LEVORIN A2
- CAS No.
- 39372-30-0
- Chemical Name:
- LEVORIN A2
- Synonyms
- Candicidin D1
- CBNumber:
- CB02446732
- Molecular Formula:
- C59H84N2O18
- Molecular Weight:
- 1109.31
- MDL Number:
- MFCD01708880
- MOL File:
- 39372-30-0.mol
| Boiling point | 1273.3±65.0 °C(Predicted) |
|---|---|
| Density | 1.30±0.1 g/cm3(Predicted) |
| pka | 3.95±0.70(Predicted) |
| FDA UNII | 5190Y348H9 |
LEVORIN A2 Chemical Properties,Uses,Production
Uses
Candicidin D (CndD) is an antibiotic, which exhibits antifungal activity through interaction with steroids in cell membranes. Candicidin D inhibits S. cerevisiae, Candida albicans and other Candida spp. with MIC of 0.25-1 μg/mL in RPMI-1640 medium.
Definition
ChEBI: A 38-membered ring lactone containing seven (E)-double bonds between positions 22 and 35 and substituted by hydroxy groups at positions 9, 11, 13, 17 and 19, oxo groups at positions 3, 7 and 15, a carboxy group at position 18, a 3-amino-3, -dideoxymannopyranosyloxy group at position 21, a methyl group at position 36 and a 7-(4-aminophenyl)-5-hydroxy-4-methyl-7-oxoheptan-2-yl group at position 37. It is the major component of candicidin, a mixture of antifungal heptaene macrolides obtained fr m a strain of Streptomyces griseus.
References
[1] Borzyszkowska-Bukowska J, et al., Quest for the Molecular Basis of Improved Selective Toxicity of All-Trans Isomers of Aromatic Heptaene Macrolide Antifungal Antibiotics. Int J Mol Sci. 2021 Sep 18;22(18):10108. DOI:10.3390/ijms221810108
LEVORIN A2 Preparation Products And Raw materials
Raw materials
Preparation Products
LEVORIN A2 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Supplier | Advantage |
|---|---|
| BOC Sciences | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
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