|
|
| | 3,4,5-Trimethoxy-α-methylbenzeneethanamine hydrochloride Basic information |
| Product Name: | 3,4,5-Trimethoxy-α-methylbenzeneethanamine hydrochloride | | Synonyms: | 3,4,5-Trimethoxy-α-methylbenzeneethanamine hydrochloride;(±)-3,4,5-Trimethoxyamphetamine hydrochloride (TMA);3,4,5-Trimethoxyamphetamine (hydrochloride) (exempt preparation);GOAXEHDWLMGWIV-UHFFFAOYSA-N;d,l-3,4,5-TMA.HCl;(±)-3,4,5-Trimethoxyamphetamine HCl (TMA);d,l-3,4,5-TMA.HCl, 1mg/ml in Methanol (as free base) | | CAS: | 5688-80-2 | | MF: | C12H20ClNO3 | | MW: | 261.745 | | EINECS: | | | Product Categories: | | | Mol File: | 5688-80-2.mol |  |
| | 3,4,5-Trimethoxy-α-methylbenzeneethanamine hydrochloride Chemical Properties |
| Melting point | 219-220 °C | | solubility | DMF: 13 mg/ml DMSO: 5 mg/ml Ethanol: 14 mg/mlPBS (pH 7.2): 10 mg/ml |
| | 3,4,5-Trimethoxy-α-methylbenzeneethanamine hydrochloride Usage And Synthesis |
| Description | 3,4,5-Trimethoxyamphetamine (TMA), is a psychedelic hallucinogen which has appeared on the illicit drug market. Unlike amphetamines and cathinones, TMA has no effect on monoamine re-uptake. TMA has modest effects on the 5-HT2 serotonin receptors (pEC50 = 5.15 and 5.31 for phosphatidyl inositol release through 5-HT2A and 5-HT2C, respectively). This product is intended for research and forensic applications. | | Uses | 3,4,5-Trimethoxyamphetamine (TMA), is a psychedelic hallucinogen that has appeared on the illicit drug market. Unlike amphetamines and cathinones, TMA has no effect on monoamine re-uptake. TMA has modest effects on the 5-HT2 serotonin receptors (pEC50s = 5.15 and 5.31 for phosphatidyl inositol release through 5-HT2A and 5-HT2C, respectively). This product is intended for research and forensic applications.[Cayman Chemical] | | References | [1] ARIANE WOHLFARTH Sebastian D Wolfgang Weinmann. LC-MS/MS screening method for designer amphetamines, tryptamines, and piperazines in serum[J]. Analytical and Bioanalytical Chemistry, 2010, 396 7: 2403-2414. DOI: 10.1007/s00216-009-3394-4 [2] PABLO R MOYA. Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors.[J]. Journal of Pharmacology and Experimental Therapeutics, 2007, 321 3: 1054-1061. DOI: 10.1124/jpet.106.117507 [3] FUMIKO NAGAI Kanako S H K Ryouichi Nonaka. The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain[J]. European journal of pharmacology, 2007, 559 2: Pages 132-137. DOI: 10.1016/j.ejphar.2006.11.075 |
| | 3,4,5-Trimethoxy-α-methylbenzeneethanamine hydrochloride Preparation Products And Raw materials |
|