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ChemicalBook >> CAS DataBase List >>1,2,3,6-Tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine oxalate

1,2,3,6-Tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine oxalate

1,2,3,6-Tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine oxalate Structure
1,2,3,6-Tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine oxalate structure
CAS No.
154130-99-1
Chemical Name:
1,2,3,6-Tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine oxalate
Synonyms
PD 144418;PD 144418 OXALATE;Pyridine,1,2,3,6-tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propyl-;1,2,3,6-Tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine oxalate
CBNumber:
CB02446510
Molecular Formula:
C18H22N2O
Molecular Weight:
282.38
MDL Number:
MFCD00924135
MOL File:
154130-99-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:48:00
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1,2,3,6-Tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine oxalate Properties

Boiling point 453.2±45.0 °C(Predicted)
Density 1.067±0.06 g/cm3(Predicted)
storage temp. Desiccate at RT
solubility <18.62mg/ml in DMSO
form solid
pka 8.10±0.40(Predicted)
color Off-white
FDA UNII FV9595VZB7

1,2,3,6-Tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine oxalate price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth BP177453 PD 144418 oxalate 154130-99-1 1mg $250 2026-06-04 Buy
Biosynth BP177453 PD 144418 oxalate 154130-99-1 5mg $605.35 2026-06-04 Buy
Biosynth BP177453 PD 144418 oxalate 154130-99-1 10mg $968.4 2026-06-04 Buy
ChemScene CS-0029071 PD 144418 95.42% 154130-99-1 2mg $195 2026-06-04 Buy
ChemScene CS-0029071 PD 144418 95.42% 154130-99-1 5mg $347 2026-06-04 Buy
Product number Packaging Price Buy
BP177453 1mg $250 Buy
BP177453 5mg $605.35 Buy
BP177453 10mg $968.4 Buy
CS-0029071 2mg $195 Buy
CS-0029071 5mg $347 Buy

1,2,3,6-Tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine oxalate Chemical Properties, Uses, Production

Uses

PD 144418 is high affinity, selective σ1 ligand (Ki values are 0.08 and 1377 nM for σ1 and σ2 respectively). PD 144418 displays no significant activity at a wide range of other receptors, ion channels and enzymes. PD 144418 antagonizes mescaline-induced scratching in mice following i.p. administration.

Biological Activity

High affinity, selective σ 1 ligand (K i values are 0.08 and 1377 nM for σ 1 and σ 2 respectively). Displays no significant activity at a wide range of other receptors, ion channels and enzymes. Antagonizes mescaline-induced scratching in mice following i.p. administration.

in vivo

PD 144418 (10 mg/kg; intraperitoneal injection; male CD-1 mice) treatment antagonizes Mescaline-induced scratching at doses that did not alter spontaneous motor activity, with PD 144418 showing ED50 values of 7.0 mg/kg i.p.[1].

Animal Model:Male CD-1 mice induced with Mescaline[1]
Dosage:10 mg/kg
Administration:Intraperitoneal injection
Result:Antagonized mescaline-induced scratching at doses that did not alter spontaneous motor activity.

1,2,3,6-Tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine oxalate Preparation Products And Raw materials

Raw materials

Preparation Products

1,2,3,6-Tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine oxalate Suppliers

Global Suppliers ( 37)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185 sales-cpd@caerulumpharma.com China 3493 58
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8435 60
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 sales@rrkchem.com China 57336 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
BOC Sciences +1-631-485-4226 inquiry@bocsci.com United States 19935 58
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39866 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 13675144456 sean.lv@synzest.com China 11432 58
Supplier Advantage
J & K SCIENTIFIC LTD. 76
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Chemsky (shanghai) International Co.,Ltd 60
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
EMMX Biotechnology LLC 60
Shenzhen Polymeri Biochemical Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58
BOC Sciences 58
Chongqing Chemdad Co., Ltd 58
Nanjing Shizhou Biology Technology Co.,Ltd 58

View Latest Price from 1,2,3,6-Tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine oxalate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PD 144418 pictures 2026-05-11 PD 144418
154130-99-1
 $735.00-1440.00 10g TargetMol Chemicals Inc.
1,2,3,6-TETRAHYDRO-5-[3-(4-METHYLPHENYL)-5-ISOXAZOLYL]-1-PROPYLPYRIDINE OXALATE pictures 2019-07-06 1,2,3,6-TETRAHYDRO-5-[3-(4-METHYLPHENYL)-5-ISOXAZOLYL]-1-PROPYLPYRIDINE OXALATE
154130-99-1
 $7.00 1KG 99% 100KG Career Henan Chemical Co
  • PD 144418 pictures
  • PD 144418
    154130-99-1
  • $735.00-1440.00
  • TargetMol Chemicals Inc.

154130-99-1 (1,2,3,6-Tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine oxalate) Related Search:

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PD 144418 OXALATE PD 144418 Pyridine,1,2,3,6-tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propyl- 1,2,3,6-Tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine oxalate 154130-99-1 C18H22N2OC2H2O4 Amines Aromatics Heterocycles Intermediates & Fine Chemicals Pfizer Compounds Pharmaceuticals