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(4-Fluorophenyl)acetone

(4-Fluorophenyl)acetone structure

CAS No.: 459-03-0

Chemical Name:: (4-Fluorophenyl)acetone

Synonyms: 4-FLUOROPHENYLACETONE;cas 459-03-0;2-Propanone, 1-(4;4'-FLUOROPHENYLACETONE;(P-FLUOROPHENYL)ACETONE;4-Fluorophenylacetone98%;4-Fluorophenylacetone 98%;4-Fluorophenylacetone,99%;1-(4-Fluorophenyl)acetone;4-Fluorophenylacetone pmk

CBNumber:: CB0459004

Molecular Formula:: C9H9FO

Molecular Weight:: 152.17

MDL Number:: MFCD00000362

MOL File:: 459-03-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-27 22:41:17

Product description	Number	Pack Size	Price
(4-Fluorophenyl)acetone 98%	209457	10g	$286
4-Fluorophenylacetone >98.0%(GC)	F0535	5g	$30
4-Fluorophenylacetone >98.0%(GC)	F0535	25g	$115
4-Fluorophenylacetone ≥98%	9003642	5mg	$63
(4-Fluorophenyl)acetone	FF23471	50g	$250
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(4-Fluorophenyl)acetone Properties

Boiling point	106-107 °C/18 mmHg (lit.)
Density	1.139 g/mL at 25 °C (lit.)
refractive index	n20/D 1.496(lit.)
Flash point	197 °F
storage temp.	Sealed in dry,Room Temperature
solubility	Methyl Acetate: 50 mg/ml
form	clear liquid
Specific Gravity	1.139
color	Light yellow to Yellow to Orange
Water Solubility	insoluble
BRN	1936697
InChI	InChI=1S/C9H9FO/c1-7(11)6-8-2-4-9(10)5-3-8/h2-5H,6H2,1H3
InChIKey	ZUEKIIWSVFBTCM-UHFFFAOYSA-N
SMILES	C(C1=CC=C(F)C=C1)C(=O)C
CAS DataBase Reference	459-03-0(CAS DataBase Reference)
NIST Chemistry Reference	(4-Fluorophenyl)acetone(459-03-0)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H227

Precautionary statements

P210-P280-P403+P235-P501-P210e-P280a-P370+P378a-P501a

PPE

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Codes

F,Xi

Risk Statements

36/37/38

Safety Statements

24/25

WGK Germany

Hazard Note

Flammable

HazardClass

IRRITANT, FLAMMABLE

HS Code

29147090

Storage Class

10 - Combustible liquids

NFPA 704

	2
0		0

(4-Fluorophenyl)acetone price More Price(58)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	209457	(4-Fluorophenyl)acetone 98%	459-03-0	10g	$286	2026-04-30	Buy
TCI Chemical	F0535	4-Fluorophenylacetone >98.0%(GC)	459-03-0	5g	$30	2026-04-30	Buy
TCI Chemical	F0535	4-Fluorophenylacetone >98.0%(GC)	459-03-0	25g	$115	2026-04-30	Buy
Cayman Chemical	9003642	4-Fluorophenylacetone ≥98%	459-03-0	5mg	$63	2026-04-30	Buy
Biosynth	FF23471	(4-Fluorophenyl)acetone	459-03-0	50g	$250	2026-06-04	Buy

Product number	Packaging	Price	Buy
209457	10g	$286	Buy
F0535	5g	$30	Buy
F0535	25g	$115	Buy
9003642	5mg	$63	Buy
FF23471	50g	$250	Buy

(4-Fluorophenyl)acetone Chemical Properties,Uses,Production

Description

This intermediate, also known as (4-Fluorophenyl)acetone, presents as a dark yellow liquid. It is known to be insoluble in water. For best results, store in a tightly closed container in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. 4-Fluorophenylacetone is incompatible with strong oxidizing agents. This chemical is a combustible liquid.

Chemical Properties

clear yellow liquid

Uses

4-Fluorophenylacetone is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields. It is a haloarylacetone derivative used in a study of reversed enantiopreference of an ω-transaminase by a single-point mutation.

Application

(4-Fluorophenyl)acetone is a phenylacetic acid derivative that inhibits the 5-HT2 receptors. It has been shown to have inhibitory activities against dopamine and serotonin by acting as an agonist at the receptor. (4-Fluorophenyl)acetone also binds to nucleophilic sites on proteins, which may lead to inhibition of protein synthesis. Brevibacterium sp. strain P7 was used as a model system and it has found that it inhibited the growth of this bacterium by binding to the enzyme RNA polymerase, preventing transcription and replication.

Synthesis

4-Fluorophenyl acetone synthesis methods are mainly the following: (1) 4-fluorophenyl derivatives and acetone in the presence of catalysts such as manganese acetate to obtain; (2) -cyanoacetone-based m-fluorobenzene and sulfuric acid reaction can also be obtained; (3) by the starting material m-fluorotoluene through the side chain of bromination, hydrolysis to obtain m-fluorobenzaldehyde, and then after the addition of reaction with nitroethane and hydrolysis to obtain.

(4-Fluorophenyl)acetone synthesis

Synthesis of (4-Fluorophenyl)acetone from Methyllithium and 4-Fluorophenylacetic acid

(4-Fluorophenyl)acetone Preparation Products And Raw materials

Raw materials

2-Propanone, 1-fluoro-1-phenyl- 3-Fluorophenylacetone 2-Fluorophenylacetone Phenylacetone Fluorobenzene

Acetone

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Preparation Products

(4-Fluorophenyl)acetone Suppliers

Global( 265)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Wuhan Aoliqisi New Material Technology Co., Ltd.	+86-13545906766; 13545906766	sales@whaop.com	China	257	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471	sales@sarms4muscle.com	China	10378	58
RongNa Biotechnology Co.,Ltd	+86-86-13583358881 +8618560316533	Brad@rongnabiotech.com	China	3374	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	14035	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21533	55
Fluoropharm Co., Ltd.	+86-0571-85586753 +86-13336034509	sales@fluoropharm.com	China	1444	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29766	58
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49906	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +86-189 4982 3763	sales@tnjchem.com	China	34526	58
Win-Win chemical CO., Limited	+86-0086-577-64498589 +86-15355981851	sales@win-winchemical.com	China	14301	58

Supplier	Advantage
Wuhan Aoliqisi New Material Technology Co., Ltd.	58
Zhejiang J&C Biological Technology Co.,Limited	58
RongNa Biotechnology Co.,Ltd	58
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Fluoropharm Co., Ltd.	60
career henan chemical co	58
CONIER CHEM AND PHARMA LIMITED	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Win-Win chemical CO., Limited	58

View Lastest Price from (4-Fluorophenyl)acetone manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-30	4-Fluorophenylacetone 459-03-0	$10.00	1ASSAYS	99%	10 ton	RongNa Biotechnology Co.,Ltd
2026-03-20	4-Fluorophenylacetone 459-03-0		1KG	99%	20 mt	Hebei Chuanghai Biotechnology Co., Ltd
2025-07-29	4-Fluorophenylacetone 459-03-0	$6.00	1kg	99%	2000KG/Month	HebeiShuoshengImportandExportco.,Ltd

4-Fluorophenylacetone
459-03-0
$10.00
99%
RongNa Biotechnology Co.,Ltd

4-Fluorophenylacetone
459-03-0
99%
Hebei Chuanghai Biotechnology Co., Ltd

4-Fluorophenylacetone
459-03-0
$6.00
99%
HebeiShuoshengImportandExportco.,Ltd

(4-Fluorophenyl)acetone Spectrum

4-Fluorophenylacetone(459-03-0)MS 4-Fluorophenylacetone(459-03-0)¹HNMR 4-Fluorophenylacetone(459-03-0)¹³CNMR 4-Fluorophenylacetone(459-03-0)IR1 4-Fluorophenylacetone(459-03-0)Raman

459-03-0((4-Fluorophenyl)acetone)Related Search:

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1-Deuteriopropan-2-one 3-Chloro-1-(4-fluorophenyl)propan-1-one Phenylacetone 2-Bromo-1-(4-fluorophenyl)-1-butanone 4-Chloro-4'-fluorobutyrophenone

3-BROMO-5-FLUOROPHENYLACETONE 3-Fluorophenylacetone97%,3-Fluorophenylacetone 97%,3-FLUOROPHENYLACETONE 2-bromo-3-fluoropropiophenone Butyrophenone 2-Fluorophenylacetone

2-Chloro-6-fluorophenylacetone 96%,2-Chloro-6-fluorophenylacetone96%,2-CHLORO-6-FLUOROPHENYLACETONE (4-Fluorophenyl)acetone 3,4-DIMETHOXY-6-FLUOROPHENYLACETONE

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(P-FLUOROPHENYL)ACETONE P-FLUORO BENZYL METHYL KETONE 4'-FLUOROPHENYLACETONE 1-(4-FLUOROPHENYL)-2-PROPANONE 1-ACETONYL-4-FLUOROBENZENE 1-(4-Fluorophenyl)acetone 2-Propanone, 1-(4-fluorophenyl)- P-FLUORO ENZYL METHYL KETONE 4-Fluorophenylacetone,99% 4-Fluorophenylacetone 98% 4-Fluorophenylacetone98% Right fluorophenyl acetone 1-(2-Oxopropyl)-4-fluorobenzene 1-(p-Fluorophenyl)-2-propanone 3-(4-Fluorophenyl)-2-propanone 4-Fluorobenzyl Methyl Ketone 4-FLUOROPHENYLACETONE FOR SYNTHESIS 1-(4-Fluorophenyl)propan-2-one, 1-(4-Fluorophenyl)-2-oxopropane 4 - fluorine phenyl acetone 4-Fluorophenylacetone (4-Fluorophenyl)acetone 2-Propanone, 1-(4 cas 459-03-0 (4-Fluorophenyl)acetone> 4-Fluorophenylacetone 459-03-0 4-Fluorophenylacetone pmk 4-FLUOROPHENYLACETONE 459-03-0 459-03-3 459-30-0 C9F1H9O1 FC6H4CH2COCH3 Building Blocks C9 Carbonyl Compounds Alphabetic Analytical Chromatography Product Catalog Analytical Standards FA - FL Organic Building Blocks Ketones Aromatic Ketones (substituted) Aromatics Intermediates & Fine Chemicals Pharmaceuticals Ketone C9 C9Alphabetic Carbonyl Compounds F FA - FL Ketones 459-03-0