3-Bromo-2-methylpyridine
- CAS No.
- 38749-79-0
- Chemical Name:
- 3-Bromo-2-methylpyridine
- Synonyms
- 3-BROMO-2-PICOLINE;3-Bromo-2,6-Pyridine DI Corboxilic Acid;3-Bromo-2-methylpyri;2-bromo-4-bromophenol;3-bromo-2-methylpridine;3-bormo-2-methylpyridine;2-METHYL-3-BROMOPYRIDINE;3-BROMO-2-METHYLPYRIDINE;2-Picoline, 3-bromo- (6CI);Pyridine, 3-bromo-2-methyl-
- CBNumber:
- CB3235391
- Molecular Formula:
- C6H6BrN
- Molecular Weight:
- 172.02
- MDL Number:
- MFCD00191224
- MOL File:
- 38749-79-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 76°C/17mm |
|---|---|
| Density | 1.495 |
| refractive index | 1.5604 |
| Flash point | 174°F |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | 3.59±0.10(Predicted) |
| form | Liquid |
| color | Clear, colorless to brown |
| InChI | InChI=1S/C6H6BrN/c1-5-6(7)3-2-4-8-5/h2-4H,1H3 |
| InChIKey | AIPWPTPHMIYYOX-UHFFFAOYSA-N |
| SMILES | C1(C)=NC=CC=C1Br |
| CAS DataBase Reference | 38749-79-0(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H315-H318-H335 | |||||||||
| Precautionary statements | P280-P301+P312+P330-P302+P352-P305+P351+P338+P310 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-37/38-41-36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36/39-36-36/37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29333990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Dam. 1 Skin Irrit. 2 STOT SE 3 |
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| NFPA 704 |
|
3-Bromo-2-methylpyridine price More Price(85)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 662720 | 3-Bromo-2-methylpyridine 97% | 38749-79-0 | 1g | $44.6 | 2026-04-30 | Buy |
| Sigma-Aldrich | 662720 | 3-Bromo-2-methylpyridine 97% | 38749-79-0 | 250mg | $30 | 2023-06-20 | Buy |
| TCI Chemical | B2962 | 3-Bromo-2-methylpyridine >98.0%(GC) | 38749-79-0 | 1g | $34 | 2026-04-30 | Buy |
| TCI Chemical | B2962 | 3-Bromo-2-methylpyridine >98.0%(GC) | 38749-79-0 | 5g | $104 | 2026-04-30 | Buy |
| Biosynth | FB15760 | 3-Bromo-2-methylpyridine | 38749-79-0 | 10g | $150 | 2026-06-04 | Buy |
3-Bromo-2-methylpyridine Chemical Properties, Uses, Production
Chemical Properties
colorless liquid
Uses
Conversion to the corresponding pyridine carboxaldehyde via peroxide initiated NBS gem-dibromination followed by hydrolysis.
Synthesis
109-06-8
38749-79-0
The general procedure for synthesizing 2-methyl-3-bromopyridine from 2-methylpyridine was as follows: 2-methylpyridine (46.6 g) was slowly added dropwise to aluminum chloride (200 g) with reference to the method of Example 182, and the mixture was stirred continuously at 100°C. Maintaining the same temperature, bromine (40.0 g) was slowly added dropwise to the mixture over a period of 1 hour, followed by continued stirring for 30 minutes. Upon completion of the reaction, the mixture was cooled and poured into ice water, followed by addition of concentrated hydrochloric acid until the mixture was acidified. The resulting solution was washed with ethyl acetate and the aqueous layer was alkalized with 8 mol/L aqueous sodium hydroxide. The alkalized aqueous layer was extracted with ether and the extract was washed with saturated brine and dried with anhydrous sodium sulfate. Subsequently, the extract was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (eluent: hexane-ether=10:1) to afford 2-methyl-3-bromopyridine as a colorless oil (yield 5.09 g, 12% yield). The structure of the product was confirmed by 1H-NMR (CDCl3): δ 2.67 (3H, s), 6.98-7.03 (1H, m), 7.78-7.82 (1H, m), 8.40-8.44 (1H, m).
References
[1] Patent: US2007/60623, 2007, A1. Location in patent: Page/Page column 50
3-Bromo-2-methylpyridine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Cool Pharm, Ltd | 021-58581007 18019463053 | sales@coolpharm.com | China | 9999 | 58 |
| Shanghai Zhiyun Biotechnology Co., Ltd | 13119135307 | China | 2766 | 58 | |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
View Latest Price from 3-Bromo-2-methylpyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 3-Bromo-2-methylpyridine
38749-79-0
|
$5.00 | 1KG | 98% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-08-20 | 3-Bromo-2-methylpyridine
38749-79-0
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2026-06-30 | 3-Bromo-2-methylpyridine
38749-79-0
|
1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd |
-
- 3-Bromo-2-methylpyridine
38749-79-0
- $5.00
- 98%
- Henan Fengda Chemical Co., Ltd
-
- 3-Bromo-2-methylpyridine
38749-79-0
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 3-Bromo-2-methylpyridine
38749-79-0
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
