2-Chloro-5-iodopyrazine
- CAS No.
- 1057216-55-3
- Chemical Name:
- 2-Chloro-5-iodopyrazine
- Synonyms
- 2-Chloro-5-iodopyrazine;2-Chloro-5-iodipyrazine;Pyrazine, 2-chloro-5-iodo-
- CBNumber:
- CB02470067
- Molecular Formula:
- C4H2ClIN2
- Molecular Weight:
- 240.43
- MDL Number:
- MFCD09909701
- MOL File:
- 1057216-55-3.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H335-H315-H302-H319 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
2-Chloro-5-iodopyrazine price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS30762 | 2-Chloro-5-iodopyrazine 95% | 1057216-55-3 | 1g | $73 | 2026-06-04 | Buy |
| Activate Scientific | AS30762 | 2-Chloro-5-iodopyrazine 95% | 1057216-55-3 | 5g | $257 | 2026-06-04 | Buy |
| Matrix Scientific | 072342 | 2-Chloro-5-iodopyrazine | 1057216-55-3 | 250.00mg | $693 | 2026-05-18 | Buy |
| Matrix Scientific | 072342 | 2-Chloro-5-iodopyrazine | 1057216-55-3 | 1.00g | $1498 | 2026-05-18 | Buy |
| Synthonix | C39982 | 2-Chloro-5-iodopyrazine 95% | 1057216-55-3 | 100mg | $20 | 2026-05-06 | Buy |
2-Chloro-5-iodopyrazine Chemical Properties,Uses,Production
Uses
2-Chloro-5-iodopyrazine is a pharmaceutical intermediate that has been reported in the literature to be used in the preparation of estrogen receptor covalent antagonists and orexin receptor modulators.
Application
2-Chloro-5-iodopyrazine can be used to prepare tetrasubstituted olefin compounds having the following structure. These compounds are estrogen receptor covalent antagonists. These compounds can be used to inhibit the growth of cell cultures of MCF7ER-alpha (wild-type) and MCF7ER-alpha (Y537S mutant) cells. Other compounds known to inhibit the growth of cell cultures of MCF7ER-alpha (wild-type) cells (e.g., tamoxifen, raloxifene, and fulvestrant) are currently used to treat breast cancer in human patients. Therefore, the compounds disclosed herein can be used to treat breast cancer expressing ER-alpha in human patients, and specifically, to treat breast cancer expressing Y537S mutant ER-alpha in human patients.
2-Chloro-5-iodopyrazine Preparation Products And Raw materials
Raw materials
Preparation Products
2-Chloro-5-iodopyrazine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Shanghai yirong biology science and technology co., ltd | 18049974220 | 3060526242@qq.com | China | 999 | 60 |
| Kohn & Shawn Pharmatech Co.,Ltd | 0943-8293106 | sales@kyxpharma.com | China | 297 | 55 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9513 | 58 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29985 | 65 |
| Shanghai Hong-chuang Pharma Tech Co., Ltd. | 18151128828 | hc-sales@foxmail.com | China | 2635 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
