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(+)-DHMEQ manufacturers
- (+)-DHMEQ
-
- $2810.00
-
2026-05-21
- CAS:287194-41-6
- Purity:
- Supply Ability: 10g
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| | (+)-DHMEQ Basic information |
| Product Name: | (+)-DHMEQ | | Synonyms: | 2-hydroxy-N-[(1R,2R,6R)-2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]benzamide;(1R,2R,6R)-Dehydroxymethylepoxyquinomicin;(1R,2R,6R)-DHMEQ;Benzamide, 2-hydroxy-N-[(1R,2R,6R)-2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-;6R)-Dehydroxymethylepoxyquinomicin;6R)-DHMEQ;(+) DHMEQ,(+)DHMEQ | | CAS: | 287194-41-6 | | MF: | C13H11NO5 | | MW: | 261.23 | | EINECS: | | | Product Categories: | | | Mol File: | 287194-41-6.mol |  |
| | (+)-DHMEQ Chemical Properties |
| Melting point | 184 °C | | Boiling point | 617.2±55.0 °C(Predicted) | | density | 1.58±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : ≥ 35 mg/mL (133.98 mM) | | pka | 8.43±0.30(Predicted) | | form | Solid | | color | White to off-white |
| | (+)-DHMEQ Usage And Synthesis |
| Uses | (+)-DHMEQ is an activator of antioxidant transcription factor Nrf2. (+)-DHMEQ is the enantiomer of (-)-DHMEQ. (-)-DHMEQ inhibits NF-kB than its enantiomer (+)-DHMEQ. | | Biological Activity | (+)-DHMEQ is an activator of the antioxidant transcription factor Nrf2. It is the enantiomer of (-)-DHMEQ. And it inhibited NF-kB activity less than (-)-DHMEQ. | | in vitro | (+)-DHMEQ ((2R,3R,4R)-DHMEQ) activates Nrf2, which is a transcription factor that induces the expression of multiple antioxidant enzymes. (+)-DHMEQ activates Nrf2 in a promoter reporter assay. | | target | | | References | [1] Niitsu Y, et al. Chemoenzymatic synthesis of (2R,3R,4R)-dehydroxymethylepoxyquinomicin (DHMEQ), a newactivator of antioxidant transcription factor Nrf2. Org Biomol Chem. 2011 Jun 21;9(12):4635-41. DOI:10.1039/c1ob05205e |
| | (+)-DHMEQ Preparation Products And Raw materials |
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