.com China 300 58
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Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
future industrial shanghai co., ltd 400-0066400 13621662912 sales@jonln.com China 1989 65
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66

View Latest Price from 2,4-Dichlorophenylacetonitrile manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
	2,4-Dichlorophenylacetonitrile pictures 2026-09-02 2,4-Dichlorophenylacetonitrile
6306-60-1
$5.00 1KG 99% Henan Fengda Chemical Co., Ltd
2,4-Dichlorophenylacetonitrile pictures 2021-08-12 2,4-Dichlorophenylacetonitrile
6306-60-1
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
2,4-Dichlorobenzyl Cyanide pictures 2021-07-02 2,4-Dichlorobenzyl Cyanide
6306-60-1
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
2,4-DICHLOROPHENYLACETONITRILE 2,4-DCCN 2,4-Dichlorobenzeneacetonitrile Acetonitrile, (2,4-dichlorophenyl)- 2,4-dichloro cyanobenzene 2,4-Dichlorophenylacetonitrile,98% (2,4-Dichlorphenyl)acetonitril 2,4-DICHLOROPHENYLACETONITRILE / 2,4-DICHLOROBENZYL CYANIDE 11) 2,4-DI CHLORO BENZYL CYANIDE Benzeneacetonitrile, 2,4-dichloro- 2,4-DICHLOROPHENYLACETONITRILE, 99+% 2,4-Dichlorophenylac 4-Dichlorophenylacetonitrile 2,4- twochlorophenylacetonitrile 2,4-Dichlorophenylacetonitrile 98% 2,4-DichlorobenzylCyanide> AI3 12073 AI312073 AI3-12073 2-(2,4-Dichlorophenyl)acetonitrile 2,4-DICHLOROBENZYL CYANIDE 6306-60-1 6303-60-1 Cl2C6H3CH2CN ARYL ISOCYANATE C8 to C9 Building Blocks Organic Building Blocks Nitrogen Compounds Cyanides/Nitriles Building Blocks C8 to C9 Chemical Synthesis Cyanides/Nitriles Nitrogen Compounds Organic Building Blocks Aromatic Phenylacetic Acids and Derivatives Nitrile