4-Fluorobenzyl chloride
- CAS No.
- 352-11-4
- Chemical Name:
- 4-Fluorobenzyl chloride
- Synonyms
- JACS-352-11-4;Benzyl for CFCs;AKOS BBS-00003856;p-Fluorbenzylchlorid;alpha-Chloro-p-fluor;Fluorobenzyl chlorid;p-fluorochlorobenzyl;P-FLUOROBENZYL CHLORIDE;4-FLUOROBENZYL CHLORIDE;-Chloro-p-fluorotoluene
- CBNumber:
- CB7166866
- Molecular Formula:
- C7H6ClF
- Molecular Weight:
- 144.57
- MDL Number:
- MFCD00000913
- MOL File:
- 352-11-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4-Fluorobenzyl chloride 99% | F8004 | 25g | $45.2 |
| 4-Fluorobenzyl chloride 99% | F8004 | 100g | $74.1 |
| 4-Fluorobenzyl Chloride >98.0%(GC) | F0204 | 25g | $70 |
| 4-Fluorobenzyl Chloride >98.0%(GC) | F0204 | 500g | $443 |
| p-FluorobenzylChloride | F588360 | 10g | $110 |
| More product size | |||
| Melting point | -18 °C |
|---|---|
| Boiling point | 82 °C26 mm Hg(lit.) |
| Density | 1.207 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 141 °F |
| storage temp. | Store below +30°C. |
| solubility | Chloroform (Slightly), Hexanes (Slightly) |
| form | Powder or Crystals |
| Specific Gravity | 1.207 |
| color | Yellow |
| explosive limit | 1.30%(V) |
| Water Solubility | 417mg/L(temperature not stated) |
| Sensitive | Lachrymatory |
| BRN | 742272 |
| InChI | 1S/C7H6ClF/c8-5-6-1-3-7(9)4-2-6/h1-4H,5H2 |
| InChIKey | IZXWCDITFDNEBY-UHFFFAOYSA-N |
| SMILES | Fc1ccc(CCl)cc1 |
| CAS DataBase Reference | 352-11-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzene, 1-(chloromethyl)-4-fluoro-(352-11-4) |
| EPA Substance Registry System | Benzene, 1-(chloromethyl)-4-fluoro- (352-11-4) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314 | |||||||||
| Precautionary statements | P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405 | |||||||||
| PPE | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 34-22 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| RIDADR | UN 2920 8/PG 2 | |||||||||
| WGK Germany | 2 | |||||||||
| F | 19 | |||||||||
| Hazard Note | Corrosive/Lachrymatory | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29036990 | |||||||||
| Storage Class | 8A - Combustible corrosive hazardous materials | |||||||||
| Hazard Classifications | Skin Corr. 1B | |||||||||
| Limited Quantities | 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
4-Fluorobenzyl chloride price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | F8004 | 4-Fluorobenzyl chloride 99% | 352-11-4 | 25g | $45.2 | 2026-04-30 | Buy |
| Sigma-Aldrich | F8004 | 4-Fluorobenzyl chloride 99% | 352-11-4 | 100g | $74.1 | 2026-04-30 | Buy |
| TCI Chemical | F0204 | 4-Fluorobenzyl Chloride >98.0%(GC) | 352-11-4 | 25g | $70 | 2026-04-30 | Buy |
| TCI Chemical | F0204 | 4-Fluorobenzyl Chloride >98.0%(GC) | 352-11-4 | 500g | $443 | 2026-04-30 | Buy |
| TRC | F588360 | p-FluorobenzylChloride | 352-11-4 | 10g | $110 | 2021-12-16 | Buy |
4-Fluorobenzyl chloride Chemical Properties,Uses,Production
Chemical Properties
clear colorless to slightly yellow liquid
Uses
p-Fluorobenzyl Chloride is a chemical intermediate in the synthesis of various pharmaceutical and agricultural goods.
Synthesis
Photocatalyst: nanosilver/silver chloride surface plasma composite;
Substrate: p-fluorotoluene; Halogenator: potassium chloride;
(1) 50 ml of water, 7 g of sodium chloride and 2.5 ml of hydrochloric acid (mass fraction 35%) were added in a photocatalytic reactor, respectively, and dissolved with stirring;
(2) then add 0.3 g of nanosilver/silver chloride as a photocatalyst (nanosilver loading 8.5 mol%) and 0.05 g of tetrabutylammonium chloride as a phase-transfer catalyst, and finally add 15 ml of p-fluorotoluene; the loading is the molar amount of nanoprecious metals as a molar percentage of the total amount of nanoprecious metal/semiconductor surface plasmonic composite.
(3) Under strong magnetic stirring, then turn on 300W xenon lamp irradiation, and react for 5h at room temperature;
(4) Filtering to recover the catalyst, separating out the organic phase and recycling the aqueous phase for reuse. Samples were analyzed by GS, the conversion rate of p-fluorotoluene was 36%, and no polychlorinated products were detected. Distillation to collect 180.5-182 fraction, got 4-fluorobenzyl chloride, yield 89%.
4-Fluorobenzyl chloride Preparation Products And Raw materials
Raw materials
Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5235 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Shandong Huisheng Import & Export Co., Ltd. | +86-13176845580 | da@zhongda-biotech.com | China | 232 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 973 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20124 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13843 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21590 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29819 | 58 |
View Lastest Price from 4-Fluorobenzyl chloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-09-25 | 4-Fluorobenzyl chloride
352-11-4
|
US $100.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
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2025-06-27 | 4-Fluorobenzyl chloride
352-11-4
|
US $30.00-10.00 / KG | 50KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd | |
![]() |
2025-06-20 | 4-Fluorobenzyl chloride
352-11-4
|
US $15.00-1.00 / kg | 1kg | 0.99 | 20 tons | Hebei Yanxi Chemical Co., Ltd. |
-

- 4-Fluorobenzyl chloride
352-11-4
- US $100.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-

- 4-Fluorobenzyl chloride
352-11-4
- US $30.00-10.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-

- 4-Fluorobenzyl chloride
352-11-4
- US $15.00-1.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
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