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(6-Chloro-1H-indol-2-yl)-methanol

(6-Chloro-1H-indol-2-yl)-methanol Structure
(6-Chloro-1H-indol-2-yl)-methanol structure
CAS No.
53590-58-2
Chemical Name:
(6-Chloro-1H-indol-2-yl)-methanol
Synonyms
1H-Indole-2-methanol, 6-chloro-;(6-Chloro-1H-indol-2-yl)-methanol
CBNumber:
CB02460372
Molecular Formula:
C9H8ClNO
Molecular Weight:
181.62
MDL Number:
MFCD09701271
MOL File:
53590-58-2.mol
MSDS File:
SDS
Last updated:2026-09-12 18:48:00
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(6-Chloro-1H-indol-2-yl)-methanol Properties

storage temp. Keep in dark place,Inert atmosphere,Room temperature

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Risk Statements  36/37/38
Safety Statements  26-36/37/39
HS Code  29339900

(6-Chloro-1H-indol-2-yl)-methanol price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA00DC31 (6-Chloro-1H-indol-2-yl)methanol 98% 53590-58-2 1g $233 2026-05-28 Buy
aablocks AA00DC31 (6-Chloro-1H-indol-2-yl)methanol 98% 53590-58-2 5g $884 2026-05-28 Buy
ACHEMBLOCK U130953 (6-chloro-1H-indol-2-yl)methanol 95% 53590-58-2 1G $380 2026-05-27 Buy
ACHEMBLOCK U130953 (6-chloro-1H-indol-2-yl)methanol 95% 53590-58-2 5G $1520 2026-05-27 Buy
Crysdot CD11109150 (6-Chloro-1H-indol-2-yl)methanol 97% 53590-58-2 5g $688 2026-05-26 Buy
Product number Packaging Price Buy
AA00DC31 1g $233 Buy
AA00DC31 5g $884 Buy
U130953 1G $380 Buy
U130953 5G $1520 Buy
CD11109150 5g $688 Buy

(6-Chloro-1H-indol-2-yl)-methanol Chemical Properties, Uses, Production

Chemical Properties

Light yellow solid

Synthesis

6-Chloroindole-2-carboxylic acid ethyl ester

27034-51-1

(6-CHLORO-1H-INDOL-2-YL)-METHANOL

53590-58-2

General procedure for the synthesis of 2-hydroxymethyl-6-chloroindole from ethyl 6-chloroindole-2-carboxylate: 2.00 g (8.94 mmol) of ethyl 6-chloroindole-2-carboxylate was dissolved in 50 ml of ethyl ether at 0°C, and 0.475 g (12.5 mmol) of lithium aluminum hydride was added slowly. The reaction mixture was heated to 45°C to reflux the reaction. Upon completion of the reaction, 10 ml of water, 10 ml of 2M aqueous sodium hydroxide solution and 10 ml of water were added sequentially at 0°C to quench the reaction. The aqueous layer was separated and extracted with tert-butyl methyl ether (3 x 100 ml). The organic layers were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure to give the crude product 2-hydroxymethyl-6-chloroindole (1.64 g; 100% yield) as a white solid. MS data: MS m/e (relative abundance): 180 ([M-H]+, 100).

References

[1] Patent: US2007/27173, 2007, A1. Location in patent: Page/Page column 112
[2] Patent: US2008/161315, 2008, A1. Location in patent: Page/Page column 15
[3] Patent: US2007/27163, 2007, A1. Location in patent: Page/Page column 22
[4] Journal of Medicinal Chemistry, 2007, vol. 50, # 6, p. 1380 - 1400
[5] Patent: US2003/144282, 2003, A1

(6-Chloro-1H-indol-2-yl)-methanol Preparation Products And Raw materials

Raw materials

Ethanol Diethyl oxalate Tetrahydrofuran Diethyl ether Lithium Aluminum Hydride
Hydrochloric acid Acetic acid Potassium 4-Chloro-2-nitrotoluene 6-Chloro-1H-indole-2-carboxylic acid methyl ester

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Preparation Products

(6-Chloro-1H-indol-2-yl)-methanol Suppliers

Global Suppliers ( 26)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Shanghai Chem-Milestone Co., Ltd 021-50273253 13641951838 chemmilestone@163.com China 149 62
Wuhan TCASChem Technology Co., Ltd. 027-86697669 13986148687 sales@tcaschem.com China 3989 55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66028182 17714375163 yftan@aikonchem.com China 16674 50
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Shanghai Anmike Chemical Co. Ltd. 微信 18019252918 18019252918 sale@amkchem.com China 9988 55
Shanghai CR Corporation Limited 13917420128 13062833949 fred.wen@crcorporation.cn China 9773 58
Shanghai Baozhi Biological Technology Co., Ltd. 13764058804 3438424070@qq.com China 384 58
Shanghai SPAR pharmaceutical technology co., LTD 021-000000 admin@jingshipharmatech.com China 9919 58
Hunan chemfish Scientific co.,ltd 85567275 15200744171 sales06@chemfish.com China 5003 58
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Shanghai Chem-Milestone Co., Ltd 62
Wuhan TCASChem Technology Co., Ltd. 55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 50
Amadis Chemical Company Limited 58
Shanghai Anmike Chemical Co. Ltd. 55
Shanghai CR Corporation Limited 58
Shanghai Baozhi Biological Technology Co., Ltd. 58
Shanghai SPAR pharmaceutical technology co., LTD 58
Hunan chemfish Scientific co.,ltd 58

53590-58-2 ((6-Chloro-1H-indol-2-yl)-methanol) Related Search:

4,6-Dichloro-1H-indole-2-carboxylic acid Ethyl 4,6-dichloroindole-2-carboxylate 6-Chloroindole-2-carboxylic acid ethyl ester 6-Chloroindole-2-carboxylic acid 6-Chloro-1H-indole-2-carboxylic acid methyl ester
alpha-Phenyl-1-(2-phenylethyl)-4-piperidinemethanol Ethyl 4,6-dichloro-3-formyl-1H-indole-2-carboxylate 6-Chloro-4-fluoro-1H-indole-2-carboxylic acid 6-Chloro-7-methyl-1H-indole-2-carboxylic acid 6,7-Dichloro-1H-indole-2-carboxylic acid ethyl ester
(Z)-2-Carboxy-4,6-dichloroindole-3-(2'-phenyl-2'-carboxy)-ene 4,6-Dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propenyl]-1H-indole-2-carboxylic acid sodium salt Ethyl 3-(2-carboxy-vinyl)-4,6-dichloro-1H-indole-2-carboxylate 6,7-Dichloro-1H-indole-2-carboxylic acid 1H-Indole-2-carboxylic acid,6-chloro-4-fluoro-3-formyl-,ethyl ester
RARECHEM AL BF 1257 1-(beta-Dimethylaminoaethyl)-2-ethoxycarbonyl-3-ethoxy-6-chlor-indol-t oluol-4-sulfonat 4,6-Dichloro-3-hydroxymethyl-1H-indole-2-carboxylic acid ethyl ester

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1H-Indole-2-methanol, 6-chloro- (6-Chloro-1H-indol-2-yl)-methanol 53590-58-2