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4-Fluorobenzyl chloride

CAS No.
352-11-4
Chemical Name:
4-Fluorobenzyl chloride
Synonyms
JACS-352-11-4;Benzyl for CFCs;AKOS BBS-00003856;p-Fluorbenzylchlorid;alpha-Chloro-p-fluor;Fluorobenzyl chlorid;p-fluorochlorobenzyl;P-FLUOROBENZYL CHLORIDE;4-FLUOROBENZYL CHLORIDE;-Chloro-p-fluorotoluene
CBNumber:
CB7166866
Molecular Formula:
C7H6ClF
Molecular Weight:
144.57
MDL Number:
MFCD00000913
MOL File:
352-11-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:59:07
Product description Number Pack Size Price
4-Fluorobenzyl chloride 99% F8004 25g $45.2
4-Fluorobenzyl chloride 99% F8004 100g $74.1
4-Fluorobenzyl Chloride >98.0%(GC) F0204 25g $70
4-Fluorobenzyl Chloride >98.0%(GC) F0204 500g $443
p-FluorobenzylChloride F588360 10g $110
More product size

4-Fluorobenzyl chloride Properties

Melting point -18 °C
Boiling point 82 °C26 mm Hg(lit.)
Density 1.207 g/mL at 25 °C(lit.)
refractive index n20/D 1.513(lit.)
Flash point 141 °F
storage temp. Store below +30°C.
solubility Chloroform (Slightly), Hexanes (Slightly)
form Powder or Crystals
Specific Gravity 1.207
color Yellow
explosive limit 1.30%(V)
Water Solubility 417mg/L(temperature not stated)
Sensitive Lachrymatory
BRN 742272
InChI 1S/C7H6ClF/c8-5-6-1-3-7(9)4-2-6/h1-4H,5H2
InChIKey IZXWCDITFDNEBY-UHFFFAOYSA-N
SMILES Fc1ccc(CCl)cc1
CAS DataBase Reference 352-11-4(CAS DataBase Reference)
NIST Chemistry Reference Benzene, 1-(chloromethyl)-4-fluoro-(352-11-4)
EPA Substance Registry System Benzene, 1-(chloromethyl)-4-fluoro- (352-11-4)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405
PPE Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes  C
Risk Statements  34-22
Safety Statements  26-36/37/39-45
RIDADR  UN 2920 8/PG 2
WGK Germany  2
19
Hazard Note  Corrosive/Lachrymatory
TSCA  TSCA listed
HazardClass  8
PackingGroup  III
HS Code  29036990
Storage Class 8A - Combustible corrosive hazardous materials
Hazard Classifications Skin Corr. 1B
Limited Quantities 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
NFPA 704
2
3 0

4-Fluorobenzyl chloride price More Price(37)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich F8004 4-Fluorobenzyl chloride 99% 352-11-4 25g $45.2 2026-04-30 Buy
Sigma-Aldrich F8004 4-Fluorobenzyl chloride 99% 352-11-4 100g $74.1 2026-04-30 Buy
TCI Chemical F0204 4-Fluorobenzyl Chloride >98.0%(GC) 352-11-4 25g $70 2026-04-30 Buy
TCI Chemical F0204 4-Fluorobenzyl Chloride >98.0%(GC) 352-11-4 500g $443 2026-04-30 Buy
TRC F588360 p-FluorobenzylChloride 352-11-4 10g $110 2021-12-16 Buy
Product number Packaging Price Buy
F8004 25g $45.2 Buy
F8004 100g $74.1 Buy
F0204 25g $70 Buy
F0204 500g $443 Buy
F588360 10g $110 Buy

4-Fluorobenzyl chloride Chemical Properties,Uses,Production

Chemical Properties

clear colorless to slightly yellow liquid

Uses

p-Fluorobenzyl Chloride is a chemical intermediate in the synthesis of various pharmaceutical and agricultural goods.

Synthesis

Photocatalyst: nanosilver/silver chloride surface plasma composite;
Substrate: p-fluorotoluene; Halogenator: potassium chloride;
(1) 50 ml of water, 7 g of sodium chloride and 2.5 ml of hydrochloric acid (mass fraction 35%) were added in a photocatalytic reactor, respectively, and dissolved with stirring;
(2) then add 0.3 g of nanosilver/silver chloride as a photocatalyst (nanosilver loading 8.5 mol%) and 0.05 g of tetrabutylammonium chloride as a phase-transfer catalyst, and finally add 15 ml of p-fluorotoluene; the loading is the molar amount of nanoprecious metals as a molar percentage of the total amount of nanoprecious metal/semiconductor surface plasmonic composite.
(3) Under strong magnetic stirring, then turn on 300W xenon lamp irradiation, and react for 5h at room temperature;
(4) Filtering to recover the catalyst, separating out the organic phase and recycling the aqueous phase for reuse. Samples were analyzed by GS, the conversion rate of p-fluorotoluene was 36%, and no polychlorinated products were detected. Distillation to collect 180.5-182 fraction, got 4-fluorobenzyl chloride, yield 89%.

459-56-3
352-11-4
Synthesis of 4-Fluorobenzyl chloride from 4-Fluorobenzyl alcohol
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View Lastest Price from 4-Fluorobenzyl chloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Fluorobenzyl chloride pictures 2025-09-25 4-Fluorobenzyl chloride
352-11-4
US $100.00-1.00 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
4-Fluorobenzyl chloride pictures 2025-06-27 4-Fluorobenzyl chloride
352-11-4
US $30.00-10.00 / KG 50KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd
4-Fluorobenzyl chloride pictures 2025-06-20 4-Fluorobenzyl chloride
352-11-4
US $15.00-1.00 / kg 1kg 0.99 20 tons Hebei Yanxi Chemical Co., Ltd.
Benzene, 1-(chloromethyl)-4-fluoro- à-chloro-4-fluorotoluene 4-Fluorobenzyl chloride 99% p-Fluorbenzylchlorid 4-FLUOROBENZYL CHLORIDE P-FLUOROBENZYL CHLORIDE 5) PARA FLUORO BENZYL CHLORIDE α-Chloro-4-fluorotoluene, 1-Chloromethyl-4-fluorobenzene ALPHA-CHLORO-P-FLUOROTOLUENE ALPHA-CHLORO-4-FLUOROTOLUENE AKOS BBS-00003856 1-CHLOROMETHYL-4-FLUOROBENZENE p-Fluorobenzyl Chloride 4-Fluorobenzyl Chloride 4-Fluorobenzyle chloride a-Chloro-4-fluorotoluene 4-Fluorobenzylchloride,99% α-Chloro-4-fluorotoluene 4-Fluorophenylmethyl chloride 4-Fluoro-1-(chloromethyl)benzene -Chloro-p-fluorotoluene Toluene, alpha-chloro-p-fluoro- A-CHLORO-P-FLUOROTOLUENE 4-Fluorobenzyl chloride,98% 4-Fluorobenzyl chloride,α-Chloro-4-fluorotoluene, 1-Chloromethyl-4-fluorobenzene alpha-Chloro-p-fluor Benzyl for CFCs 4-Fluorobenzyl chloride, 98% 25ML 4-FLUOROBENZYL CHLORIDE FOR SYNTHESIS Fluorobenzyl chlorid 1-(Chloromethyl)-4-fluorobenzene, alpha-Chloro-4-fluorotoluene The fluorine benzyl chloride -(chloromethyl)-4-fluorobenzene 1-(chloromethyl)-4-fluoro-benzen JACS-352-11-4 4-FluorobenzylChloride> α-Chloro-P-fluorotoluene 4-Fluorobenzyl chloride ISO 9001:2015 REACH alpha-Chlor-4-fluortoluol Para Fluoro Benzyl Chloride p-fluorochlorobenzyl 4-Fluorobenzyl Chloride, ≥ 98.0% Phloroglucinol Impurity 120 352-11-4 355-11-4 C7H6FCl Halogenated Hydrocarbons Organic Building Blocks Building Blocks Aryl C7 BENZYL HALIDE Fluorine series bc0001