Iodopyrazine
- CAS No.
- 32111-21-0
- Chemical Name:
- Iodopyrazine
- Synonyms
- 2-IODOPYRAZINE;IODOPYRAZINE;Iodopyrazine>Iodopyrazine 97%;Iodopyrazine,97%;Pyrazine, 2-iodo-;2-IODOPYRAZINE 97%;2-Iodopyrazine,95%;2-Iodo-1,4-diazine;2-Iodopyrazine,Iodopyrazine
- CBNumber:
- CB5386987
- Molecular Formula:
- C4H3IN2
- Molecular Weight:
- 205.98
- MDL Number:
- MFCD01319019
- MOL File:
- 32111-21-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 90 °C (decomp) |
|---|---|
| Boiling point | 109-110 °C34 mm Hg(lit.) |
| Density | 2.086 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | -0.85±0.10(Predicted) |
| form | Crystalline Powder |
| color | White to pale yellow |
| Sensitive | Light Sensitive |
| InChI | InChI=1S/C4H3IN2/c5-4-3-6-1-2-7-4/h1-3H |
| InChIKey | OYWPFIUVDKHHGQ-UHFFFAOYSA-N |
| SMILES | C1(I)=NC=CN=C1 |
| CAS DataBase Reference | 32111-21-0(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29339900 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
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| NFPA 704 |
|
Iodopyrazine price More Price(57)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 513164 | Iodopyrazine 97% | 32111-21-0 | 5g | $56.7 | 2026-04-30 | Buy |
| Sigma-Aldrich | 513164 | Iodopyrazine 97% | 32111-21-0 | 1g | $47.9 | 2023-06-20 | Buy |
| TCI Chemical | I0837 | 2-Iodopyrazine >97.0%(GC) | 32111-21-0 | 1g | $35 | 2026-04-30 | Buy |
| TCI Chemical | I0837 | 2-Iodopyrazine >97.0%(GC) | 32111-21-0 | 5g | $118 | 2026-04-30 | Buy |
| Apolloscientific | OR3669 | 2-Iodopyrazine ≥95% | 32111-21-0 | 1g | $21 | 2026-06-04 | Buy |
Iodopyrazine Chemical Properties,Uses,Production
Chemical Properties
Colorless to brown liquid
Synthesis
14508-49-7
32111-21-0
General procedure for the synthesis of 2-iodopyrazine from 2-chloropyrazine: a reaction mixture of 2-chloropyrazine (7.5 mL, 83 mmol), NaI (30.3 g, 202 mmol), HOAc (9.6 mL, 168 mmol) and H2SO4 (0.5 mL) in MeCN (105 mL) was heated and refluxed for 4.5 hours. Upon completion of the reaction, the solvent was removed under reduced pressure and water (120 mL) was added. The solution was alkalized with saturated NaHCO3 solution and extracted with dichloromethane (DCM) (2 x 125 mL). The DCM layers were combined, washed sequentially with saturated Na2S2O3 solution and brine, and dried over anhydrous Na2SO4. The solvent was removed under reduced pressure to give the crude 2-iodopyrazine as an oil (12.33 g, 20% yield, 71% purity).1H NMR analysis showed that the crude contained less than about 10 mol% of 2-chloropyrazine. Following the same procedure, another batch of 2-chloropyrazine (50 g, 437 mmol) was converted to the crude 2-iodopyrazine (~65 g). The two crude batches were combined and distilled under reduced pressure (ca. 0.75 Torr, boiling point 47 °C) to give 64 g of pure 2-iodopyrazine (60% yield).1H-NMR (CDCl3, 300 MHz) δ 8.40 (dd, J = 1.8, 2.4 Hz, 1H), 8.51 (d, J = 2.4 Hz, 1H), 8.87 (d, J = 1.5 Hz, 1H).
References
[1] Tetrahedron, 1998, vol. 54, # 33, p. 9701 - 9710
[2] Patent: WO2009/114313, 2009, A2. Location in patent: Page/Page column 15
Iodopyrazine Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Wuping Biological Technology Co., Ltd. | 18501609135 | 182517690@qq.com | China | 236 | 55 |
| Tongchuang Pharma(Suzhou). Co., Ltd. | 0512-63263366 18912765016 | tongtf110@sina.com | China | 984 | 62 |
| Fengcheng Meditech (Tianjin)Co., Ltd | 022-59002498-8008; 15122574756 | info@fcmeditech.com | China | 83 | 58 |
| Lanzhou Kangyuxin Biotechnology Co., Ltd. | 0943-8293106 | sales@kyxpharma.com | China | 3552 | 58 |
| Annular（Qihe）New Material Technology Co., Ltd | 18600642180（微信同） 13391601435 | 1584468135@qq.com | China | 2037 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| ZHIWE CHEMTECH CO LTD | 021-20221225 13917446399 | zwchem@163.com | China | 529 | 61 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
View Lastest Price from Iodopyrazine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | Iodopyrazine
32111-21-0
|
$1.10 | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2020-04-30 | Iodopyrazine
32111-21-0
|
1KG | 99.0%+ | 800 tons | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2019-07-06 | Iodopyrazine
32111-21-0
|
$1.00 | 1KG | 99% | Career Henan Chemical Co |
-
- Iodopyrazine
32111-21-0
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- Iodopyrazine
32111-21-0
- 99.0%+
- Shaanxi Dideu Medichem Co. Ltd
-
- Iodopyrazine
32111-21-0
- $1.00
- 99%
- Career Henan Chemical Co
