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ChemicalBook >> CAS DataBase List >>2-chloro-N-{(2-(2,6-dioxo(3-piperidyl))-1,3-dioxoisoindolin-4-yl)methyl}acetamide

2-chloro-N-{(2-(2,6-dioxo(3-piperidyl))-1,3-dioxoisoindolin-4-yl)methyl}acetamide

2-chloro-N-{(2-(2,6-dioxo(3-piperidyl))-1,3-dioxoisoindolin-4-yl)methyl}acetamide Structure
2-chloro-N-{(2-(2,6-dioxo(3-piperidyl))-1,3-dioxoisoindolin-4-yl)methyl}acetamide structure
CAS No.
444287-49-4
Chemical Name:
2-chloro-N-{(2-(2,6-dioxo(3-piperidyl))-1,3-dioxoisoindolin-4-yl)methyl}acetamide
Synonyms
TNF-α-IN-1;TNF-α-IN-1;TNF-a-IN-1;TNFαIN1,TNF α IN 1;2-chloro-N-{(2-(2,6-dioxo(3-piperidyl))-1,3-dioxoisoindolin-4-yl)methyl}acetamide;2-Chloro-N-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]methyl]acetamide;Acetamide, 2-chloro-N-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]methyl]-
CBNumber:
CB03099247
Molecular Formula:
C16H14ClN3O5
Molecular Weight:
363.75246
MDL Number:
MFCD29053130
MOL File:
444287-49-4.mol
MSDS File:
SDS
Last updated:2026-07-27 17:00:41
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2-chloro-N-{(2-(2,6-dioxo(3-piperidyl))-1,3-dioxoisoindolin-4-yl)methyl}acetamide Properties

Boiling point 718.6±60.0 °C(Predicted)
Density 1.526±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: 200 mg/mL (549.83 mM)
form Solid
pka 10.70±0.40(Predicted)
color Light yellow to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Exclamation Mark (GHS07)
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H314
Precautionary statements  P264-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P403+P233-P501

2-chloro-N-{(2-(2,6-dioxo(3-piperidyl))-1,3-dioxoisoindolin-4-yl)methyl}acetamide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth USA28749 TNF-α-IN-1 444287-49-4 50mg $953 2026-06-05 Buy
Biosynth USA28749 TNF-α-IN-1 444287-49-4 100mg $1325 2026-06-05 Buy
ChemScene CS-0044670 TNF-α-IN-1 99.20% 444287-49-4 5mg $152 2026-06-04 Buy
ChemScene CS-0044670 TNF-α-IN-1 99.20% 444287-49-4 10mg $238 2026-06-04 Buy
ChemScene CS-0044670 TNF-α-IN-1 99.20% 444287-49-4 25mg $422 2026-06-04 Buy
Product number Packaging Price Buy
USA28749 50mg $953 Buy
USA28749 100mg $1325 Buy
CS-0044670 5mg $152 Buy
CS-0044670 10mg $238 Buy
CS-0044670 25mg $422 Buy

2-chloro-N-{(2-(2,6-dioxo(3-piperidyl))-1,3-dioxoisoindolin-4-yl)methyl}acetamide Chemical Properties, Uses, Production

Uses

TNF-α-IN-1 is a TNF-α inhibitor extracted from patent US20030096841A1, compound example I-7.

References

[1] Robarge M, et al. Isoindole-imide compounds, compositions, and uses thereof. US20030096841A1

2-chloro-N-{(2-(2,6-dioxo(3-piperidyl))-1,3-dioxoisoindolin-4-yl)methyl}acetamide Preparation Products And Raw materials

Raw materials

Preparation Products

2-chloro-N-{(2-(2,6-dioxo(3-piperidyl))-1,3-dioxoisoindolin-4-yl)methyl}acetamide Suppliers

Global Suppliers ( 26)
Supplier Tel Email Country ProdList Advantage
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 9780 55
Shanghai Chaolan Chemical Technology Center QQ：65489617 13301690235 Sales@ATKchemical.com China 9729 58
Beijing Solarbio Science & Tecnology Co., Ltd. 17801761073 18101056239 3193328036@qq.com China 28150 68
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9718 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Suzhou Chenrui Biotechnology Co. LTD 17625585511 1580084073@qq.com China 992 58
Shandong Territorial sea Biological Technology Co., LTD 15092083467 tangfenjiushililiang@leadhigh.com.cn China 2986 58
cjbscvictory 13348960310 13348960310 3003867561@qq.com China 10233 58
Supplier Advantage
Shanghai YuanYe Biotechnology Co., Ltd. 60
Tianjin Kailiqi Biotechnology Co., Ltd. 55
Shanghai Chaolan Chemical Technology Center 58
Beijing Solarbio Science & Tecnology Co., Ltd. 68
Fan De(Beijing) Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Suzhou Chenrui Biotechnology Co. LTD 58
Shandong Territorial sea Biological Technology Co., LTD 58
cjbscvictory 58

View Latest Price from 2-chloro-N-{(2-(2,6-dioxo(3-piperidyl))-1,3-dioxoisoindolin-4-yl)methyl}acetamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
TNF-α-IN-1 pictures 2026-07-27 TNF-α-IN-1
444287-49-4
 $113.00-653.00 98.82% 10g TargetMol Chemicals Inc.
  • TNF-α-IN-1 pictures
  • TNF-α-IN-1
    444287-49-4
  • $113.00-653.00
  • 98.82%
  • TargetMol Chemicals Inc.

444287-49-4 (2-chloro-N-{(2-(2,6-dioxo(3-piperidyl))-1,3-dioxoisoindolin-4-yl)methyl}acetamide) Related Search:

1H-Isoindole-1,3(2H)-dione, 5-amino-2-(1- methyl-2,6-dioxo-3-piperidinyl)- 2-chloro-N-{(2-(2,6-dioxo(3-piperidyl))-1,3-dioxoisoindolin-4-yl)methyl}acetamide 3-(5-Amino-1-oxo-isoindolin-2-yl)piperidine-2,6-dione 3-(4-Ethynyl-1-oxoisoindolin-2-yl)piperidine-2,6-dione 2,6-Piperidinedione, 3-[6-(aminomethyl)-1,3-dihydro-1-oxo-2H-isoindol-2-yl]-
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-methyl-

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2-chloro-N-{(2-(2,6-dioxo(3-piperidyl))-1,3-dioxoisoindolin-4-yl)methyl}acetamide TNF-α-IN-1 Acetamide, 2-chloro-N-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]methyl]- TNFαIN1,TNF α IN 1 TNF-a-IN-1 TNF-α-IN-1 2-Chloro-N-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]methyl]acetamide 444287-49-4