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tetraethylene glycol

CAS No.
112-60-7
Chemical Name:
tetraethylene glycol
Synonyms
TETRAETHYLENE GLYCOL;2,2'-((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethan-1-ol);TETRAGLYCOL;3,6,9-Trioxaundecane-1,11-diol;tetragol;OH-PEG4-OH;Tetraethylene glyco;Tetraethylene glycol, 99.5%;BIS[2-(2-HYDROXYETHOXY)ETHYL]ETHER;2,2'-((Oxybis(ethane-2,1-diyl))bis(oxy))diethanol
CBNumber:
CB7351725
Molecular Formula:
C8H18O5
Molecular Weight:
194.23
MDL Number:
MFCD00002879
MOL File:
112-60-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-06-24 18:39:39

tetraethylene glycol Properties

Melting point -5.6 °C (lit.)
Boiling point 314 °C (lit.)
Density 1.125 g/mL at 25 °C (lit.)
vapor density 6.7 (vs air)
vapor pressure <0.01 mm Hg
refractive index n20/D 1.459(lit.)
Flash point 400 °F
storage temp. Store below +30°C.
solubility 1000g/l
form Liquid
pka 14.06±0.10(Predicted)
color Clear slightly yellow
PH 8.5-9.0 (500g/l, H2O, 20℃)
explosive limit 0.5-3.4%(V)
Water Solubility soluble
Thermal Conductivity 0.187 W/(m·K) at 25 ℃
Specific Heat Capacity Cp(liquid): 2.21 J/(g·K), at 25℃
α-end hydroxyl
Ω-end hydroxyl
BRN 1634320
Henry's Law Constant 1.8×1013 mol/(m3Pa) at 25℃, HSDB (2015)
Stability Stable. Incompatible with strong oxidizing agents, strong bases.
InChI 1S/C8H18O5/c9-1-3-11-5-7-13-8-6-12-4-2-10/h9-10H,1-8H2
InChIKey UWHCKJMYHZGTIT-UHFFFAOYSA-N
SMILES OCCOCCOCCOCCO
LogP -2 at 25℃
Surface tension 44.72 mN/m at 303.15K
Indirect Additives used in Food Contact Substances POLYOXYETHYLENE(MW 200)
FDA 21 CFR 176.210
CAS DataBase Reference 112-60-7(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII R95B8J264J
NIST Chemistry Reference Ethanol, 2,2'-[oxybis(2,1-ethanediyloxy)]bis-(112-60-7)
EPA Substance Registry System Tetraethylene glycol (112-60-7)
UNSPSC Code 12352104
NACRES NA.23

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)
GHS05
Signal word  Warning
Hazard statements  H320
Precautionary statements  P264-P337+P313-P305+P351+P338
PPE Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Risk Statements  36/37/38
Safety Statements  24/25
WGK Germany  2
RTECS  XC2100000
Autoignition Temperature 340 °C DIN 51794
TSCA  TSCA listed
HS Code  29094919
Storage Class 10 - Combustible liquids
Hazardous Substances Data 112-60-7(Hazardous Substances Data)
Toxicity LD50 orally in Rabbit: > 18056 mg/kg LD50 dermal Rabbit > 18056 mg/kg
REACH Registrations Active
NFPA 704
1
1 0

tetraethylene glycol price More Price(62)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 110175 Tetraethylene glycol 99% 112-60-7 1kg $77.9 2026-04-30 Buy
Sigma-Aldrich 8.08619 Tetraethylene glycol for synthesis 112-60-7 1L $64.4 2026-04-30 Buy
Sigma-Aldrich 110175 Tetraethylene glycol 99% 112-60-7 3kg $196 2026-04-30 Buy
TCI Chemical T0099 Tetraethylene Glycol >95.0%(GC) 112-60-7 25g $17 2026-04-30 Buy
TCI Chemical T0099 Tetraethylene Glycol >95.0%(GC) 112-60-7 500g $21 2026-04-30 Buy
Product number Packaging Price Buy
110175 1kg $77.9 Buy
8.08619 1L $64.4 Buy
110175 3kg $196 Buy
T0099 25g $17 Buy
T0099 500g $21 Buy

tetraethylene glycol Chemical Properties, Uses, Production

Description

Tetraethylene glycol is a polymer consisting of ethylene glycol monomer units and two terminal hydroxyl groups. The hydroxyl groups can react to further derivatize the compound. Ethylene glycol compounds have hydrophilic characteristics. The solubility of the polymer increases as the number of ethylene glycol groups increase.

Chemical Properties

Tetraethylene glycol is a high-boiling, clear liquid of low volatility. hygroscopic. It is completely miscible with water and a wide variety of organic solvents. insoluble in benzene, toluene, or gasoline. Combustible. For certain aliphatic hydrocarbons, it has a very slight affinity. Tetraethylene glycol is used as a coupling agent for blending water-soluble and water-insoluble compounds in such formulations as lubricants, glues, cork and textile products, etc.

Uses

Solvent for nitrocellulose, plasticizer, lacquers, coating compositions.

Uses

Tetraethylene glycol is used as a solvent to dissolve water-insoluble compounds. It is employed as a nitrocellulose solvent, a plasticizer, a natural gas desiccant, a hydraulic fluid and in lacquers and coatings. Furthermore, it is used in the synthesis of tetraethylene glycol methacrylate monomer. It acts as a chemical intermediate and acts as a solvent for the manufacturing of inks and dyes. In addition, it serves as a coupling agent in the production of textile lubricants and formulations.

Definition

ChEBI: Tetraethylene glycol is a poly(ethylene glycol).

Production Methods

Tetraethylene glycol is prepared commercially by adding ethylene oxide to ethylene glycol, diethylene glycol, or water in the presence of a suitable catalyst.

General Description

Colorless to straw-colored liquid with a mild odor. Sinks and mixes with water.

Air & Water Reactions

Water soluble.

Reactivity Profile

Bis[2-(2-hydroxyethoxy)ethyl] ether is a ether-alcohol derivative. The ether being relatively unreactive. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert alcohols to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides. May attack some forms of plastics [USCG, 1999].

Health Hazard

Compound is nonirritating. No symptoms observed by any exposure route.

Flammability and Explosibility

Non flammable

Safety Profile

Mildly toxic by ingestion. A sktn and eye irritant. Combustible when exposed to heat or flame; can react with oxidzing materials. To fight fire, use alcohol foam, water, CO2, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes.

Global Suppliers ( 464)
Supplier Tel Email Country ProdList Advantage
Annular(Qihe)New Material Technology Co., Ltd 18600642180(微信同) 13391601435 1584468135@qq.com China 2037 58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29977 65
Shanghai Sphchem Co., Ltd. 021-56491756 13512199871 2819742715@qq.com China 3994 55
Changzhou Success Chemical Co., Ltd. 18961148122; 18961148122 278954761@qq.com China 34 58
Zhengzhou KeYulong chemical products Co., Ltd 17319789407 17319789407 Keyulongchem@163.com China 1996 55
Noventek Pharmaceutical Technology Co.,Ltd 0555-8220886 sales@noventekpharm.com China 176 58
Tianmen Hengchang Chemical Co., Ltd 027-59322316 15172518801 1208480077@qq.com China 9485 58
Nanjing Xinzeyue Chemical Co., Ltd. 025-15298392496 15298392496 1017019739@qq.com China 55 58
Dezhou Mengxuan Chemical Co., Ltd 19163510751 19163510751 207451738@QQ.com China 157 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76

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View Latest Price from tetraethylene glycol manufacturers

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Bis[2-(2-hydroxyethoxy)ethyl] ether pictures 2026-05-28 Bis[2-(2-hydroxyethoxy)ethyl] ether
112-60-7
$50.00-100.00 1KG 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
Glycofurol pictures 2026-01-24 Glycofurol
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1000kg 99% 600 tons Yunjian (Guangzhou) Import Export Trade Co., Ltd
Bis[2-(2-hydroxyethoxy)ethyl] ether pictures 2025-07-29 Bis[2-(2-hydroxyethoxy)ethyl] ether
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$6.00 1kg 99% 2000KG/Month HebeiShuoshengImportandExportco.,Ltd
  • Glycofurol pictures
  • Glycofurol
    112-60-7
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  • Yunjian (Guangzhou) Import Export Trade Co., Ltd
2,2'-Oxydiethylenedixoydiethanol octane-1,7-diol Bis[2-(2-hydroxyethoxy)ethyl] ether, Tetra(ethylene glycol), Tetraglycol 2,2'-[Oxybis(2,1-ethanediyloxy)]diethanol Tetraethylene glycol,Bis[2-(2-hydroxyethoxy)ethyl] ether, Tetra(ethylene glycol), Tetraglycol Tetraethylene glycol, 99.5% Tetraethylene glycol, 99.5% 1LT Tetraethylene glycol, 99.5% 2.5LT TETRAETHYLENE GLYCOL FOR SYNTHESIS 2,2'-((Oxybis(ethane-2,1-diyl))bis(oxy))diethanol Tetraethylene glyco Tetraethylene glycol, 99.5%, 99.5% TETRAETHYLENE GLYCOL TETRAGLYCOL 2-(2-(2-(2-hydroxy-ethoxy)-ethoxy)-ethoxy)-ethanol 2-(2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy)ethanol 2,2'-(Oxybis(ethyleneoxy))diethanol 2,2’-(oxybis(2,1-ethanediyloxy))bis-ethano Ethanol, 2,2'-(oxybis(ethyleneoxy))di- Hi-Dry Tetracthyleneglycol tetraethylenegylcol TetraHthylenglykol tetragol ETHANOLAMINE REAGENTPLUS(TM) >=99% Tetraethylene glycol, 99+% Tetraethylene glycol, 99.50% Ethanol, 2,2-oxybis(2,1-ethanediyloxy)bis- LIPOXOL 200 JACS-112-60-7 2,2’-(oxybis(ethyleneoxy))di-ethano 2,2’-[oxybis(2,1-ethanediyloxy)]bis-ethano 2,2’-[oxybis(2,1-ethanediyloxy)]bis-Ethanol 25322-68-33,6,9- 25322-68-33,6,9-trioxaundecane-1,11- 25322-68-33,6,9-trioxaundecane-1,11-diol 3,6,9-trioxa-undecan-1,11-diol 3,6,9-Trioxaundecan-1,11-diol Tetraethylene Glycol > Tetraethylene glycol, 99%, for synthesis PROTAC Linker 18 Bis[2-(2-Hydroxyethoxy)Ethyl] Ether,99% etraethyleneglycol Tetraethylene Glycol HP Tetraethylene glycol (6CI, 7CI, 8CI) 2,2'-[Piperazine-1,4-diyl bis(ethane-2,1-diyloxy)]diethanol Tetraethylene glycol in methanol Alcohol-PEG4-Alcohol 2,2'-((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethan-1-ol) 3,6,9-Trioxaundecane-1,11-diol BIS[2-(2-HYDROXYETHOXY)ETHYL]ETHER OH-PEG4-OH 112-60-7 HOCH2CH2O3CH2CH2OH 112607 C8H18O5 OCH2CH2OCH2CH2OH2 Ethylene Glycols