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Biotin-PEG4-Methyltetrazine

Biotin-PEG4-Methyltetrazine Structure
Biotin-PEG4-Methyltetrazine structure
CAS No.
1835759-81-3
Chemical Name:
Biotin-PEG4-Methyltetrazine
Synonyms
Biotin-PEG4-MTz;Biotin-PEG4-Methyltetrazine;N-(2-(2-(2-(2-(4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenoxy)ethoxy)ethoxy)ethoxy)ethyl)-5-((3aR,4R,6aS)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide;1H-Thieno[3,4-d]imidazole-4-pentanamide, hexahydro-N-[2-[2-[2-[2-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]ethoxy]ethoxy]ethoxy]ethyl]-2-oxo-, (3aR,4R,6aS)-rel-
CBNumber:
CB83344947
Molecular Formula:
C27H39N7O6S
Molecular Weight:
589.71
MDL Number:
MFCD29052200
MOL File:
1835759-81-3.mol
MSDS File:
SDS
Last updated:2025-07-16 09:55:30
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Biotin-PEG4-Methyltetrazine Properties

Density 1.233±0.06 g/cm3(Predicted)
storage temp. 2-8°C, sealed storage, away from moisture
solubility Soluble in DMSO, DMF
pka 13.90±0.40(Predicted)
form Solid
color Purple to purplish red

Biotin-PEG4-Methyltetrazine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth KYC75981 Biotin-PEG4-methyltetrazine 1835759-81-3 50mg $910.5 2026-06-04 Buy
Biosynth KYC75981 Biotin-PEG4-methyltetrazine 1835759-81-3 100mg $1458 2026-06-04 Buy
ChemScene CS-0115305 Biotin-PEG4-methyltetrazine ≥98% 1835759-81-3 5mg $73 2026-06-04 Buy
ChemScene CS-0115305 Biotin-PEG4-methyltetrazine ≥98% 1835759-81-3 10mg $117 2026-06-04 Buy
dPEG CCT-1024-25 Biotin-PEG4-Methyltetrazine 25mg $259 2026-06-04 Buy
Product number Packaging Price Buy
KYC75981 50mg $910.5 Buy
KYC75981 100mg $1458 Buy
CS-0115305 5mg $73 Buy
CS-0115305 10mg $117 Buy
CCT-1024-25 25mg $259 Buy

Biotin-PEG4-Methyltetrazine Chemical Properties, Uses, Production

Description

Biotin-PEG4-methyltetrazine is a click chemistry biotinylation reagent that can react with TCO-containing compounds to form a stable covalent bond without the catalysis of Cu or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity.

Uses

Biotin-PEG4-methyltetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Biotin-PEG4-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Biotin-PEG4-Methyltetrazine Preparation Products And Raw materials

Raw materials

Preparation Products

Biotin-PEG4-Methyltetrazine Suppliers

Global Suppliers ( 43)
Supplier Tel Email Country ProdList Advantage
Jinan elephant international trading co., LTD 13006575422@163.com China 6347 58
Aikon International Limited 025-58859352 15955137747 sales01@aikonchem.com China 16021 58
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4229 58
Henan's chemical products co., LTD 0371-60919097 15378766539; 794449696@qq.com China 5000 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Shaanxi Xinyan Bomei Biotechnology Co., Ltd. 13892832556 2440688701@qq.com China 1981 58
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39866 58
Shanghai Kaiwei Chemical Technology Co., Ltd. 021-58461859 15821823057 service@aiviche.com China 49299 58
Taizhou Nanfeng Pharmaceutical Research Institute nanfengpharma@126.co 18616377689 nanfengpharma@126.com China 20008 58
Supplier Advantage
Jinan elephant international trading co., LTD 58
Aikon International Limited 58
Xi'an Confluore Biological Technology Co., Ltd. 58
Henan's chemical products co., LTD 58
Shanghai Hongye Biotechnology Co. Ltd 58
TargetMol Chemicals Inc. 58
Shaanxi Xinyan Bomei Biotechnology Co., Ltd. 58
Chongqing Chemdad Co., Ltd 58
Shanghai Kaiwei Chemical Technology Co., Ltd. 58
Taizhou Nanfeng Pharmaceutical Research Institute 58

View Latest Price from Biotin-PEG4-Methyltetrazine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Biotin-PEG4-methyltetrazine pictures 2025-06-07 Biotin-PEG4-methyltetrazine
1835759-81-3
 25mg >97.00% 100mg Xian confluore Biological Technology Co., Ltd.

1835759-81-3 (Biotin-PEG4-Methyltetrazine) Related Search:

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Biotin-PEG4-Methyltetrazine 1H-Thieno[3,4-d]imidazole-4-pentanamide, hexahydro-N-[2-[2-[2-[2-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]ethoxy]ethoxy]ethoxy]ethyl]-2-oxo-, (3aR,4R,6aS)-rel- N-(2-(2-(2-(2-(4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenoxy)ethoxy)ethoxy)ethoxy)ethyl)-5-((3aR,4R,6aS)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide Biotin-PEG4-MTz 1835759-81-3 C27H39N7O6S