(S)-4-Boc-broMoMethylMorpholine
- CAS No.
- 919286-71-8
- Chemical Name:
- (S)-4-Boc-broMoMethylMorpholine
- Synonyms
- (S)-4-Boc-broMoMethylMorpholine;(S)-4-Boc-2-broMoMethylMorpholine;N-Boc-(2S)-(bromomethyl)morpholine;(2S)-4-Boc-2-(bromomethyl)-morpholine;(S)-tert-butyl 2-(broMoMethyl)Morpholine-4-carboxylate;tert-butyl (S)-2-(bromomethyl)morpholine-4-carboxylate;tert-butyl (2S)-2-(bromomethyl)morpholine-4-carboxylate;(2S)-2-(Bromomethyl)-4-morpholinecarboxylic acid 1,1-dimethylethyl ester;4-Morpholinecarboxylic acid, 2-(bromomethyl)-, 1,1-dimethylethyl ester, (2S)-
- CBNumber:
- CB02664404
- Molecular Formula:
- C10H18BrNO3
- Molecular Weight:
- 280.16
- MDL Number:
- MFCD20489339
- MOL File:
- 919286-71-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| (S)-tert-Butyl2-(bromomethyl)morpholine-4-carboxylate | 5531AC | 250mg | $162 |
| (S)-TERT-BUTYL-2-(BROMOMETHYL)MORPHOLINE-4-CARBOXYLATE 95.00% | CCH0033495 | 5MG | $505.14 |
| (S)-TERT-BUTYL-2-(BROMOMETHYL)MORPHOLINE-4-CARBOXYLATE 95.00% | CCH0033495 | 250MG | $525 |
| (S)-tert-Butyl 2-(bromomethyl)-morpholine-4-carboxylate 95+% | 095245 | 250mg | $643 |
| (S)-tert-Butyl 2-(bromomethyl)-morpholine-4-carboxylate 95+% | 095245 | 1g | $1428 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P305+P351+P338 |
(S)-4-Boc-broMoMethylMorpholine price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AK Scientific | 5531AC | (S)-tert-Butyl2-(bromomethyl)morpholine-4-carboxylate | 919286-71-8 | 250mg | $162 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CCH0033495 | (S)-TERT-BUTYL-2-(BROMOMETHYL)MORPHOLINE-4-CARBOXYLATE 95.00% | 919286-71-8 | 5MG | $505.14 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CCH0033495 | (S)-TERT-BUTYL-2-(BROMOMETHYL)MORPHOLINE-4-CARBOXYLATE 95.00% | 919286-71-8 | 250MG | $525 | 2021-12-16 | Buy |
| Matrix Scientific | 095245 | (S)-tert-Butyl 2-(bromomethyl)-morpholine-4-carboxylate 95+% | 919286-71-8 | 250mg | $643 | 2021-12-16 | Buy |
| Matrix Scientific | 095245 | (S)-tert-Butyl 2-(bromomethyl)-morpholine-4-carboxylate 95+% | 919286-71-8 | 1g | $1428 | 2021-12-16 | Buy |
(S)-4-Boc-broMoMethylMorpholine Chemical Properties,Uses,Production
Synthesis
135065-76-8
919286-71-8
The general procedure for the synthesis of tert-butyl (S)-2-(bromomethyl)morpholine-4-carboxylate from (S)-N-Boc-2-hydroxymethylmorpholine was as follows: (S)-N-Boc-2-hydroxymethylmorpholine (6.9 g, 0.032 mol) and carbon tetrabromide (15.8 g, 0.048 mol) were dissolved in dichloromethane (100 mL) and cooled in an ice bath to 0°C. A solution of triphenylphosphine (12.2 g, 0.046 mol) in dichloromethane (100 mL) was added slowly and dropwise over 30 minutes. The reaction temperature was maintained at 0 °C with stirring for 1 h. The reaction was gradually warmed to room temperature and stirring was continued overnight. Upon completion of the reaction, the reaction solution was concentrated to 1/2 of the original volume by distillation under reduced pressure, followed by filtration of the concentrate through a pad of silica gel and elution of the target product with a hexane solution of 15% ethyl acetate as eluent. The filtrate containing the product was collected and the solvent was removed by concentration under reduced pressure to afford tert-butyl (S)-2-(bromomethyl)morpholine-4-carboxylate as a colorless oil (8 g, 90% yield). Mass spectrometry (electrospray ionization, positive ion mode) showed m/e 281 [M + H]+.
References
[1] Patent: WO2008/121685, 2008, A1. Location in patent: Page/Page column 44
[2] Patent: WO2007/6715, 2007, A1. Location in patent: Page/Page column 34; 35-36
[3] Patent: WO2007/6714, 2007, A1. Location in patent: Page/Page column 122
[4] Patent: WO2007/58850, 2007, A2. Location in patent: Page/Page column 50
(S)-4-Boc-broMoMethylMorpholine Preparation Products And Raw materials
Raw materials
Preparation Products
(S)-4-Boc-broMoMethylMorpholine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471; | sales@sarms4muscle.com | China | 10473 | 58 |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3148 | 58 |
| Suzhou ARTK Medchem Co., Ltd. | +8618118463618 | sales1@artkmedchem.com | China | 39020 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| ForeChem (Nantong) Technology Co.,Ltd. | 513-85982855 18921614129 | sales@xianxingpharm.com | China | 2722 | 61 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 15801866362; | info@topbiochem.com | China | 9520 | 58 |
| Nanjing Norris-Pharm Technology Co., Ltd | 18652989687 | sales@norris-pharm.com | China | 8878 | 55 |
| Amatek Scientific Co. Ltd. | 0512-56316828 4008675858 | sales@amateksci.com | China | 9858 | 55 |
