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FR 139317

FR 139317 structure

CAS No.: 142375-60-8

Chemical Name:: FR 139317

Synonyms: FR 139317;FR139317,CID107810;FR 139317, ETA receptor antagonist;N,N-hexamethylenecarbamoyl-leu-N-*methyl-D-trp-D-;(N,N-HEXAMETHYLENE) CARBAMOYL-LEU-D-TRP(N-ME)-D-2-PYA;(HEXAHYDRO-1H-AZEPINYL)CARBONYL-LEU-D-(1-ME)-TRP-DPAL;(HEXAHYDRO-1H-AZEPINYL)CARBONYL-LEU-DTRP(ME)-D-ALA(2-PYRIDYL)-OH;D-Alanine, N-((hexahydro-1H-azepin-1-yl)carbonyl)-L-leucyl-1-methyl-D-tryptophyl-3-(2-pyridinyl)-;N-[N-[N-[(HEXAHYDRO-1H-AZEPIN-1-YL)CARBONYL]-L-LEUCYL]-1-METHYL-D-TRYPTOPHYL]-3-(2-PYRIDINYL)-D-ALANINE;D-Alanine, N-(N-(N-((hexahydro-1H-azepin-1-yl)carbonyl)-L-leucyl)-1-methyl-D-tryptophyl)-3-(2-pyridinyl)-

CBNumber:: CB0216568

Molecular Formula:: C33H44N6O5

Molecular Weight:: 604.74

MDL Number:: MFCD00467722

MOL File:: 142375-60-8.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-27 17:00:41

Request For Quotation

FR 139317 Properties

Boiling point	943.9±65.0 °C(Predicted)
Density	1.27±0.1 g/cm3(Predicted)
storage temp.	Desiccate at +4°C
solubility	Soluble to 100 mM in 1eq. HCl and to 100 mM in DMSO
form	Powder
pka	2.68±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P280-P305+P351+P338

FR 139317 price More Price(14)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	255334	FR 139317 Asreported	142375-60-8	10mg	$502	2026-06-03	Buy
Usbiological	255334	FR 139317 Asreported	142375-60-8	50mg	$1437	2026-06-03	Buy
Biosynth	SFA37560	FR 139317	142375-60-8	25mg	$905.25	2026-06-05	Buy
Biosynth	SFA37560	FR 139317	142375-60-8	50mg	$1448	2026-06-05	Buy
Biosynth	SFA37560	FR 139317	142375-60-8	100mg	$2014	2026-06-05	Buy

Product number	Packaging	Price	Buy
255334	10mg	$502	Buy
255334	50mg	$1437	Buy
SFA37560	25mg	$905.25	Buy
SFA37560	50mg	$1448	Buy
SFA37560	100mg	$2014	Buy

FR 139317 Chemical Properties,Uses,Production

Uses

FR 139317 is a novel, potent endothelin ETA receptor antagonist.

Biological Activity

A highly potent and selective ET A endothelin receptor antagonist (K i values are 1 nM and 7.3 μ M at ET A and ET B subtypes respectively). Active in vivo .

IC 50

ET_A

FR 139317 Preparation Products And Raw materials

Raw materials

Preparation Products

FR 139317 Suppliers

Global( 46)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32273	50
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8435	60
Shanghai YuanYe Biotechnology Co., Ltd.	15026964105	2881489226@qq.com	China	89667	60
Nanjing Peptide Biotech Ltd.	025-58361106-805 15951641583	zhao.xu@njpeptide.com	China	9976	55
Hangzhou Peptidego Biotech Co.,Ltd.	0571-87213919 15967184799	Eric@peptidego.com	China	7872	58
Jinan Yaoyan Pharmaceutical Co., Ltd.		jnyaoyan@163.com	China	3057	58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.	meitaochem@126.com	meitaochem@126.com	China	19087	58
BOC Sciences	16314854226; +8616314854226	inquiry@bocsci.com	United States	19852	58

Supplier	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	69
GL Biochem (Shanghai) Ltd	64
Chemsky（shanghai）International Co.,Ltd.	50
EMMX Biotechnology LLC	60
Shanghai YuanYe Biotechnology Co., Ltd.	60
Nanjing Peptide Biotech Ltd.	55
Hangzhou Peptidego Biotech Co.,Ltd.	58
Jinan Yaoyan Pharmaceutical Co., Ltd.	58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.	58
BOC Sciences	58

View Lastest Price from FR 139317 manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-07-27	FR 139317 142375-60-8	$1520.00-2500.00			10g	TargetMol Chemicals Inc.

FR 139317
142375-60-8
$1520.00-2500.00
TargetMol Chemicals Inc.

FR 139317 Spectrum

FR 139317(142375-60-8)MS FR 139317(142375-60-8)IR1

142375-60-8(FR 139317)Related Search:

3-(2-Pyridyl)-D-alanine BETA-(2-PYRIDYL)-DL-ALANINE 2-Pyridinepropanol 3-PYRIDIN-2-YL-PROPIONIC ACID H2SO4 FR 139317

2-(2-Methoxyphenoxy)ethylamine 1-METHYL-2-PYRIDIN-2-YL-ETHYLAMINE N-ACETYL-D-ALA-D-ALA 1H-Azepine-1-carboxamide,hexahydro-(9CI) METHYL-(1-METHYL-2-PYRIDIN-2-YL-ETHYL)-AMINE

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FR 139317 (HEXAHYDRO-1H-AZEPINYL)CARBONYL-LEU-D-(1-ME)-TRP-DPAL (HEXAHYDRO-1H-AZEPINYL)CARBONYL-LEU-DTRP(ME)-D-ALA(2-PYRIDYL)-OH 2-((1-(Hexahydro-1H-azepinyl)carbonyl)amino-4-methylpentanoyl)-3-(-(1-methyl-1H-indolyl)propionyl)amino-3-(2-pyridyl)propionic acid D-Alanine, N-((hexahydro-1H-azepin-1-yl)carbonyl)-L-leucyl-1-methyl-D-tryptophyl-3-(2-pyridinyl)- D-Alanine, N-(N-(N-((hexahydro-1H-azepin-1-yl)carbonyl)-L-leucyl)-1-methyl-D-tryptophyl)-3-(2-pyridinyl)- (2R)-2-[[(2R)-2-[[(2S)-2-(AZEPANE-1-CARBONYLAMINO)-4-METHYLPENTANOYL]AMINO]-3-(1-METHYLINDOL-3-YL)PROPANOYL]AMINO]-3-PYRIDIN-2-YLPROPANOIC ACID FR139317,CID107810 N-[N-[N-[(HEXAHYDRO-1H-AZEPIN-1-YL)CARBONYL]-L-LEUCYL]-1-METHYL-D-TRYPTOPHYL]-3-(2-PYRIDINYL)-D-ALANINE (N,N-HEXAMETHYLENE) CARBAMOYL-LEU-D-TRP(N-ME)-D-2-PYA N,N-hexamethylenecarbamoyl-leu-N-*methyl-D-trp-D- FR 139317, ETA receptor antagonist (2R)-2-[[(2R)-2-([(2S)-2-[(1-AZEPANYLCARBONYL)AMINO]-4-METHYLPENTANOYL]AMINO)-3-(1-METHYL-1H-INDOL-3-YL)PROPANOYL]AMINO]-3-(2-PYRIDINYL)PROPANOIC ACID 142375-60-8 C33H44N6O5