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Bromo-PEG4-t-butyl ester

Bromo-PEG4-t-butyl ester structure

CAS No.: 564476-32-0

Chemical Name:: Bromo-PEG4-t-butyl ester

Synonyms: 4,7,10,13-Tetraoxapentadecanoic acid, 15-bromo-, 1,1-dimethylethyl ester;Br-PEG4-C2-Boc;Br-PEG4-COOtBu;CAS_564476-32-0;Br-PEG4-CH2CH2COOtBu;Br-PEG4-t-butyl ester;t-Bu Ester-PEG4-Bromide;Bromo-PEG5-t-butyl ester;Bromo-PEG4-t-butyl ester;1,1-Dimethylethyl 15-bromo-4,7,10,13-tetraoxapentadecanoate

CBNumber:: CB03048720

Molecular Formula:: C15H29BrO6

Molecular Weight:: 385.29

MDL Number:: MFCD22574808

MOL File:: 564476-32-0.mol

MSDS File:: SDS

Last updated:2026-05-27 17:37:57

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Bromo-PEG4-t-butyl ester Properties

Boiling point	415.8±35.0 °C(Predicted)
Density	1.210±0.06 g/cm3(Predicted)
storage temp.	Storage temp. 2-8°C
solubility	Soluble in DMSO, DCM, DMF
form	Liquid
color	Colorless to light yellow
InChI	InChI=1S/C15H29BrO6/c1-15(2,3)22-14(17)4-6-18-8-10-20-12-13-21-11-9-19-7-5-16/h4-13H2,1-3H3
InChIKey	WLKHUFASPMJBHB-UHFFFAOYSA-N
SMILES	C(OC(C)(C)C)(=O)CCOCCOCCOCCOCCBr

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P280-P301+P312-P302+P352-P305+P351+P338

Bromo-PEG4-t-butyl ester price More Price(37)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	516858	Bromo-PEG4-T-Butly Ester (3,6,9,12-Tetraoxapentadecan-15-oic acid, 1-bromo-, 1,1-dimethylethylester) ≥95%	564476-32-0	1g	$559	2026-06-03	Buy
ChemScene	CS-0107159	Br-PEG4-C2-Boc ≥97%	564476-32-0	100mg	$18	2026-06-04	Buy
ChemScene	CS-0107159	Br-PEG4-C2-Boc ≥97%	564476-32-0	250mg	$21	2026-06-04	Buy
ChemScene	CS-0107159	Br-PEG4-C2-Boc ≥97%	564476-32-0	1g	$74	2026-06-04	Buy
ChemScene	CS-0107159	Br-PEG4-C2-Boc ≥97%	564476-32-0	5g	$342	2026-06-04	Buy

Product number	Packaging	Price	Buy
516858	1g	$559	Buy
CS-0107159	100mg	$18	Buy
CS-0107159	250mg	$21	Buy
CS-0107159	1g	$74	Buy
CS-0107159	5g	$342	Buy

Bromo-PEG4-t-butyl ester Chemical Properties,Uses,Production

Description

Bromo-PEG4-t-butyl ester is a PEG linker containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

Br-PEG4-C2-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Biological Activity

Br-PEG4-C2-Boc is a cleavable ADC linker containing 4 units of PEG, which can be used to synthesize antibody drug conjugates (ADC).

target

Cleavable

PEGs

Alkyl/ether

IC 50

Cleavable Linker; PEGs; Alkyl/ether

References

[1] Robert Yongxin Zhao, et al. Cytotoxic agents. WO2003068144A2.

Bromo-PEG4-t-butyl ester synthesis

Synthesis of Bromo-PEG4-t-butyl ester from Tos-PEG5 t-butyl ester

Bromo-PEG4-t-butyl ester Preparation Products And Raw materials

Raw materials

Tos-PEG5 t-butyl ester Hydroxy-PEG4-t-butyl ester tert-Butyl acrylate Carbon tetrabromide tetraethylene glycol

Preparation Products

Bromo-PEG4-t-butyl ester Suppliers

Global( 84)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Borenpharm Co., Ltd	027-65563561	sales@borenpharm.com	China	1245	55
Suzhou Highfine Biotech Co., Ltd	0512-69209928 18796809688	zhouyingxiang@highfine.com	China	1846	58
Chengdu Pukang Biotechnology Co., Ltd	18217049878	cassie.gao@pu-kang.com	China	479	58
T&W GROUP	021-61551611 13296011611	contact@trustwe.com	China	9884	58
Nanjing Junnahe Biopharmaceutical Co., Ltd	025-58367986 17351780683	amy.xiang@ally-chem.com	China	354	60
Bide Pharmatech Ltd.	400-164-7117 18317119277	product02@bidepharm.com	China	40000	60
Hunan HuaTeng Pharmaceutical Co., Ltd.,	400-8592883 15367835770	sales@huatengsci.com	China	5869	58
Shanghai YuanYe Biotechnology Co., Ltd.	15026964105	2881489226@qq.com	China	89667	60
Zhengzhou Acme Chemical Co., Ltd.	0371-0371-55629727 13323845623	2885676761@qq.com	China	9948	58
Amatek Scientific Co. Ltd.	0512-56316828 400-867-5858;400-867-5858	info@amateksci.com	China	28763	58

Supplier	Advantage
Borenpharm Co., Ltd	55
Suzhou Highfine Biotech Co., Ltd	58
Chengdu Pukang Biotechnology Co., Ltd	58
T&W GROUP	58
Nanjing Junnahe Biopharmaceutical Co., Ltd	60
Bide Pharmatech Ltd.	60
Hunan HuaTeng Pharmaceutical Co., Ltd.,	58
Shanghai YuanYe Biotechnology Co., Ltd.	60
Zhengzhou Acme Chemical Co., Ltd.	58
Amatek Scientific Co. Ltd.	58

View Lastest Price from Bromo-PEG4-t-butyl ester manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-04-20	Br-PEG4-C2-Boc 564476-32-0				10g	TargetMol Chemicals Inc.
	2025-06-07	Br-PEG4-COOtBu 564476-32-0		5g	>98.00%	5g	Xian confluore Biological Technology Co., Ltd.

Br-PEG4-C2-Boc
564476-32-0
$0.00
TargetMol Chemicals Inc.

Br-PEG4-COOtBu
564476-32-0
$0.00
>98.00%
Xian confluore Biological Technology Co., Ltd.

Bromo-PEG4-t-butyl ester Spectrum

Bromo-PEG4-t-butyl ester(564476-32-0)¹HNMR

564476-32-0(Bromo-PEG4-t-butyl ester)Related Search:

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1of4

CAS_564476-32-0 Bromo-PEG4-t-butyl ester Bromo-PEG5-t-butyl ester Br-PEG4-t-butyl ester Br-PEG4-CH2CH2COOtBu Br-PEG4-COOtBu Br-PEG4-C2-Boc 3,6,9,12-Tetraoxapentadecan-15-oic acid, 1-bromo-, 1,1-dimethylethylester Br-PEG4-CH2CH2COOtBu/4,7,10,13-Tetraoxapentadecanoic acid, 15-bromo-, 1,1-dimethylethyl ester tert-butyl 3-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]propanoate 1,1-Dimethylethyl 15-bromo-4,7,10,13-tetraoxapentadecanoate 4,7,10,13-Tetraoxapentadecanoic acid, 15-bromo-, 1,1-dimethylethyl ester t-Bu Ester-PEG4-Bromide 564476-32-0 C15H29BrO6