2-(4-Iodo-1H-pyrazol-1-yl)ethanol
- CAS No.
- 1408334-75-7
- Chemical Name:
- 2-(4-Iodo-1H-pyrazol-1-yl)ethanol
- Synonyms
- 4-Iodo-1H-pyrazole-1-ethanol;2-(4-iodopyrazol-1-yl)ethanol;1H-Pyrazole-1-ethanol, 4-iodo-;2-(4-Iodo-1H-pyrazol-1-yl)ethanol
- CBNumber:
- CB03042122
- Molecular Formula:
- C5H7IN2O
- Molecular Weight:
- 238.03
- MDL Number:
- MOL File:
- 1408334-75-7.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P280-P305+P351+P338-P310 |
2-(4-Iodo-1H-pyrazol-1-yl)ethanol price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Synthonix | K41137 | 2-(4-Iodo-1H-pyrazol-1-yl)ethanol 98% | 1408334-75-7 | 100mg | $20 | 2026-05-06 | Buy |
| Synthonix | K41137 | 2-(4-Iodo-1H-pyrazol-1-yl)ethanol 98% | 1408334-75-7 | 250mg | $25 | 2026-05-06 | Buy |
| Synthonix | K41137 | 2-(4-Iodo-1H-pyrazol-1-yl)ethanol 98% | 1408334-75-7 | 1g | $60 | 2026-05-06 | Buy |
| Synthonix | K41137 | 2-(4-Iodo-1H-pyrazol-1-yl)ethanol 98% | 1408334-75-7 | 5g | $270 | 2026-05-06 | Buy |
| aablocks | AA001CS5 | 2-(4-Iodo-1H-pyrazol-1-yl)ethanol 98% | 1408334-75-7 | 100mg | $9 | 2026-05-28 | Buy |
2-(4-Iodo-1H-pyrazol-1-yl)ethanol Chemical Properties, Uses, Production
Synthesis
3469-69-0
540-51-2
1408334-75-7
General procedure: preparation of 2-(4-iodo-1H-pyrazol-1-yl)ethanol 4-Iodo-1H-pyrazole (4.50 g, 23.20 mmol) was dissolved in N,N-dimethylformamide (DMF, 45 mL), and sodium hydride (60% w/w, 1.42 g, 35.5 mmol) was added at 0 °C and stirred at room temperature for 1 hour. Subsequently, 2-bromoethanol (2.5 mL, 35.2 mmol) was added dropwise to the reaction mixture at 0 °C. The reaction system was warmed up to 65 °C and stirred continuously for 3 days. Upon completion of the reaction, the reaction was quenched with saturated sodium chloride solution and ethyl acetate (EtOAc) and the aqueous phase was extracted with ethyl acetate. The organic phases were combined, washed sequentially with water and saturated sodium chloride solution, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The residue was purified by silica gel column chromatography using cyclohexane/ethyl acetate (0 to 50% gradient) as eluent to afford the target compound 2-(4-iodo-1H-pyrazol-1-yl)ethanol (3.55 g, 64% yield). 1H NMR (500 MHz, CDCl3): δ 7.55 (s, 1H), 7.52 (s, 1H), 4.32-4.22 (m, 2H), 4.04-3.95 (m, 2H), 2.79-2.68 (br m, 1H). LCMS (ESI) Rt = 1.50 min, MS m/z 238 [M + H]+.
References
[1] Patent: WO2014/37750, 2014, A1. Location in patent: Paragraph 00142-00144
2-(4-Iodo-1H-pyrazol-1-yl)ethanol Preparation Products And Raw materials
Raw materials
Preparation Products
2-(4-Iodo-1H-pyrazol-1-yl)ethanol Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
| Shanghai Jiyi Biological Technology Co., LTD | 021-54135696 18516235431 | shgegenetech@163.com | China | 469 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Cool Pharm, Ltd | 021-60455363 18019463053 | sales@coolpharm.com | China | 8455 | 58 |
| BePharm Ltd | 400-685-9117 | market@bepharm.com | China | 15081 | 60 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Taian Jiaye Biotechnology Co.Ltd | 15318151873;13127280945 | 285424065@qq.com | China | 9961 | 55 |
| Aikon International Limited | 025-58859352 19370895928 | sales01@aikonchem.com | China | 15078 | 58 |
| SHANGHAI FDC-CHEMICAL CO.,LTD | 021-61469567 13774476675 | sales@fdc-chemical.com | China | 10000 | 58 |
| Yujinpharma(Tianjin) Technology Co.,Ltd. | 13370351217 kungfu1217@1 | kungfu1217@163.com | China | 7991 | 58 |
