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6-Chloroindole-2-carboxylic acid ethyl ester

6-Chloroindole-2-carboxylic acid ethyl ester structure

CAS No.: 27034-51-1

Chemical Name:: 6-Chloroindole-2-carboxylic acid ethyl ester

Synonyms: SPECS AP-283/40634148;6-CHLORO-2-INDOLECARBOXYLIC;Ethyl 6-chloroindole-2-carboxylate;Ethyl 6-Chloroindole-2-Carboxylicate;Ethyl 6-chloro-1H-indole-2-caboxylate;Ethyl6-chloroindole-2-carboxylate,97%;Ethyl 6-chloro-1H-indol-2-carboxylate;ETHYL 6-CHLORO-1H-INDOLE-2-CARBOXYLATE;6-CHLORO-2-INDOLECARBOXYLIC METHYL ESTER;6-Chlor-indol-2-carbonsaeure-aethylester

CBNumber:: CB0342977

Molecular Formula:: C11H10ClNO2

Molecular Weight:: 223.66

MDL Number:: MFCD03084731

MOL File:: 27034-51-1.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-27 17:39:53

Product description	Number	Pack Size	Price
Ethyl 6-Chloroindole-2-carboxylate 98%	OR350473	250mg	$21
Ethyl 6-Chloroindole-2-carboxylate 98%	OR350473	1g	$24
Ethyl 6-Chloroindole-2-carboxylate 98%	OR350473	5g	$36
Ethyl 6-Chloroindole-2-carboxylate 98%	OR350473	25g	$169
Ethyl 6-Chloroindole-2-carboxylate 98%	OR350473	100g	$581
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6-Chloroindole-2-carboxylic acid ethyl ester Properties

Melting point	169-171 °C
Boiling point	375.0±22.0 °C(Predicted)
Density	1.329±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
form	Solid
pka	14.11±0.30(Predicted)
Appearance	Light brown to gray Solid
CAS DataBase Reference	27034-51-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a

HS Code

2933998090

NFPA 704

	1
2		0

6-Chloroindole-2-carboxylic acid ethyl ester price More Price(44)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Apolloscientific	OR350473	Ethyl 6-Chloroindole-2-carboxylate 98%	27034-51-1	250mg	$21	2026-06-04	Buy
Apolloscientific	OR350473	Ethyl 6-Chloroindole-2-carboxylate 98%	27034-51-1	1g	$24	2026-06-04	Buy
Apolloscientific	OR350473	Ethyl 6-Chloroindole-2-carboxylate 98%	27034-51-1	5g	$36	2026-06-04	Buy
Apolloscientific	OR350473	Ethyl 6-Chloroindole-2-carboxylate 98%	27034-51-1	25g	$169	2026-06-04	Buy
Apolloscientific	OR350473	Ethyl 6-Chloroindole-2-carboxylate 98%	27034-51-1	100g	$581	2026-06-04	Buy

Product number	Packaging	Price	Buy
OR350473	250mg	$21	Buy
OR350473	1g	$24	Buy
OR350473	5g	$36	Buy
OR350473	25g	$169	Buy
OR350473	100g	$581	Buy

6-Chloroindole-2-carboxylic acid ethyl ester Chemical Properties,Uses,Production

Uses

Ethyl 6-chloroindole-2-carboxylate is an organic compound mainly used as a pharmaceutical intermediate and chemical reagent.

Synthesis

2-Propenoic acid, 2-azido-3-(4-chlorophenyl)-, ethyl ester, (2Z)-

24513-05-1

6-Chloroindole-2-carboxylic acid ethyl ester

27034-51-1

General method: 6a-d (9.2 mmol) was dissolved in toluene (150 mL) under nitrogen protection, rhodium(II) acetate dimer (203 mg, 0.46 mmol) was added, and the reaction was heated to reflux for 1-2 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure, and the resulting residue was purified by silica gel column chromatography (eluent: hexane-ethyl acetate, 25:1 to 18:1, v/v) to afford the target product ethyl 6-chloroindole-2-carboxylate (7a-d) in 51.7%-58.6% overall yields.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 6, p. 1760 - 1762
[2] Journal of Medicinal Chemistry, 1991, vol. 34, # 4, p. 1283 - 1292

6-Chloroindole-2-carboxylic acid ethyl ester synthesis

Synthesis of 6-Chloroindole-2-carboxylic acid ethyl ester from Iron and Ethyl 3-(4-chloro-2-nitrophenyl)-2-oxopropanoate

6-Chloroindole-2-carboxylic acid ethyl ester Preparation Products And Raw materials

Raw materials

Ethanol Diethyl oxalate Diethyl ether Hydrochloric acid Acetic acid

Potassium 4-Chloro-2-nitrotoluene Ethyl 3-(4-chloro-2-nitrophenyl)-2-oxopropanoate (Z)-4-(4-Chlorobenzylidene)-2-methyloxazol-5(4H)-one ethyl 2-ethoxy acrylate

3-Chlorophenylhydrazine hydrochloride Ethyl-4-Chloroindole-2-Carboxylate 5-CHLORO-2-IODOANILINE 4-Chloro-2-nitrobenzaldehyde Iron

3-Chloroaniline

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Preparation Products

6-Chloroindole-2-carboxylic acid ethyl ester Suppliers

Global( 147)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29626	60
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49906	58
career henan chemical co	+86-0371-86658258	factory@coreychem.com	China	29780	58
Hefei Hangang Pharmaceutical Technology Co., Ltd.	+8618062405514	ada@ipurechemical.com	China	10224	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 17705817739	info@dycnchem.com	China	52693	58
GIHI CHEMICALS CO.,LIMITED	+86-571-86217390; +8618058761490	info@gihichemicals.com	China	49860	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850 +86-15355479329	market18@leapchem.com	China	43303	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+86-18621343501	product@acmec-e.com	China	33301	58
Aladdin Scientific		tp@aladdinsci.com	United States	54746	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-15225627621 +86-13213167925	jiuyitime@fdachem.com	China	16505	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Hefei Hangang Pharmaceutical Technology Co., Ltd.	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
GIHI CHEMICALS CO.,LIMITED	58
HANGZHOU LEAP CHEM CO., LTD.	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
Aladdin Scientific	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58

View Lastest Price from 6-Chloroindole-2-carboxylic acid ethyl ester manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2021-08-12	6-Chloroindole-2-carboxylic acid ethyl ester 27034-51-1	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd
	2020-01-15	6-Chloroindole-2-carboxylic acid ethyl ester 27034-51-1	$1.00	1g	99%	1000KGS	Career Henan Chemical Co

6-Chloroindole-2-carboxylic acid ethyl ester
27034-51-1
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

6-Chloroindole-2-carboxylic acid ethyl ester
27034-51-1
$1.00
99%
Career Henan Chemical Co

6-Chloroindole-2-carboxylic acid ethyl ester Spectrum

6-Chloroindole-2-carboxylic acid ethyl ester(27034-51-1)¹HNMR

27034-51-1(6-Chloroindole-2-carboxylic acid ethyl ester)Related Search:

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SPECS AP-283/40634148 6-CHLOROINDOLE-2-CARBOXYLIC ACID ETHYL ESTER 6-Chloroindole-2-Carboxylic Acid Ethyl Acid Ethyl 6-chloroindole-2-carboxylate 6-CHLORO-2-INDOLECARBOXYLIC METHYL ESTER Ethyl 6-Chloroindole-2-Carboxylicate 6-CHLORO-2-INDOLECARBOXYLIC 6-Chloroindole-2-carboxylic acid ethyl ester ,99% 1H-Indole-2-carboxylic acid, 6-chloro-, ethyl ester 6-Chloro-1H-indole-2-carboxylic acid ethyl ester Ethyl 6-chloro-1H-indole-2-caboxylate 6-Chlor-indol-2-carbonsaeure-aethylester 6-chlorindole-2-carboxylic acid ethyl ester Ethyl6-chloroindole-2-carboxylate,97% 1H-Indole-2-carboxylic acid, 6-chloro-, ethyl ester (9CI, ACI) 6-chloro-1H-Indole-2-carboxylic acid ethyl ester (9CI ACI) 6-Chloroindole-2-carboxylic acid ethyl ester?New ETHYL 6-CHLORO-1H-INDOLE-2-CARBOXYLATE Ethyl 6-chloro-1H-indol-2-carboxylate 27034-51-1 C11H10ClNO2 Indole/indoline/oxindole Indole and Indoline Indole Indoles