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ChemicalBook >> CAS DataBase List >>1-Bromo-4,5-difluoro-2-methyl-benzene

1-Bromo-4,5-difluoro-2-methyl-benzene

1-Bromo-4,5-difluoro-2-methyl-benzene Structure
1-Bromo-4,5-difluoro-2-methyl-benzene structure
CAS No.
875664-38-3
Chemical Name:
1-Bromo-4,5-difluoro-2-methyl-benzene
Synonyms
2-BROMO-4,5-DIFLUOROTOLUENE;2-Bromo-4,5-difluorotoluene >4,5-DIFLUORO-2-METHYLBROMOBENZENE;1-Bromo-4,5-difluoro-2-methyl-benzene;1-brommo-4,5-difluoro-2-methyl-benzene;Benzene, 1-bromo-4,5-difluoro-2-methyl-
CBNumber:
CB0309873
Molecular Formula:
C7H5BrF2
Molecular Weight:
207.02
MDL Number:
MFCD07777160
MOL File:
875664-38-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:48:06
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1-Bromo-4,5-difluoro-2-methyl-benzene Properties

Boiling point 183.5±35.0 °C(Predicted)
Density 1.588±0.06 g/cm3(Predicted)
refractive index 1.508
storage temp. Sealed in dry,Room Temperature
form clear liquid
color Colorless to Almost colorless
InChIKey FKEURBCLFHOBDM-UHFFFAOYSA-N
CAS DataBase Reference 875664-38-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H227-H315-H319-H335
Precautionary statements  P210-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P403+P235-P501-P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Risk Statements  20/21/22-36/37/38
Safety Statements  26-36/37/39
HS Code  2904990090
NFPA 704
1
2 0

1-Bromo-4,5-difluoro-2-methyl-benzene price More Price(46)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical B4129 2-Bromo-4,5-difluorotoluene >98.0%(GC) 875664-38-3 1g $31 2026-04-30 Buy
TCI Chemical B4129 2-Bromo-4,5-difluorotoluene >98.0%(GC) 875664-38-3 5g $99 2026-04-30 Buy
Apolloscientific PC53115 2-Bromo-4,5-difluorotoluene 98% 875664-38-3 1g $21 2026-06-04 Buy
Apolloscientific PC53115 2-Bromo-4,5-difluorotoluene 98% 875664-38-3 5g $39 2026-06-04 Buy
Apolloscientific PC53115 2-Bromo-4,5-difluorotoluene 98% 875664-38-3 10g $74 2026-06-04 Buy
Product number Packaging Price Buy
B4129 1g $31 Buy
B4129 5g $99 Buy
PC53115 1g $21 Buy
PC53115 5g $39 Buy
PC53115 10g $74 Buy

1-Bromo-4,5-difluoro-2-methyl-benzene Chemical Properties, Uses, Production

Synthesis

3,4-Difluorotoluene

2927-34-6

1-BROMO-4,5-DIFLUORO-2-METHYL-BENZENE

875664-38-3

Step 1: Synthesis of 1-bromo-4,5-difluoro-2-methylbenzene (16). Bromine (Br2) (40 g, 250 mmol) was added slowly and dropwise to a reaction flask containing 3,4-difluorotoluene (15) (27 g, 210 mmol) and iron powder (600 mg, 10 mmol) under ice bath conditions. The reaction mixture was slowly warmed to room temperature with stirring and the reaction was continued for 12 hours. Upon completion of the reaction, the reaction was quenched by the addition of water and the mixture was extracted with ether. The combined organic layers were washed sequentially with sodium thiosulfate solution and saturated brine and dried over anhydrous sodium sulfate (Na2SO4). The ether was removed by concentration under reduced pressure to give the target product 1-bromo-4,5-difluoro-2-methylbenzene (16) (36 g, 83% yield). 1H NMR (400 MHz, DMSO-d6): δ 7.78 (t, 1H), 7.52 (t, 1H), 2.29 (s, 3H).

References

[1] Patent: WO2017/4608, 2017, A1. Location in patent: Paragraph 0133
[2] Patent: US2011/112158, 2011, A1. Location in patent: Page/Page column 9

1-Bromo-4,5-difluoro-2-methyl-benzene Preparation Products And Raw materials

Raw materials

3,4-Difluorotoluene

Preparation Products

1-Bromo-4,5-difluoro-2-methyl-benzene Suppliers

Global Suppliers ( 137)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Ark Pharm, Inc. 847-367-3680 sales@arkpharminc.com United States 1669 56
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 0311-89250318 13582355795 master@sjzsdyn.com China 2776 65
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Shanghai Harvest Chemical Industrial Co., Ltd. 15721252604 17321035817 sales@harvest-chem.com China 2829 64
Tianjin Jinyuda Chemical Co., Ltd. 022-58013646 13011382049 sales@jinyudachem.com China 1976 55
Supplier Advantage
J & K SCIENTIFIC LTD. 76
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Ark Pharm, Inc. 56
Energy Chemical 61
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 65
Wuhan Chemwish Technology Co., Ltd 56
Shanghai Harvest Chemical Industrial Co., Ltd. 64
Tianjin Jinyuda Chemical Co., Ltd. 55

View Latest Price from 1-Bromo-4,5-difluoro-2-methyl-benzene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-BROMO-4,5-DIFLUORO-2-METHYL-BENZENE pictures 2021-08-12 1-BROMO-4,5-DIFLUORO-2-METHYL-BENZENE
875664-38-3
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
2-Bromo-4,5-difluorotoluene pictures 2021-07-02 2-Bromo-4,5-difluorotoluene
875664-38-3
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
1-BROMO-4,5-DIFLUORO-2-METHYL-BENZENE pictures 2020-01-13 1-BROMO-4,5-DIFLUORO-2-METHYL-BENZENE
875664-38-3
 $1.00 1KG 99% 100KG Career Henan Chemical Co

1-Bromo-4,5-difluoro-2-methyl-benzene Spectrum

1-BROMO-4,5-DIFLUORO-2-METHYL-BENZENE(875664-38-3)1HNMR

875664-38-3 (1-Bromo-4,5-difluoro-2-methyl-benzene) Related Search:

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1-brommo-4,5-difluoro-2-methyl-benzene 4,5-DIFLUORO-2-METHYLBROMOBENZENE 2-BROMO-4,5-DIFLUOROTOLUENE 2-Bromo-4,5-difluorotoluene > Benzene, 1-bromo-4,5-difluoro-2-methyl- 1-Bromo-4,5-difluoro-2-methyl-benzene 875664-38-3 Aromatic Halides (substituted)