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N-Methyl-bis(trifluoroacetamide)

N-Methyl-bis(trifluoroacetamide) structure

CAS No.: 685-27-8

Chemical Name:: N-Methyl-bis(trifluoroacetamide)

Synonyms: MBTFA;N-Methylbis(Tr;[Trifluoroacylating Agent];Florists Sendranthema Extract;N-Methylbistrifluororacetamide;N-METHYLBIS(TRIFLUOROACETAMIDE);N-Methylbis(trifluoroacetyl)amine;N-Methylbis(trifluoroacetyl)imide;N-METHYL-N-BIS(TRIFLUOROACETAMIDE);N-Methylbis(trifluoroacetamide)98%

CBNumber:: CB0220312

Molecular Formula:: C5H3F6NO2

Molecular Weight:: 223.07

MDL Number:: MFCD00000412

MOL File:: 685-27-8.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-27 17:23:21

Product description	Number	Pack Size	Price
N-Methyl-bis(trifluoroacetamide) for GC derivatization, ≥99.0% (GC)	65943	5ml	$248
N-Methyl-bis(trifluoroacetamide) for GC derivatization, ≥99.0% (GC)	65943	25ml	$931
N-Methylbis(trifluoroacetamide) [Trifluoroacylating Agent] >97.0%(GC)	M0671	1mL	$64
N-Methylbis(trifluoroacetamide) [Trifluoroacylating Agent] >97.0%(GC)	M0671	5mL	$179
N-Methylbis(trifluoroacetamide)	FM60414	0.01kg	$181.4

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N-Methyl-bis(trifluoroacetamide) Properties

Boiling point	121-122 °C(lit.)
Density	1.547 g/mL at 25 °C
refractive index	n20/D 1.346(lit.)
Flash point	42 °C
storage temp.	2-8°C
pka	-3.38±0.70(Predicted)
form	clear liquid
color	Colorless to Light yellow
Specific Gravity	1.547
Sensitive	Moisture Sensitive
BRN	1878402
InChI	1S/C5H3F6NO2/c1-12(2(13)4(6,7)8)3(14)5(9,10)11/h1H3
InChIKey	AWGBWLXGUPTXHF-UHFFFAOYSA-N
SMILES	CN(C(=O)C(F)(F)F)C(=O)C(F)(F)F
CAS DataBase Reference	685-27-8(CAS DataBase Reference)
NIST Chemistry Reference	Acetamide, 2,2,2-trifluoro-n-methyl-n-(trifluoroacetyl)-(685-27-8)
UNSPSC Code	12000000
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS05

Signal word

Danger

Hazard statements

H226-H314

Precautionary statements

P210-P233-P240-P280-P303+P361+P353-P305+P351+P338

PPE

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Hazard Codes

Risk Statements

10-34-44

Safety Statements

26-36/37/39-45-16

RIDADR

UN 2920 8/PG 2

WGK Germany

10-21

Hazard Note

Corrosive/Moisture Sensitive

HazardClass

PackingGroup

HS Code

29241990

Storage Class

3 - Flammable liquids

Hazard Classifications

Flam. Liq. 3
Skin Corr. 1B

Limited Quantities

1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)

NFPA 704

	2
3		0

N-Methyl-bis(trifluoroacetamide) price More Price(48)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	65943	N-Methyl-bis(trifluoroacetamide) for GC derivatization, ≥99.0% (GC)	685-27-8	5ml	$248	2026-04-30	Buy
Sigma-Aldrich	65943	N-Methyl-bis(trifluoroacetamide) for GC derivatization, ≥99.0% (GC)	685-27-8	25ml	$931	2026-04-30	Buy
TCI Chemical	M0671	N-Methylbis(trifluoroacetamide) [Trifluoroacylating Agent] >97.0%(GC)	685-27-8	1mL	$64	2026-04-30	Buy
TCI Chemical	M0671	N-Methylbis(trifluoroacetamide) [Trifluoroacylating Agent] >97.0%(GC)	685-27-8	5mL	$179	2026-04-30	Buy
Biosynth	FM60414	N-Methylbis(trifluoroacetamide)	685-27-8	0.01kg	$181.4	2026-06-04	Buy

Product number	Packaging	Price	Buy
65943	5ml	$248	Buy
65943	25ml	$931	Buy
M0671	1mL	$64	Buy
M0671	5mL	$179	Buy
FM60414	0.01kg	$181.4	Buy

N-Methyl-bis(trifluoroacetamide) Chemical Properties,Uses,Production

Chemical Properties

clear colorless liquid

Uses

Reagent for introducing trifluoroacetyl group.

reaction suitability

reagent type: derivatization reagent
reaction type: Acylations
reagent type: derivatization reagent
reaction type: Silylations

N-Methyl-bis(trifluoroacetamide) Preparation Products And Raw materials

Raw materials

Preparation Products

PHENYL TRIFLUOROACETATE

N-Methyl-bis(trifluoroacetamide) Suppliers

Global( 158)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-87569262 +86-15003564040	1056@dideu.com	China	3970	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58
Finetech Industry Limited	+86-27-8746-5837 +8619945049750	info@finetechnology-ind.com	China	9539	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52704	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	mina@chuanghaibio.com	China	18126	58
GIHI CHEMICALS CO.,LIMITED	+86-571-86217390; +8618058761490	info@gihichemicals.com	China	49890	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
Hebei Fengmu Trading Co., Ltd.	+8613393234347	Lyla@fengmuchem.com	China	2943	58

Supplier	Advantage
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Shaanxi Dideu Medichem Co. Ltd	58
SIMAGCHEM CORP	58
Finetech Industry Limited	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Hebei Chuanghai Biotechnology Co., Ltd	58
GIHI CHEMICALS CO.,LIMITED	58
Aladdin Scientific	58
Hebei Fengmu Trading Co., Ltd.	58

View Lastest Price from N-Methyl-bis(trifluoroacetamide) manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-04-04	N-Methyl-bis(trifluoroacetamide) 685-27-8		1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2021-08-12	N-Methyl-bis(trifluoroacetamide) 685-27-8	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd
2021-07-02	N-Methylbis(trifluoroacetamide) [Trifluoroacylating Agent] 685-27-8	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd

N-Methyl-bis(trifluoroacetamide)
685-27-8
98%
Henan Aochuang Chemical Co.,Ltd.

N-Methyl-bis(trifluoroacetamide)
685-27-8
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

N-Methylbis(trifluoroacetamide) [Trifluoroacylating Agent]
685-27-8
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

N-Methyl-bis(trifluoroacetamide) Spectrum

N-Methyl-bis(trifluoroacetamide)(685-27-8)MS N-Methyl-bis(trifluoroacetamide)(685-27-8)¹HNMR N-Methyl-bis(trifluoroacetamide)(685-27-8)¹³CNMR N-Methyl-bis(trifluoroacetamide)(685-27-8)IR1 N-Methyl-bis(trifluoroacetamide)(685-27-8)Raman

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2,2,2-trifluoro-n-methyl-n-(trifluoroacetyl)acetamide N-METHYLBIS(TRIFLUOROACETAMIDE) N-METHYL-N-BIS(TRIFLUOROACETAMIDE) N,N-BIS(TRIFLUOROACETYL)METHYLAMINE N-Methylbis(Tr N-Methylbistrifluororacetamide Florists Sendranthema Extract MBTFA, N-Methyl-2,2,2-trifluoro-N-(trifluoroacetyl)acetamide, N,N-Bis(trifluoroacetyl)methylamine N,N-Bis(trifluoroacetyl)methylamine MBTFA MBTFA~N-Methyl(trifluoroacetyl)imide N-Methyl-bis-(trifluoroacetamide)(MBTFA) N-METHYLBIS(TRIFLUOROACETAMIDE), 97%, DERIVATIZATION GRADE N-METHYL-BIS(TRIFLUOROACETAMIDE)*DERIVAT IZATION GRA N-Methylbis(trifluoroacetamide) 99+% N-Methylbis(trifluoroacetamide)98% 2,2,2-Trifluoro-N-methyl-N-(2,2,2-trifluoroacetyl)acetamide N,N-Bis(trifluoroacetyl)methanamine N-Methylbis(trifluoroacetyl)amine N-Methyl-N-(trifluoroacetyl)trifluoroacetamide N-Methylbis(trifluoroacetamide)(trifluoroacylatingagent) Acetamide, 2,2,2-trifluoro-N-methyl-N-(trifluoroacetyl)- MBTFA(N-Methyl-bistrifluoroacetaMide) [Trifluoroacylating Agent] N-Methylbis(trifluoroacetaMide) MBTFA (N-methyl-bis(trifluoroacetamide)or BTFA (bis(TFA)) N-Methyl-bis(trifluoroacetamide) N,N-Bis(trifluoroacetyl)methylamine MBTFA N-Methylbis(trifluoroacetamide)[TrifluoroacylatingAgent]> Acetamide, 2,2,2-trifluoro-N-methyl-N-(2,2,2-trifluoroacetyl)- N-Methylbis(trifluoroacetyl)imide N-Methyl-bis(trifluoroacetamide)/N-Methylbis(trifluoroacetyl)imide N-Methyl-bis(trifluoroacetamide) MBTFA 685-27-8 C5H3F6NO2 CF3CONCH3COCF3 Organic Building Blocks Luminescent Compounds/Detection Luminescent conjugates Derivatization agents GC Derivatizing Reagents Acylation (GC Derivatizing Reagents) BioChemical Carbonyl Compounds Building Blocks Biochemicals and Reagents Amides Acylation Acylation Reagent Chemical Synthesis Derivatization agents Luminescent Compounds/Detection Organic Building Blocks Acylation (GC Derivatizing Reagents) Analytical Chemistry GC Derivatizing Reagents Amides Biochemicals and Reagents Building Blocks