(3-BroMo-pyridin-2-yl)-acetic acid ethyl ester
- CAS No.
- 197376-41-3
- Chemical Name:
- (3-BroMo-pyridin-2-yl)-acetic acid ethyl ester
- Synonyms
- Ethyl 2-(3-Bromo-2-pyridyl)acetate;Ethyl (3-bromo-2-pyridinyl)acetate;3-Bromo-2-pyridineacetic acid ethyl ester;2-Pyridineacetic acid, 3-bromo-, ethyl ester;(3-BroMo-pyridin-2-yl)-acetic acid ethyl ester
- CBNumber:
- CB02604668
- Molecular Formula:
- C9H10BrNO2
- Molecular Weight:
- 244.09
- MDL Number:
- MFCD10566269
- MOL File:
- 197376-41-3.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H315-H319 |
| Precautionary statements | P501-P261-P270-P271-P264-P280-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312 |
(3-BroMo-pyridin-2-yl)-acetic acid ethyl ester price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | XHA37641 | Ethyl 2-(3-bromopyridin-2-yl)acetate | 197376-41-3 | 5g | $413 | 2026-06-05 | Buy |
| Matrix Scientific | 204467 | Ethyl 2-(3-bromo-2-pyridyl)acetate | 197376-41-3 | 1.00g | $431 | 2026-05-18 | Buy |
| Synthonix | E22128 | ethyl 2-(3-bromopyridin-2-yl)acetate 97.0% | 197376-41-3 | 1g | $40 | 2026-05-06 | Buy |
| Synthonix | E22128 | ethyl 2-(3-bromopyridin-2-yl)acetate 97.0% | 197376-41-3 | 5g | $200 | 2026-05-06 | Buy |
| Synthonix | E22128 | ethyl 2-(3-bromopyridin-2-yl)acetate 97.0% | 197376-41-3 | 10g | $400 | 2026-05-06 | Buy |
(3-BroMo-pyridin-2-yl)-acetic acid ethyl ester Chemical Properties, Uses, Production
Synthesis
38749-79-0
105-58-8
197376-41-3
General procedure for the synthesis of ethyl 2-(3-bromo-2-pyridyl)acetate from 2-methyl-3-bromopyridine and diethyl carbonate: lithium hexamethyldisilazane (436 mL, 0.44 mmol, 1 M hexane solution) was dissolved in anhydrous ether (1 L) under nitrogen protection. 2-Methyl-3-bromopyridine (25.0 g, 0.14 mol) was slowly added and the reaction mixture was stirred at room temperature for 1 hour. Subsequently, diethyl carbonate (26.0 mL, 0.22 mol) was added dropwise and the reaction mixture continued to be stirred overnight. Upon completion of the reaction, the reaction mixture was washed three times with a half-saturated aqueous sodium chloride solution (3 x 250 mL) and the organic phase was dried with anhydrous magnesium sulfate. The solvent was removed by concentration under reduced pressure and the residue was dissolved in hexane (200 mL). The solution was filtered through a silica gel pad (10 g) and the silica gel pad was rinsed with additional hexane (100 mL). The solvent was again concentrated under reduced pressure to remove the solvent to give the crude product. The crude product was stirred under high vacuum for 1 h to remove volatile impurities, resulting in ethyl 2-(3-bromo-2-pyridyl)acetate (37.7 g) in yellow liquid form. The molecular ion peak [M + H]+ of the product was 244.1 as analyzed by LCMS.
References
[1] Organic Letters, 2016, vol. 18, # 8, p. 1713 - 1715
[2] Synthesis, 1997, # 8, p. 949 - 952
[3] Patent: WO2014/201127, 2014, A2. Location in patent: Paragraph 00567
[4] Patent: WO2016/94710, 2016, A1. Location in patent: Paragraph 0116-0117
(3-BroMo-pyridin-2-yl)-acetic acid ethyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Wuhan ariel chemical Co., LTD. | 18986259541 18986259541 | sales@3stc.com | China | 3829 | 58 |
| Shanghai Xiannuo Biotechnology Co., Ltd. | 021-50718719 13918719472 | China | 978 | 58 | |
| Shanghai Jian Chao Chemical Technology Co., Ltd. | 150-2103-5486 18017383231 | 983544897@qq.com | China | 9335 | 55 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
| Wuhan Kaymke Chemical Co., Ltd., | 027-87342388 18086026008 | sales@kaymke.com | China | 3537 | 55 |
| Shanghai Raise Chemical Technology Co.,Ltd | 15026594951 | rs@raise-chem.com | China | 4904 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Mashilabs (Shanghai) Co.,Ltd. | 19916721580 | mafarm@126.com | China | 4534 | 58 |
View Latest Price from (3-BroMo-pyridin-2-yl)-acetic acid ethyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-29 | Ethyl 2-(3-bromopyridin-2-yl)acetate
197376-41-3
|
1kg | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd |
-
- Ethyl 2-(3-bromopyridin-2-yl)acetate
197376-41-3
- 98%
- Shaanxi Dideu New Materials Co. Ltd
