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2-Chloro-5-(trifluoromethyl)benzyl alcohol

2-Chloro-5-(trifluoromethyl)benzyl alcohol Structure
2-Chloro-5-(trifluoromethyl)benzyl alcohol structure
CAS No.
64372-62-9
Chemical Name:
2-Chloro-5-(trifluoromethyl)benzyl alcohol
Synonyms
Jrd-1184;RARECHEM AL BD 0369;Anacetrapib intermediate;2-Chloro-5-(trifloromethyl)benzyl alcohol;4-Chloro-3-(hydroxymethyl)benzotrifluoride;2-CHLORO-5-(TRIFLUOROMETHYL)BENZYL ALCOHOL;2-chloro-5-(trifluoromethyl)Benzenemethanol;[2-chloro-5-(trifluoroMethyl)phenyl]Methanol;Benzenemethanol, 2-chloro-5-(trifluoromethyl)-;2-Chloro-5-(trifluoromethyl)benzyl alcohol, 97+%
CBNumber:
CB0282622
Molecular Formula:
C8H6ClF3O
Molecular Weight:
210.58
MDL Number:
MFCD01631469
MOL File:
64372-62-9.mol
MSDS File:
SDS
Last updated:2026-06-04 16:00:12
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2-Chloro-5-(trifluoromethyl)benzyl alcohol Properties

Melting point 57-60°C
Flash point 110°C
storage temp. Store at room temperature
form powder to crystal
color White to Almost white
InChI 1S/C8H6ClF3O/c9-7-2-1-6(8(10,11)12)3-5(7)4-13/h1-3,13H,4H2
InChIKey VEKMDPQNERMQMO-UHFFFAOYSA-N
SMILES OCc1cc(ccc1Cl)C(F)(F)F
CAS DataBase Reference 64372-62-9(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)
GHS06
Signal word  Danger
Hazard statements  H301-H315-H319-H335
Precautionary statements  P301+P310+P330-P302+P352-P305+P351+P338
target organs Respiratory system
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-22
Safety Statements  26-36
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
HazardClass  IRRITANT
PackingGroup  Ⅲ
HS Code  29062990
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Limited Quantities 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
1
2 1

2-Chloro-5-(trifluoromethyl)benzyl alcohol price More Price(50)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 714607 2-Chloro-5-(trifluoromethyl)benzyl alcohol 97% 64372-62-9 5g $33 2023-06-20 Buy
TCI Chemical C3208 2-Chloro-5-(trifluoromethyl)benzyl Alcohol 64372-62-9 5G $148 2026-04-30 Buy
TCI Chemical C3208 2-Chloro-5-(trifluoromethyl)benzyl Alcohol 64372-62-9 25G $438 2026-04-30 Buy
Apolloscientific PC0191 2-Chloro-5-(trifluoromethyl)benzyl alcohol ≥95% 64372-62-9 5g $21 2026-06-04 Buy
Apolloscientific PC0191 2-Chloro-5-(trifluoromethyl)benzyl alcohol ≥95% 64372-62-9 25g $45 2026-06-04 Buy
Product number Packaging Price Buy
714607 5g $33 Buy
C3208 5G $148 Buy
C3208 25G $438 Buy
PC0191 5g $21 Buy
PC0191 25g $45 Buy

2-Chloro-5-(trifluoromethyl)benzyl alcohol Chemical Properties, Uses, Production

Synthesis

Synthesis of 2-chloro-5-trifluoromethylbenzyl alcohol (2):

Synthetic route of 2-chloro-5-trifluoromethylbenzyl alcohol

In a 5L three-necked flask connected to a thermometer and a mechanical stirrer, 100g (0.45mol) of 2-chloro-5-trifluoromethylbenzoic acid was added, followed by 1L of tetrahydrofuran. The mixture was stirred in an ice bath at 0℃, and under N2 protection, 900mL (0.9mol) of borane-tetrahydrofuran was slowly added dropwise. After the addition was complete, the mixture was heated to reflux for 1.5h. After the reaction was complete, 6N HCl was slowly added dropwise until no more gas was released. Then, 1L of water was added, and the mixture was extracted with EtOAc (2 x 1L).

The organic phases were combined, dried over MgSO₄, and then evaporated to dryness to give a white solid, 2-chloro-5-trifluoromethylbenzyl alcohol (2), with a yield of 85%. In this method, the feed ratio of 2-chloro-5-trifluoromethylbenzoic acid : BH₃.THF = 1 : 2.

Chemical Properties

White solid

Uses

2-Chloro-5-(trifluoromethyl)benzyl alcohol is a fluorine-containing benzyl alcohol compound, which can be used as an important chemical for the synthesis of pharmaceuticals and pesticides. 2-Chloro-5-(trifluoromethyl)benzyl alcohol is an intermediate of the Cholesterol Lipid Transfer Protein (CLTP) blocking agent, Anacetrapib.

2-Chloro-5-(trifluoromethyl)benzyl alcohol Preparation Products And Raw materials

Raw materials

Preparation Products

2-Chloro-5-(trifluoromethyl)benzyl alcohol Suppliers

Global Suppliers ( 233)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
ShangHai DEMO Chemical Co.,Ltd 400-021-7337 2355568890 sales@demochem.com China 2569 57
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11592 64
Shanghai Harvest Chemical Industrial Co., Ltd. 15721252604 17321035817 sales@harvest-chem.com China 2829 64
HANGZHOU HETE CHEMICAL TECHNOLOGY CO.,LTD 571-89189769 15168342188 China 228 62
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Alfa Aesar 84
ShangHai DEMO Chemical Co.,Ltd 57
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Capot Chemical Co., Ltd 66
JinYan Chemicals(ShangHai) Co.,Ltd. 60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. 64
Shanghai Harvest Chemical Industrial Co., Ltd. 64
HANGZHOU HETE CHEMICAL TECHNOLOGY CO.,LTD 62

View Latest Price from 2-Chloro-5-(trifluoromethyl)benzyl alcohol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Chloro-5-(trifluoromethyl)benzyl alcohol pictures 2026-08-25 2-Chloro-5-(trifluoromethyl)benzyl alcohol
64372-62-9
 $2.00-5.00 1kg 99% 100kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2-Chloro-5-(trifluoromethyl)benzyl alcohol pictures 2021-08-12 2-Chloro-5-(trifluoromethyl)benzyl alcohol
64372-62-9
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
2-Chloro-5-(trifluoromethyl)benzyl alcohol pictures 2019-07-06 2-Chloro-5-(trifluoromethyl)benzyl alcohol
64372-62-9
 $1.00 1KG 99% Career Henan Chemical Co

2-Chloro-5-(trifluoromethyl)benzyl alcohol Spectrum

2-Chloro-5-(trifluoromethyl)benzyl alcohol(64372-62-9)1HNMR

64372-62-9 (2-Chloro-5-(trifluoromethyl)benzyl alcohol) Related Search:

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