Paramethasone
- CAS No.
- 53-33-8
- Chemical Name:
- Paramethasone
- Synonyms
- Cortiden;PARAMETHASONE;Picaridin Impurity 9;Paramethasone (Standard);6a-Fluoro-16a-methylprednisolone;16a-Methyl-6a-fluoroprednisolone;Halobetasol Propionate Impurity 15;6-alpha-fluoro-16-alpha-methylprednisolone;Methylprednisolone Impurity 30 (Paramethasone);1, 4-PREGNADIEN-6α-FLUORO-16α-METHYL-11β, 17, 21-TRIOL-3, 20-DIONE
- CBNumber:
- CB0301372
- Molecular Formula:
- C22H29FO5
- Molecular Weight:
- 392.46
- MDL Number:
- MFCD03695621
- MOL File:
- 53-33-8.mol
- MSDS File:
- SDS
| Melting point | 228-241°C |
|---|---|
| Boiling point | 573.5±50.0 °C(Predicted) |
| Density | 1.32±0.1 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 12.34±0.70(Predicted) |
| color | White to Pale Beige |
| CAS DataBase Reference | 53-33-8 |
| FDA UNII | VFC6ZX3584 |
| ATC code | H02AB05 |
SAFETY
Risk and Safety Statements
| Hazardous Substances Data | 53-33-8(Hazardous Substances Data) |
|---|
Paramethasone price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-P191840-25MG | Paramethasone >95%(HPLC) | 53-33-8 | 25mg | $2468 | 2026-06-03 | Buy |
| TRC | TRC-P191840-2.5MG | Paramethasone >95%(HPLC) | 53-33-8 | 2.5mg | $292 | 2026-06-03 | Buy |
| Biosynth | FP100930 | Paramethasone | 53-33-8 | 1mg | $900 | 2026-06-04 | Buy |
| Biosynth | FP100930 | Paramethasone | 53-33-8 | 5mg | $1178.75 | 2026-06-04 | Buy |
| Biosynth | FP100930 | Paramethasone | 53-33-8 | 10mg | $1886 | 2026-06-04 | Buy |
Paramethasone Chemical Properties, Uses, Production
Originator
Haldrone,Lilly,US,1961
Uses
Paramethasone, is a fluorinated glucocorticoid, having anti-inflammatory and immunosuppressant properties.
Uses
Glucocorticoid.
Definition
ChEBI: Paramethasone is a fluorinated steroid.
Manufacturing Process
A solution of 0.144 g of the 3-ethylene glycol ketal of 5α,11β,17α,21 tetrahydroxy-6β-fluoro-16α-methylallopregnane-3,20-dione-21 acetate in 12 ml of chloroform and 0.1 ml of absolute alcohol was cooled to -10°C in an icesalt bath and a stream of anhydrous hydrochloric acid was gently bubbled through the solution for 2.5 hours while the temperature was maintained between -5°C and -15°C. The solution was then diluted with 25 ml of chloroform, washed with dilute sodium bicarbonate and water, dried over anhydrous sodium sulfate, and evaporated to dryness under reduced pressure at 60°C or less to give 6α-fluoro-11β,17α,21-trihydroxy-16α-methyl-4-pregnene3,20-dione 21-acetate.
brand name
Haldrone (Lilly).
Therapeutic Function
Glucocorticoid
Paramethasone Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Guangzhou Younan Technology Co., Ltd | 020-82000279 18988941452 | YN_research@163.com | China | 2984 | 58 |
| Guangzhou Ruidi Biotechnology Co., Ltd. | 020-82099279 18988941402 | sales@ubiochem.com | China | 10000 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| LGM Pharma | 1-(800)-881-8210 | inquiries@lgmpharma.com | United States | 2110 | 70 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| S.Z. PhyStandard Bio-Tech. Co., Ltd. | 0755-4000505016 13380397412 | 3001272453@qq.com | China | 5000 | 50 |
| Quality Control Solutions Ltd. | 0755-66853366 13670046396 | orders@qcsrm.com | China | 18188 | 56 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9909 | 65 |
| Chengdu Ainahua Chemicals Co., Ltd. | 028-86612776; 13699069380 | 515238037@qq.com | China | 970 | 55 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
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