Propargyl-PEG2-methylamine
- CAS No.
- 1835759-76-6
- Chemical Name:
- Propargyl-PEG2-methylamine
- Synonyms
- Propargyl-PEG2-NHMe;Propargyl-PEG2-methylamine;Ethanamine, N-methyl-2-[2-(2-propyn-1-yloxy)ethoxy]-;Propargyl-PEG2-NHMe/Ethanamine, N-methyl-2-[2-(2-propyn-1-yloxy)ethoxy]-
- CBNumber:
- CB03062618
- Molecular Formula:
- C8H15NO2
- Molecular Weight:
- 157.21
- MDL Number:
- MOL File:
- 1835759-76-6.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P305+P351+P338 |
Propargyl-PEG2-methylamine price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0114296 | Propargyl-PEG2-methylamine ≥98% | 1835759-76-6 | 1g | $1805 | 2026-06-04 | Buy |
| BroadPharm | bp-22929 | Propargyl-PEG2-methylamine 98% | 1835759-76-6 | 100MG | $280 | 2026-05-24 | Buy |
| BroadPharm | bp-22929 | Propargyl-PEG2-methylamine 98% | 1835759-76-6 | 250MG | $460 | 2026-05-24 | Buy |
| BroadPharm | bp-22929 | Propargyl-PEG2-methylamine 98% | 1835759-76-6 | 500MG | $750 | 2026-05-24 | Buy |
| BroadPharm | bp-22929 | Propargyl-PEG2-methylamine 98% | 1835759-76-6 | 1G | $1100 | 2026-05-24 | Buy |
Propargyl-PEG2-methylamine Chemical Properties, Uses, Production
Description
Propargyl-PEG2-methylamine is a crosslinker with a propargyl group and methylamine group. The propargyl group forms triazole linkage with azide-bearing compounds or biomolecules in copper catalyzed Click Chemistry reactions. The methylamine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
Uses
Propargyl-PEG2-methylamine (Propargyl-PEG2-NHMe) is a PEG derivative containing a propargyl group and methylamine group. Propargyl-PEG2-methylamine is an PROTAC linker used in the synthesis of PROTACs. Propargyl-PEG2-methylamine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups[1].
References
[1] Wurz RP, et al. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation. J Med Chem. 2018 Jan 25;61(2):453-461. DOI:10.1021/acs.jmedchem.6b01781
Propargyl-PEG2-methylamine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80534353 19917294565 | et@chemextension.com | China | 3904 | 55 |
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6347 | 58 | |
| Amatek Scientific Co. Ltd. | 0512-56316828 400-867-5858;400-867-5858 | info@amateksci.com | China | 28760 | 58 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| Alpha Biopharmaceuticals Co., Ltd | 0411-39042497 | sales@alphabiopharm.com | China | 1951 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 13892832556 | 2440688701@qq.com | China | 1981 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 770406999@qq.com | China | 9949 | 58 |
| Shandong Dayou Pharmaceutical Research and Development Co., Ltd. | hanfangpharma@126.com 15165037910 | hanfangpharma@126.com | China | 25800 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
View Latest Price from Propargyl-PEG2-methylamine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-07 | Propargyl-PEG2-methylamine
1835759-76-6
|
500mg | >98.00% | 500mg | Xian confluore Biological Technology Co., Ltd. |
-
- Propargyl-PEG2-methylamine
1835759-76-6
- $0.00
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
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