6-Chloroquinoline-2-carboxylic acid
- CAS No.
- 59394-30-8
- Chemical Name:
- 6-Chloroquinoline-2-carboxylic acid
- Synonyms
- AKOS A0602-0951;6-Chloro-2-quinolinecarboxylic acid;6-Chloroquinoline-2-carboxylic acid;2-Quinolinecarboxylic acid, 6-chloro-
- CBNumber:
- CB02451013
- Molecular Formula:
- C10H6ClNO2
- Molecular Weight:
- 207.61
- MDL Number:
- MFCD09834123
- MOL File:
- 59394-30-8.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
6-Chloroquinoline-2-carboxylic acid price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AstaTech | 50648 | 6-CHLOROQUINOLINE-2-CARBOXYLIC ACID 97% | 59394-30-8 | 0.25G | $89 | 2026-04-30 | Buy |
| AstaTech | 50648 | 6-CHLOROQUINOLINE-2-CARBOXYLIC ACID 97% | 59394-30-8 | 1G | $223 | 2026-04-30 | Buy |
| AstaTech | 50648 | 6-CHLOROQUINOLINE-2-CARBOXYLIC ACID 97% | 59394-30-8 | 5G | $774 | 2026-04-30 | Buy |
| Biosynth | JCA39430 | 6-chloroquinoline-2-carboxylic acid | 59394-30-8 | 0.5g | $336.3 | 2026-06-04 | Buy |
| Biosynth | JCA39430 | 6-chloroquinoline-2-carboxylic acid | 59394-30-8 | 5g | $1416 | 2026-06-04 | Buy |
6-Chloroquinoline-2-carboxylic acid Chemical Properties,Uses,Production
Synthesis
59394-26-2
59394-30-8
General procedure for the synthesis of 6-chloro-2-quinoline carboxylic acid from 6-chloro-2-quinoline carboxaldehyde: A solution of sodium chlorite (2.4 g) and sodium dihydrogen phosphate (2.4 g) in water (24 ml) was added slowly and dropwise over a period of 5 min to a solution of 6-chloroquinoline-2-carboxaldehyde (536 mg; 2.8 mmol) dissolved in a tert-butanol (56 ml) and 2-methyl-2-butene (14 ml) mixed solution. The reaction mixture was stirred at room temperature for 4 hours. After completion of the reaction, the organic solvent was removed by distillation under reduced pressure. Water (30 ml) was added to the residue and a white precipitate was precipitated. The precipitate was collected by filtration, washed with water and dried under vacuum in the presence of phosphorus pentoxide to afford 6-chloroquinoline-2-carboxylic acid in white powder form (505 mg; yield = 87%). Mass spectrometry/liquid chromatography analysis: m/z=208.01 (M+H), retention time=8.55 min (condition 1). NMR hydrogen spectrum (DMSO-d6,400MHz) δ: 8.41-8.39 (m, 1H, aromatic H); 8.20-8.11 (m, 3H, aromatic H); 7.82-7.79 (m, 1H, aromatic H).
References
[1] Patent: US2005/154039, 2005, A1. Location in patent: Page/Page column 11
[2] Tetrahedron, 2013, vol. 69, # 38, p. 8209 - 8215
6-Chloroquinoline-2-carboxylic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nantong Bosu Pharmaceutical Technology Co., Ltd. | 0513-51005092; 15962844273 | tashiyxy@163.com | China | 915 | 58 |
| Tianjin Anhao Biological Technology Co., Ltd. | sales@ahpharmatech.com | China | 5734 | 55 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Shanghai Pingguo Pharmaceutical Co., Ltd. | 021-20432229 | 2412110556@qq.com | China | 6016 | 55 |
| Shijiazhuang Jing Kang Technology Co.Ltd. | 13933818572 | 1519554262@qq.com | China | 1785 | 58 |
| Cochemical Ltd. | 029-86115547 17791676824 | sales@cochemical.com | China | 6736 | 58 |
| Aikon International Limited | 025-58859352 19370895928 | sales01@aikonchem.com | China | 15078 | 58 |
| Shanghai Jizhi Biochemical Technology Co. Ltd. | 021-4009004166/18616739031 18616739031 | 3007523370@qq.com | China | 40000 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| Qi Qi hang Biotechnology Co., Ltd. | 18151111370 | 1046215251@qq.com | China | 5999 | 58 |
