(+)-DHMEQ
- CAS No.
- 287194-41-6
- Chemical Name:
- (+)-DHMEQ
- Synonyms
- 6R)-DHMEQ;(1R,2R,6R)-DHMEQ;(+) DHMEQ,(+)DHMEQ;6R)-Dehydroxymethylepoxyquinomicin;(1R,2R,6R)-Dehydroxymethylepoxyquinomicin;2-hydroxy-N-[(1R,2R,6R)-2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]benzamide;Benzamide, 2-hydroxy-N-[(1R,2R,6R)-2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-
- CBNumber:
- CB03146604
- Molecular Formula:
- C13H11NO5
- Molecular Weight:
- 261.23
- MDL Number:
- MOL File:
- 287194-41-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
(+)-DHMEQ price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | MLA19441 | (+)-DHMEQ | 287194-41-6 | 10mg | $986.4 | 2026-06-04 | Buy |
| Biosynth | MLA19441 | (+)-DHMEQ | 287194-41-6 | 25mg | $1608.25 | 2026-06-04 | Buy |
| Biosynth | MLA19441 | (+)-DHMEQ | 287194-41-6 | 50mg | $2572.5 | 2026-06-04 | Buy |
| ChemScene | CS-5817 | (+)-DHMEQ 99.18% | 287194-41-6 | 2mg | $182 | 2026-06-04 | Buy |
| ChemScene | CS-5817 | (+)-DHMEQ 99.18% | 287194-41-6 | 5mg | $286 | 2026-06-04 | Buy |
(+)-DHMEQ Chemical Properties, Uses, Production
Uses
(+)-DHMEQ is an activator of antioxidant transcription factor Nrf2. (+)-DHMEQ is the enantiomer of (-)-DHMEQ. (-)-DHMEQ inhibits NF-kB than its enantiomer (+)-DHMEQ.
Biological Activity
(+)-DHMEQ is an activator of the antioxidant transcription factor Nrf2. It is the enantiomer of (-)-DHMEQ. And it inhibited NF-kB activity less than (-)-DHMEQ.
in vitro
(+)-DHMEQ ((2R,3R,4R)-DHMEQ) activates Nrf2, which is a transcription factor that induces the expression of multiple antioxidant enzymes. (+)-DHMEQ activates Nrf2 in a promoter reporter assay.
target
Nrf2
References
[1] Niitsu Y, et al. Chemoenzymatic synthesis of (2R,3R,4R)-dehydroxymethylepoxyquinomicin (DHMEQ), a newactivator of antioxidant transcription factor Nrf2. Org Biomol Chem. 2011 Jun 21;9(12):4635-41. DOI:10.1039/c1ob05205e
(+)-DHMEQ Preparation Products And Raw materials
Raw materials
Preparation Products
(+)-DHMEQ Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7545 | 61 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Musechem | +1-800-259-7612 | info@musechem.com | United States | 4648 | 60 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Shanghai hongqu biomedical technology co. LTD | 88888888888 | hongquchem@qq.com | China | 5123 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
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