4-Bromophenylacetone
- CAS No.
- 6186-22-7
- Chemical Name:
- 4-Bromophenylacetone
- Synonyms
- 1-(4-BROMOPHENYL)PROPAN-2-ONE;4-BROMOPHENYLACETONE;4-BROMOPHENYLACETONATE;LABOTEST-BB LT01143429;4-Bromophenylacetone,97%;4-Bromophenylacetone,99%;4-Bromophenylacetone >4-Bromophenylacetone ,98%;P-BROMO BENZYL METHYL KETONE;1-(4-BROMOPHENYL)-2-PROPANONE
- CBNumber:
- CB0251262
- Molecular Formula:
- C9H9BrO
- Molecular Weight:
- 213.07
- MDL Number:
- MFCD00210401
- MOL File:
- 6186-22-7.mol
- MSDS File:
- SDS
| Melting point | 24-25 °C |
|---|---|
| Boiling point | 139°C/11mmHg(lit.) |
| Density | 1.3841 (rough estimate) |
| refractive index | 1.5560 to 1.5600 |
| storage temp. | Sealed in dry,Room Temperature |
| form | Liquid After Melting |
| color | Clear yellow |
| Water Solubility | Miscible with chloroform and dichloromethane. Slightly miscible with water. |
| InChI | InChI=1S/C9H9BrO/c1-7(11)6-8-2-4-9(10)5-3-8/h2-5H,6H2,1H3 |
| InChIKey | CFMMTXJMIJRUSH-UHFFFAOYSA-N |
| SMILES | C(C1=CC=C(Br)C=C1)C(=O)C |
| CAS DataBase Reference | 6186-22-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H227 | |||||||||
| Precautionary statements | P501-P210-P280-P370+P378-P403+P235 | |||||||||
| Safety Statements | 24/25 | |||||||||
| HS Code | 29143900 | |||||||||
| NFPA 704 |
|
4-Bromophenylacetone price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | B4387 | 4-Bromophenylacetone >98.0%(GC) | 6186-22-7 | 5g | $51 | 2026-04-30 | Buy |
| TCI Chemical | B4387 | 4-Bromophenylacetone >98.0%(GC) | 6186-22-7 | 25g | $179 | 2026-04-30 | Buy |
| Biosynth | FB68051 | (4-Bromophenyl)acetone | 6186-22-7 | 5g | $196.35 | 2026-06-04 | Buy |
| Biosynth | FB68051 | (4-Bromophenyl)acetone | 6186-22-7 | 25g | $628.25 | 2026-06-04 | Buy |
| Biosynth | FB68051 | (4-Bromophenyl)acetone | 6186-22-7 | 50g | $999.5 | 2026-06-04 | Buy |
4-Bromophenylacetone Chemical Properties, Uses, Production
Chemical Properties
clear light yellow liquid after melting
Uses
4-Bromophenylacetone is used to prepare biphenyl-4-yl-acetone by reacting with phenylboronic acid using cesium fluoride as a reagent and palladium phosphine complex as a catalyst.
Synthesis
21892-60-4
6186-22-7
1-Bromo-4-(2-nitroprop-1-en-1-yl)benzene (116.8 g, 0.48 mol) was mixed with iron powder (228 g, 4.08 mol) and ferric(III) chloride (2.28 g, 14 mmol) in water (456 ml), heated to 65°C and then 37% hydrochloric acid (about 20 ml) was added slowly and dropwise. The heating was stopped and the mixture was warmed up to about 95°C due to an exothermic reaction. After the exothermic reaction subsided, 37% hydrochloric acid (about 200 ml) was added slowly and stirring was continued to room temperature. Ethyl acetate (900 ml) was added and stirred for 30 minutes. The reaction mixture was filtered through a diatomaceous earth pad and layered and the aqueous phase was re-extracted with ethyl acetate (200 ml). The organic phases were combined, washed with brine and dried over magnesium sulfate. Filtration and concentration gave 2-(4-bromophenyl)acetone (96.5 g, 94% yield) as an oil, which was pure enough to be used directly in the subsequent reaction.
References
[1] Patent: WO2017/29104, 2017, A1. Location in patent: Page/Page column 11
[2] Synthesis, 1985, # 6/7, p. 654 - 656
[3] Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1978, p. 995 - 1001
[4] Chimica Therapeutica, 1968, vol. 3, p. 313 - 320
[5] Journal of the American Chemical Society, 1964, vol. 86, p. 684 - 687
4-Bromophenylacetone Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan Shengqi Pharmaceutical Co., Ltd | 0531-82687819 15610111696 | xgc01@orgachem.com | China | 176 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Thermo Fisher Scientific | 800-810-5118 | cnchemical@thermofisher.com | China | 17752 | 75 |
View Latest Price from 4-Bromophenylacetone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 4-Bromophenylacetone
6186-22-7
|
$5.00 | 1KG | 98% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-08-07 | 4-Bromophenylacetone
6186-22-7
|
$1.00-4.00 | 1KG | 99% | 200000KG | Shaanxi Dideu Medichem Co. Ltd | |
 |
2026-06-30 | 4-Bromophenylacetone
6186-22-7
|
1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd |
-
- 4-Bromophenylacetone
6186-22-7
- $5.00
- 98%
- Henan Fengda Chemical Co., Ltd
-
- 4-Bromophenylacetone
6186-22-7
- $1.00-4.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- 4-Bromophenylacetone
6186-22-7
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
