7-Methoxy-2H-1,4-benzoxazin-3(4H)-one
- CAS No.
- 6529-94-8
- Chemical Name:
- 7-Methoxy-2H-1,4-benzoxazin-3(4H)-one
- Synonyms
- 7-methoxy-4H-1,4-benzoxazin-3-one;7-Methoxy-2H-1,4-benzoxazin-3(4H)-one;2H-1,4-Benzoxazin-3(4H)-one, 7-methoxy-;7-Methoxy-2H-benzo[b][1,4]oxazin-3(4H)-one;7-Methoxy-3,4-dihydro-2H-1,4-benzoxazin-3-one;7-methoxy-2H-benzenebenzo[b][1,4]azine-3(4H)-one
- CBNumber:
- CB02448488
- Molecular Formula:
- C9H9NO3
- Molecular Weight:
- 179.17
- MDL Number:
- MFCD06252105
- MOL File:
- 6529-94-8.mol
- MSDS File:
- SDS
| Melting point | 158-160 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3)) |
|---|---|
| Boiling point | 374.0±42.0 °C(Predicted) |
| Density | 1.245±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 12.12±0.20(Predicted) |
| Appearance | Brown to black Solid |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
7-Methoxy-2H-1,4-benzoxazin-3(4H)-one price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | GAA52994 | 7-Methoxy-2H-benzo[b][1,4]oxazin-3(4H)-one | 6529-94-8 | 5g | $649 | 2026-06-04 | Buy |
| Biosynth | GAA52994 | 7-Methoxy-2H-benzo[b][1,4]oxazin-3(4H)-one | 6529-94-8 | 10g | $778.8 | 2026-06-04 | Buy |
| Matrix Scientific | 309864 | 7-Methoxy-2H-benzo[b][1,4]oxazin-3(4H)-one | 6529-94-8 | 250.00mg | $41 | 2026-05-19 | Buy |
| Matrix Scientific | 309864 | 7-Methoxy-2H-benzo[b][1,4]oxazin-3(4H)-one | 6529-94-8 | 1.00g | $62 | 2026-05-19 | Buy |
| Matrix Scientific | 309864 | 7-Methoxy-2H-benzo[b][1,4]oxazin-3(4H)-one | 6529-94-8 | 5.00g | $278 | 2026-05-19 | Buy |
7-Methoxy-2H-1,4-benzoxazin-3(4H)-one Chemical Properties, Uses, Production
Synthesis
1268818-19-4
6529-94-8
GENERAL METHOD: 2a (2 mmol) was dissolved in acetic acid (10 mL) and powdered iron (12 mmol) was added with stirring. The reaction mixture was heated to reflux for 2 hours, during which time the progress of the reaction was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the mixture was cooled to room temperature and concentrated under reduced pressure to remove acetic acid. Ethyl acetate (EtOAc, 20 mL) was added, stirred for 2 min and filtered to remove iron impurities. The insoluble iron residue was washed with ethyl acetate (20 mL). The filtrate and washings were combined and dried with anhydrous magnesium sulfate (MgSO4). The solvent was removed by concentration under reduced pressure and the resulting crude product was purified by column chromatography to give the pure product 3a.
References
[1] Tetrahedron, 2011, vol. 67, # 6, p. 1187 - 1192
[2] European Journal of Medicinal Chemistry, 2017, vol. 132, p. 90 - 107
7-Methoxy-2H-1,4-benzoxazin-3(4H)-one Preparation Products And Raw materials
Raw materials
Preparation Products
7-Methoxy-2H-1,4-benzoxazin-3(4H)-one Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
| Shanghai Synthfine Chemical Co.,Ltd | 15921303235 | sales@synthfine.com | China | 994 | 58 |
| Shanghai Raise Chemical Technology Co.,Ltd | 15026594951 | rs@raise-chem.com | China | 4904 | 55 |
| Shanghai Xingui Biotechnology Co., Ltd. | 15121041756 | xingui2022@126.com | China | 9954 | 58 |
| Cool Pharm, Ltd | 021-60455363 18019463053 | sales@coolpharm.com | China | 8455 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
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| Amatek Scientific Co. Ltd. | 0512-56316828 400-867-5858;400-867-5858 | info@amateksci.com | China | 28760 | 58 |
| Aikon International Limited | 025-66061636 19370895928 | qqyang@aikonchem.com | China | 15810 | 58 |
| Shanghai ZiHao Pharmaceutical Co., Ltd. | 021-13482410-12 13482410112; | 362383684@qq.com | China | 751 | 58 |
