3,4,5-Trimethoxy-α-methylbenzeneethanamine hydrochloride
- CAS No.
- 5688-80-2
- Chemical Name:
- 3,4,5-Trimethoxy-α-methylbenzeneethanamine hydrochloride
- Synonyms
- d,l-3,4,5-TMA.HCl;GOAXEHDWLMGWIV-UHFFFAOYSA-N;(±)-3,4,5-Trimethoxyamphetamine HCl (TMA);(±)-3,4,5-Trimethoxyamphetamine hydrochloride (TMA);d,l-3,4,5-TMA.HCl, 1mg/ml in Methanol (as free base);3,4,5-Trimethoxy-α-methylbenzeneethanamine hydrochloride;3,4,5-Trimethoxyamphetamine (hydrochloride) (exempt preparation)
- CBNumber:
- CB02289232
- Molecular Formula:
- C12H20ClNO3
- Molecular Weight:
- 261.745
- MDL Number:
- MOL File:
- 5688-80-2.mol
- MSDS File:
- SDS
| Melting point | 219-220 °C |
|---|---|
| solubility |
DMF: 13 mg/ml DMSO: 5 mg/ml Ethanol: 14 mg/mlPBS (pH 7.2): 10 mg/ml |
| FDA UNII | B6B7TX22VO |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS06,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H301+H311+H331-H370 | |||||||||
| Precautionary statements | P210-P240-P241-P242-P243-P260-P264-P270-P271-P280-P301+P310-P321-P330-P303+P361+P353-P304+P340-P307+P311-P312-P361+P364-P370+P378-P403+P233-P403+P235-P405-P501 | |||||||||
| NFPA 704 |
|
3,4,5-Trimethoxy-α-methylbenzeneethanamine hydrochloride price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 13887 | 3,4,5-Trimethoxyamphetamine (hydrochloride) ≥98% | 5688-80-2 | 5mg | $49 | 2026-04-30 | Buy |
| Cayman Chemical | 15682 | 3,4,5-Trimethoxyamphetamine (hydrochloride) (exempt preparation) ≥98% | 5688-80-2 | 1mg | $69 | 2026-04-30 | Buy |
| Cayman Chemical | 13887 | 3,4,5-Trimethoxyamphetamine (hydrochloride) ≥98% | 5688-80-2 | 10mg | $93 | 2026-04-30 | Buy |
| Cayman Chemical | 13887 | 3,4,5-Trimethoxyamphetamine (hydrochloride) ≥98% | 5688-80-2 | 50mg | $376 | 2026-04-30 | Buy |
| Biosynth | FAA68880 | 3,4,5-Trimethoxyamphetamine hydrochloride | 5688-80-2 | 25mg | $873.25 | 2026-06-04 | Buy |
3,4,5-Trimethoxy-α-methylbenzeneethanamine hydrochloride Chemical Properties,Uses,Production
Description
3,4,5-Trimethoxyamphetamine (TMA), is a psychedelic hallucinogen which has appeared on the illicit drug market. Unlike amphetamines and cathinones, TMA has no effect on monoamine re-uptake. TMA has modest effects on the 5-HT2 serotonin receptors (pEC50 = 5.15 and 5.31 for phosphatidyl inositol release through 5-HT2A and 5-HT2C, respectively). This product is intended for research and forensic applications.
Uses
3,4,5-Trimethoxyamphetamine (TMA), is a psychedelic hallucinogen that has appeared on the illicit drug market. Unlike amphetamines and cathinones, TMA has no effect on monoamine re-uptake. TMA has modest effects on the 5-HT2 serotonin receptors (pEC50s = 5.15 and 5.31 for phosphatidyl inositol release through 5-HT2A and 5-HT2C, respectively). This product is intended for research and forensic applications.[Cayman Chemical]
References
[1] ARIANE WOHLFARTH Sebastian D Wolfgang Weinmann. LC-MS/MS screening method for designer amphetamines, tryptamines, and piperazines in serum[J]. Analytical and Bioanalytical Chemistry, 2010, 396 7: 2403-2414. DOI: 10.1007/s00216-009-3394-4
[2] PABLO R MOYA. Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors.[J]. Journal of Pharmacology and Experimental Therapeutics, 2007, 321 3: 1054-1061. DOI: 10.1124/jpet.106.117507
[3] FUMIKO NAGAI Kanako S H K Ryouichi Nonaka. The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain[J]. European journal of pharmacology, 2007, 559 2: Pages 132-137. DOI: 10.1016/j.ejphar.2006.11.075
