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4-Ethynyl-L-phenylalanine HCl

4-Ethynyl-L-phenylalanine HCl Structure
4-Ethynyl-L-phenylalanine HCl structure
CAS No.
278605-15-5
Chemical Name:
4-Ethynyl-L-phenylalanine HCl
Synonyms
4-Ethynylphenylalanine;4-Ethynyl-L-phenylalanine;L-Phenylalanine, 4-ethynyl-;4-Ethynyl-L-phenylalanine HCl;p-Ethynylphenylalanine, 10 mM in DMSO;pEthynylphenylalanine,p Ethynylphenylalanine;(S)-2-Amino-3-(4-ethynylphenyl)propanoic acid;(2S)-2-amino-3-(4-ethynylphenyl)propanoic acid
CBNumber:
CB02665148
Molecular Formula:
C11H11NO2
Molecular Weight:
189.21
MDL Number:
MFCD18252809
MOL File:
278605-15-5.mol
MSDS File:
SDS
Last updated:2026-05-27 17:37:45
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4-Ethynyl-L-phenylalanine HCl Properties

Boiling point 343.2±37.0 °C(Predicted)
Density 1.21±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: 2.22 mg/mL (11.73 mM)
form Solid
pka 2.18±0.10(Predicted)
color Off-white to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

4-Ethynyl-L-phenylalanine HCl price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0100675 p-Ethynylphenylalanine 99.93% 278605-15-5 50mg $108 2026-06-04 Buy
aablocks AA01G8GJ 4-Ethynyl-L-phenylalanine 278605-15-5 10mg $48 2026-05-30 Buy
aablocks AA01G8GJ 4-Ethynyl-L-phenylalanine 278605-15-5 25mg $64 2026-05-30 Buy
aablocks AA01G8GJ 4-Ethynyl-L-phenylalanine 278605-15-5 50mg $84 2026-05-30 Buy
Arctom HY-23460 p-Ethynylphenylalanine 99.93% 278605-15-5 50mg $95 2026-05-26 Buy
Product number Packaging Price Buy
CS-0100675 50mg $108 Buy
AA01G8GJ 10mg $48 Buy
AA01G8GJ 25mg $64 Buy
AA01G8GJ 50mg $84 Buy
HY-23460 50mg $95 Buy

4-Ethynyl-L-phenylalanine HCl Chemical Properties,Uses,Production

Uses

p-Ethynylphenylalanine (4-Ethynyl-L-phenylalanine) is a potent, selective, reversible and competitive inhibitor of tryptophan hydroxylase (TPH), with a Ki of 32.6 μM[1]. p-Ethynylphenylalanine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

in vivo

p-Ethynylphenylalanine (30 mg/kg; i.p.) decreases in 5-HT and 5-HIAA levels in the rat midbrain but not in tissue[1].
p-Ethynylphenylalanine does not inhibit the aromatic amino acid decarboxylase[1].

Animal Model:Male Sprague-Dawley rats (200 g)[1]
Dosage:30 mg/kg
Administration:Intraperitoneal injection
Result:Decreased in 5-HT and 5-HIAA levels in the rat midbrain.

References

[1] Stokes AH, et al. p-ethynylphenylalanine: a potent inhibitor of tryptophan hydroxylase. J Neurochem. 2000 May;74(5):2067-73. DOI:10.1046/j.1471-4159.2000.0742067.x

4-Ethynyl-L-phenylalanine HCl Preparation Products And Raw materials

Raw materials

Preparation Products

4-Ethynyl-L-phenylalanine HCl Suppliers

Global( 34)Suppliers
Supplier Tel Email Country ProdList Advantage
Amatek Scientific Co. Ltd. 0512-56316828 4008675858 sales@amateksci.com China 9849 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Tianjin heowns Biochemical Technology Co., Ltd. 400-6387771-6039 18920764717 sales@heowns.com China 24636 60
Shanghai Jizhi Biochemical Technology Co. Ltd. 021-4009004166/18616739031 18616739031 3007523370@qq.com China 40000 58
Beijing Minruida Technology Co., Ltd. 010-82387566 sales@mreda.com.cn China 19323 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Advanced chemblocks inc 650-6922368 650-6922368;650-6922368 sales@achemblock.com China 2988 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59929 58
Supplier Advantage
Amatek Scientific Co. Ltd. 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
Amadis Chemical Company Limited 58
Tianjin heowns Biochemical Technology Co., Ltd. 60
Shanghai Jizhi Biochemical Technology Co. Ltd. 58
Beijing Minruida Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Advanced chemblocks inc 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
Bide Pharmatech Ltd. 58

View Lastest Price from 4-Ethynyl-L-phenylalanine HCl manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
p-Ethynylphenylalanine pictures 2026-05-11 p-Ethynylphenylalanine
278605-15-5
 $34.00-80.00 99.44% 10g TargetMol Chemicals Inc.
p-Ethynylphenylalanine pictures 2026-04-27 p-Ethynylphenylalanine
278605-15-5
 $34.00-80.00 99.44% 10g TargetMol Chemicals Inc.
p-Ethynylphenylalanine pictures 2025-08-22 p-Ethynylphenylalanine
278605-15-5
 $34.00-80.00 98.04% 10g TargetMol Chemicals Inc.

4-Ethynyl-L-phenylalanine HCl Spectrum

4-Ethynyl-L-phenylalanine HCl(278605-15-5)1HNMR

278605-15-5(4-Ethynyl-L-phenylalanine HCl)Related Search:

L-Cysteine
L-Phenylalanine, 4-ethynyl- 4-Ethynyl-L-phenylalanine HCl pEthynylphenylalanine,p Ethynylphenylalanine (2S)-2-amino-3-(4-ethynylphenyl)propanoic acid (S)-2-Amino-3-(4-ethynylphenyl)propanoic acid p-Ethynylphenylalanine, 10 mM in DMSO 4-Ethynyl-L-phenylalanine 4-Ethynylphenylalanine 278605-15-5