ROSOLIC ACID
- CAS No.
- 603-45-2
- Chemical Name:
- ROSOLIC ACID
- Synonyms
- AURIN;P-ROSOLIC ACID;RosoL;AURINE;CORALLIN;CI 43800;AURIN GR;Nsc 7805;Aurin 555;Rosolic aci
- CBNumber:
- CB0296269
- Molecular Formula:
- C19H14O3
- Molecular Weight:
- 290.31
- MDL Number:
- MFCD00001624
- MOL File:
- 603-45-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| p-Rosolic acid Dye content 85% | 861324 | 25g | $140 |
| p-Rosolic acid Dye content 85% | 861324 | 100g | $483 |
| Rosolic Acid | RX0175 | 25g | $143 |
| Pararosolic Acid | A0598 | 25g | $55 |
| p-Rosolic Acid | 44935 | 1g | $35 |
| More product size | |||
| Melting point | 309°C (decompose) |
|---|---|
| Boiling point | 372.4°C (rough estimate) |
| Density | 1.2497 (rough estimate) |
| refractive index | 1.4200 (estimate) |
| storage temp. | Store at room temperature. |
| solubility | Practically insoluble in water, benzene; freely soluble in ethanol |
| pka | 6.98(at 25℃) |
| form | Crystalline Powder |
| Colour Index | 43800 |
| color | Red-brown to brownish-red |
| PH Range | 6.8(YELLOW)--8.2(RED) |
| PH | 5.0-6.8, yellow to pink |
| Water Solubility | Soluble in alcohol, sodium hydroxide, potassium hydroxide and strong acids. Insoluble in water. |
| λmax | 534.6nm, 479.5nm, 482nm |
| ε(extinction coefficient) |
≥11000 at 264-270nm in ethanol ≥50000 at 478-486nm in ethanol |
| Merck | 14,881 |
| BRN | 2055205 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Major Application | electrorheological materials, films patterning, antireflective coatings, thermochromic materials, photoresists, film patterning, recording materials, lithium battery, semiconductors, printing materials, inks, corrosion inhibitors, adhesives, drugs, detecting viable cells, treatment of Alzheimer’s disease |
| InChI | 1S/C19H14O3/c20-16-7-1-13(2-8-16)19(14-3-9-17(21)10-4-14)15-5-11-18(22)12-6-15/h1-12,20-21H |
| InChIKey | FYEHYMARPSSOBO-UHFFFAOYSA-N |
| SMILES | O=C(C=C1)C=CC1=C(C2=CC=C(O)C=C2)C3=CC=C(O)C=C3 |
| CAS DataBase Reference | 603-45-2 |
| EWG's Food Scores | 1 |
| FDA UNII | 85N4AK3JAU |
| EPA Substance Registry System | 2,5-Cyclohexadien-1-one, 4-[bis(4-hydroxyphenyl)methylene]- (603-45-2) |
| UNSPSC Code | 41116121 |
| NACRES | NA.47 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-36/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29145090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
ROSOLIC ACID price More Price(46)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 861324 | p-Rosolic acid Dye content 85% | 603-45-2 | 25g | $140 | 2026-04-30 | Buy |
| Sigma-Aldrich | 861324 | p-Rosolic acid Dye content 85% | 603-45-2 | 100g | $483 | 2026-04-30 | Buy |
| Sigma-Aldrich | RX0175 | Rosolic Acid | 603-45-2 | 25g | $143 | 2023-01-07 | Buy |
| TCI Chemical | A0598 | Pararosolic Acid | 603-45-2 | 25g | $55 | 2026-04-30 | Buy |
| Cayman Chemical | 44935 | p-Rosolic Acid | 603-45-2 | 1g | $35 | 2026-04-30 | Buy |
ROSOLIC ACID Chemical Properties,Uses,Production
Chemical Properties
red crystals or powder
Uses
activates heme oxygenase, anti-oxidative stress, inhibits DNA fragmentation
Uses
A red coloring medium made from phenol or carbolic acid. It is soluble in alcohol and ether but insoluble in water. When fabrics were steeped in this solution, the color was nonactinic and therefore safe for darkrooms, windows, and doorways. Aurin was also mixed with water-soluble gums and brushed on the backs of collodion and silver bromide gelatin plates as an antihalation layer.
Uses
Rosolic acid is used as a pH indicator in the range from 5.0 to 6.8. It acts as an intermediate in the manufacturing dyes. It is involved in the activation of heme oxygenase and in the inhibition of DNA fragmentation. It finds application in the selective isolation of coliform bacteria.
Definition
ChEBI: Aurin is a diarylmethane.
Biological Activity
The transition range of p-Rosolic acid is around pH 6.6-8.0 (Below this pH range it is yellow and above it red).
Purification Methods
It forms green crystals with a metallic luster, but the colour depends on the solvent used. When recrystallised from brine (saturated aqueous NaCl) acidified with HCl, it forms red needles, but when recrystallised from EtO/AcOH, the crystals have a beetle iridescent green colour. It has been recrystallised from Me2CO (although it dissolves slowly), methyl ethyl ketone, 80-95% AcOH and from AcOH/*C6H6. An aqueous KOH solution is golden yellow, and a 70% H2SO4 solution is deep red in colour. An alternative purification is to dissolve this triphenylmethane dye in 1.5% of aqueous NH3, filter, and heat to 70-80o, then acidify with dilute AcOH by adding it slowly with vigorous stirring, whereby the aurin separates as a brick-red powder or as purplish crystals depending on the temperature and period of heating. Filter off the solid, wash it with H2O and a little dilute AcOH, then H2O again. Stir this solid with Et2O to remove any ketones and allow it to stand overnight in the Et2O, then filter and dry it in air then in a vacuum. [Gomberg & Snow J Am Chem Soc 47 202 1925, Baines & Driver J Chem Soc 123 1216 1923, UV: Burawoy Chem Ber 64 462 1941, Beilstein 8 IV 2646.]
ROSOLIC ACID Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21588 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 18895 | 58 |
| Henan Alfa Chemical Co., Ltd | +8615838112936 | sale03@alfachem.cn | China | 9798 | 58 |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 12272 | 58 |
| SUZHOU SENFEIDA CHEMICAL CO.,LTD | +86-0512-83500002 +8618662433356 | 3899766280@qq.com | China | 26362 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43333 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33324 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 |
View Lastest Price from ROSOLIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | Rosolic Acid
603-45-2
|
$1520.00-2500.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2021-07-02 | Pararosolic Acid
603-45-2
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2019-07-06 | Aurin
603-45-2
|
$1.00 | 1kg | 95%-99% | 1000kg | Career Henan Chemical Co |
-
- Rosolic Acid
603-45-2
- $1520.00-2500.00
- TargetMol Chemicals Inc.
-
- Pararosolic Acid
603-45-2
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- Aurin
603-45-2
- $1.00
- 95%-99%
- Career Henan Chemical Co
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