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3,5-Dimethoxytoluene

3,5-Dimethoxytoluene Structure
3,5-Dimethoxytoluene structure
CAS No.
4179-19-5
Chemical Name:
3,5-Dimethoxytoluene
Synonyms
1,3-Dimethoxy-5-methylbenzene;ORCINOL DIMETHYL ETHER;SKL305;3,5-DIMETHOXYTOLUENE;Toluene, 3,5-dimethoxy-;3,5-Dimethoxytoluene,99%;3,5-Dimethoxytoluene >3,5-DiMethoxytoluene, GC 98%;1,3-dimethoxy-5-methyl-benzen;3,5-Dimethoxy-1-methylbenzene
CBNumber:
CB0230254
Molecular Formula:
C9H12O2
Molecular Weight:
152.19
MDL Number:
MFCD00015435
MOL File:
4179-19-5.mol
MSDS File:
SDS
Last updated:2026-05-27 17:32:30
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3,5-Dimethoxytoluene Properties

Melting point 61-62 C
Boiling point 244 °C (lit.)
Density 1.039 g/mL at 25 °C (lit.)
refractive index n20/D 1.522(lit.)
Flash point 215 °F
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Sparingly), Methanol (Sparingly)
form Liquid
Specific Gravity 1.039
color Clear colorless to yellow
Odor Warm and sweet, nut-like, earthy-mossy odor
BRN 2043558
Cosmetics Ingredients Functions PERFUMING
InChI 1S/C9H12O2/c1-7-4-8(10-2)6-9(5-7)11-3/h4-6H,1-3H3
InChIKey RIZBLVRXRWHLFA-UHFFFAOYSA-N
SMILES COc1cc(C)cc(OC)c1
LogP 2.897 (est)
CAS DataBase Reference 4179-19-5(CAS DataBase Reference)
EWG's Food Scores 1
NIST Chemistry Reference 3,5-Dimethoxytoluene(4179-19-5)
EPA Substance Registry System 3,5-Dimethoxytoluene (4179-19-5)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
TSCA  TSCA listed
HS Code  29093090
Storage Class 10 - Combustible liquids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 0

3,5-Dimethoxytoluene price More Price(64)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 423742 3,5-Dimethoxytoluene 98% 4179-19-5 1g $56.3 2026-04-30 Buy
TCI Chemical D2526 3,5-Dimethoxytoluene >97.0%(GC) 4179-19-5 5g $50 2026-04-30 Buy
TCI Chemical D2526 3,5-Dimethoxytoluene >97.0%(GC) 4179-19-5 25g $198 2026-04-30 Buy
TRC TRC-D476368-5G 3,5-Dimethoxytoluene 4179-19-5 5g $72 2026-06-03 Buy
TRC TRC-D476368-25G 3,5-Dimethoxytoluene 4179-19-5 25g $177 2026-06-03 Buy
Product number Packaging Price Buy
423742 1g $56.3 Buy
D2526 5g $50 Buy
D2526 25g $198 Buy
TRC-D476368-5G 5g $72 Buy
TRC-D476368-25G 25g $177 Buy

3,5-Dimethoxytoluene Chemical Properties, Uses, Production

Chemical Properties

Clear colorless to yellow liquid

Uses

3,5-Dimethoxytoluene (DMT) may be used in the synthesis of 3,5-dimethoxybenzoic acid by oxidation and 2-methoxy-6-methyl-1,4-benzoquinone by catalytic oxidation with hydrogen peroxide (H2O2)/methyltrioxorhenium (CH3ReO3) in dimethyl carbonate (DMC).

Uses

3,5-Dimethoxytoluene has been suggested for use in perfume compositions as supporting note for Oakmoss and Vetiver, and as a novel note in Chypre, Fougere and Oriental fragrance types.

Definition

ChEBI: 3,5-dimethoxytoluene is a member of the class of toluenes that is toluene in which the hydrogens at positions 3 and 5 have been replaced by methoxy groups. It is the major scent compound of many rose varieties. It has a role as a fragrance and a plant metabolite. It is a member of toluenes and a member of methoxybenzenes.

Production Methods

3,5-Dimethoxytoluene can be produced from Orcinol in weak aqueous alkali with Dimethylsulfate at controlled temperature.

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 6, p. 859, 1988
The Journal of Organic Chemistry, 70, p. 3275, 2005 DOI: 10.1021/jo050075r

General Description

3,5-Dimethoxytoluene (DMT) is a methoxylated phenolic derivative. It is reported to be one of the main constituent of the floral volatiles in different rose varieties. It has been biosynthesized from orcinol by two successive methylation catalyzed by O-methyltransferases (OMTs). The features of its aerobic oxidation with metal/bromide catalysts have been investigated.

Synthesis

A solution of dry orcinol (14.2 g,0.115 mole) in dry anhydrous acetone(150 ml) containing anhydrous potassium carbonate (45 g) is refluxed withdimethyl sulphate (23.6 ml，31.46 g, 0.25 mole) for 4 hr. The dimethylsulphate is added in small lots of 5 ml. After refluxing, the solution isfiltered and the inorganic residue washed with hot acetone (2 x 25 ml).The combined acetone solution is distilled and the residue macerated withcrushed ice. It is extracted with ether, the ether extract dried (anhydroussodium sulphate) and distilled. Yield 14.2 g (81.6%).B.p.102° (8 mm)
3,5-Dimethoxytoluene

3,5-Dimethoxytoluene synthesis

504-15-4
4179-19-5
Synthesis of 3,5-Dimethoxytoluene from Orcinol

3,5-Dimethoxytoluene Preparation Products And Raw materials

Raw materials

Orcinol Methylmagnesium Bromide 2,6-Dimethoxy-4-methylbenzoic acid 3 5-Dimethoxyphenyl trifluoromethanesul& 5-Methylcyclohexane-1,3-dione
3,4,5-Trimethoxytoluene Methyllithium Dimethyl sulfate Iodomethane Nintedanib Impurity 65
5-Chloro-1,3-dimethoxybenzene 3,5-Dimethoxybenzyl bromide 3,5-Dimethoxybenzaldehyde 3,5-Dimethoxyphenylacetic acid trimethylammonium iodide

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Preparation Products

3-Chloro-2,6-dihydroxy-4-methylbenzaldehyde

3,5-Dimethoxytoluene Suppliers

Global Suppliers ( 197)
Supplier Tel Email Country ProdList Advantage
Xiamen Work-For-World Medcine Co., Ltd 15921822462 15921822462 keqingyong@wfwmed.com China 204 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Beijing dtftchem Technology Co., Ltd. 010-60275820 13031183356 elainezt@sina.com China 1386 62
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 45000 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11592 64
Supplier Advantage
Xiamen Work-For-World Medcine Co., Ltd 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Beijing dtftchem Technology Co., Ltd. 62
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Capot Chemical Co., Ltd 66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. 64

View Latest Price from 3,5-Dimethoxytoluene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,5-Dimethoxytoluene pictures 2026-05-11 3,5-Dimethoxytoluene
4179-19-5
 99.06% 10g TargetMol Chemicals Inc.
3,5-Dimethoxytoluene pictures 2026-04-13 3,5-Dimethoxytoluene
4179-19-5
 99% 1000KGS Zhengzhou Anbu Chem Co.,Ltd
3,5-Dimethoxytoluene pictures 2025-05-23 3,5-Dimethoxytoluene
4179-19-5
 $45.00 1kg 99% 20 tons Hebei Zhuanglai Chemical Trading Co Ltd

3,5-Dimethoxytoluene Spectrum

3,5-Dimethoxytoluene(4179-19-5)MS3,5-Dimethoxytoluene(4179-19-5)1HNMR3,5-Dimethoxytoluene(4179-19-5)13CNMR3,5-Dimethoxytoluene(4179-19-5)IR1

4179-19-5 (3,5-Dimethoxytoluene) Related Search:

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3,4,5-Trimethoxy benzoic acid 3,4,5-Trimethoxybenzaldehyde 3,4,5-Trimethoxyphenylacetic acid Colchicine 3-(3,4,5-Trimethoxyphenyl)propionic acid
3,5-Dimethoxycinnamic acid 3,5-Dimethoxybenzoyl chloride 3,4,5-Trimethoxyphenylacetonitrile

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3,5-DIMETHOXYTOLUENE 3,5-DiMethoxytoluene, GC 98% 3,5-Dimethoxy-1-methylbenzene 5-Methylresorcinol dimethyl ether Benzene, 1,3-dimethoxy-5-methyl- Toluene, 3,5-dimethoxy- 1,5-Dimethoxy-3-methylbenzene 5-Methyl-1,3-dimethoxybenzene 3,5-Dimethoxytoluene,99% 1,3-dimethoxy-5-methyl-benzen 1,3-dimethoxy-5-methyl-Benzene 3,5-Dimethoxytoluene > SKL305 3,5-Dimethoxytoluene, ≥ 97.0% Orcinol dimethyl ether|||1,3-dimethoxy-5-methylbenzene 1,3-Dimethoxy-5-methylbenzene - [D94440] 1,3-Dimethoxy-5-methylbenzene ORCINOL DIMETHYL ETHER 4179-19-5 CH3C6H3OCH32 Ethers Oxygen Compounds Organic Building Blocks Building Blocks Building Blocks C9 Aromatic Ethers Ethers Organic Building Blocks Oxygen Compounds Chemical Synthesis Organic Building Blocks Oxygen Compounds