ChemicalBook >> CAS DataBase List >>2-Chloro-5-trifluoromethylpyridine

2-Chloro-5-trifluoromethylpyridine

CAS No.
52334-81-3
Chemical Name:
2-Chloro-5-trifluoromethylpyridine
Synonyms
2-CHLORO-5-(TRIFLUOROMETHYL)PYRIDINE;5-CTF;2,5-CTF;oro-5-(trifL;TIMTEC-BB SBB006728;2-Chloro-5-trifluoro;2-Chloro-5-(Trifluoromethyl)Py;2 - chloro - 5-3 Methyl pyridine;Hexadecanedioic Acid Impurity 20;2-Chlor-5-(trifluormethyl)pyridin
CBNumber:
CB4315124
Molecular Formula:
C6H3ClF3N
Molecular Weight:
181.54
MDL Number:
MFCD00042225
MOL File:
52334-81-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 04:09:24

2-Chloro-5-trifluoromethylpyridine Properties

Melting point 32-34 °C(lit.)
Boiling point 152 °C
Density 1.417 g/mL at 25 °C(lit.)
Flash point >230 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form Crystalline Low Melting Solid
pka -2.57±0.10(Predicted)
color White to yellow
Specific Gravity 1.417
BRN 3649688
InChI InChI=1S/C6H3ClF3N/c7-5-2-1-4(3-11-5)6(8,9)10/h1-3H
InChIKey JFZJMSDDOOAOIV-UHFFFAOYSA-N
SMILES C1(Cl)=NC=C(C(F)(F)F)C=C1
CAS DataBase Reference 52334-81-3(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII C9G66D966B
EPA Substance Registry System Pyridine, 2-chloro-5-(trifluoromethyl)- (52334-81-3)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi,Xn,T,F
Risk Statements  36/37/38-20/21/22-25-11
Safety Statements  26-37/39-36/37/39-45-22-16
RIDADR  2811
WGK Germany  3
RTECS  US7530000
Hazard Note  Irritant
TSCA  T
HazardClass  6.1
PackingGroup  III
HS Code  29339900
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
REACH Registrations Inactive
NFPA 704
1
2 0

2-Chloro-5-trifluoromethylpyridine price More Price(87)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 366137 2-Chloro-5-(trifluoromethyl)pyridine 98% 52334-81-3 10g $43.4 2026-04-30 Buy
Sigma-Aldrich 366137 2-Chloro-5-(trifluoromethyl)pyridine 98% 52334-81-3 50g $147 2026-04-30 Buy
TCI Chemical C1194 2-Chloro-5-(trifluoromethyl)pyridine >97.0%(GC) 52334-81-3 25g $31 2026-04-30 Buy
TCI Chemical C1194 2-Chloro-5-(trifluoromethyl)pyridine >97.0%(GC) 52334-81-3 100g $96 2026-04-30 Buy
Usbiological 267366 2-Chloro-5-trifluoropyridine Asreported 52334-81-3 250g $340 2026-06-03 Buy
Product number Packaging Price Buy
366137 10g $43.4 Buy
366137 50g $147 Buy
C1194 25g $31 Buy
C1194 100g $96 Buy
267366 250g $340 Buy

2-Chloro-5-trifluoromethylpyridine Chemical Properties, Uses, Production

Synthesis

2-Chloro-5-trifluoromethylpyridine can be synthesized by fluorination of 2-chloro-5-trichloromethylpyridine.

Chemical Properties

white to yellowish crystalline low melting solid

Uses

2-Chloro-5-(trifluoromethyl)pyridine may be employed as model substrate to investigate the regioexhaustive functionalization.

General Description

2-Chloro-5-(trifluoromethyl)pyridine is a chloro(trifluoromethyl) pyridine.

Global Suppliers ( 547)
Supplier Tel Email Country ProdList Advantage
Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd. 13396369453 18678026865 sdfantai@163.com China 904 58
Weifang Siyuan Chemical Co., Ltd. 0536-8888106 17663601818 2354379876@qq.com China 244 58
Hubei Yihua New Materials Technology Co., Ltd. 17754433341 18086038039 986173822@qq.com China 946 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61

View Latest Price from 2-Chloro-5-trifluoromethylpyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Chloro-5-trifluoromethylpyridine pictures 2026-08-20 2-Chloro-5-trifluoromethylpyridine
52334-81-3
$1.10 1g 99.00% 100 Tons min Dideu Industries Group Limited
2-Chloro-5-trifluoromethylpyridine pictures 2026-03-20 2-Chloro-5-trifluoromethylpyridine
52334-81-3
$1.00 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
2-Chloro-5-trifluoromethylpyridine pictures 2026-02-28 2-Chloro-5-trifluoromethylpyridine
52334-81-3
250KG 99.5% HPLC 1000Tons Shandong Jihui Chemical Co., Ltd.
2-choro-5-(trifluoromethyl) pyridine 2-chloro-5-(trifluoromethyl)-pyridin 2,5-CTF 2 - chloro - 5-3 Methyl pyridine 5-CTF 2-chlorine-5-trifluoromethyl pyridine oro-5-(trifL 2-chloride-5-(trifluoromethoxy)pyridine 2-Cchloro-5-(Trifluoromethyl)pyridine 2-Chloro-5-(trifluoromethyl)pyridine97% 2-Chloro-5-(trifluoromethyl)pyridine, 98+% 2-Chloro-5-(Trifluoromethyl)Py 2-CHLORO-5-TRIFLUOROMETHYLPYRIDINE 98.0% 2-Chloro-5-Tirfluoromethyl Pyridine 2-Chloro-5-trifluoro 2-Chloro-5-(trifluoroMethyl)pyridine, 98+% 25GR 5-TrifluoroMethyl-2-chloropyridine TIMTEC-BB SBB006728 PYRIDINE, 2-CHLORO-5-(TRIFLUOROMETHYL)- 6-Chloro-alpha,alpha,alpha-trifluoro-3-picoline 2-Chloro-5-TriflouroMethyl Pyridine 2-Chloro-5-(trifluoromethyl)pyridine > 2-Chloro-5-trifluoromethylpyridine ISO 9001:2015 REACH 2-Chlor-5-(trifluormethyl)pyridin Benzenesulfonylchloride,2-methoxy-4,10-dimethyl- Hexadecanedioic Acid Impurity 20 2-CHLORO-5-(TRIFLUOROMETHYL)PYRIDINE 52334-81-3 52337-81-3 5234-81-3 690341-12-4 HETERO CHLORIDE Building Blocks Halopyridines Chloropyridines Pyridines Heterocyclic Building Blocks Halogenated Heterocycles Fluorine series API Intermediate Chloropyridines Halopyridines C6Heterocyclic Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Pyridines, Pyrimidines, Purines and Pteredines Pyridine series Halides Pyridines derivates blocks FluoroCompounds Pyridines Pyridine bc0001