(R)-N-(1-amino-5-(2-chloroacetamidino)-1-oxopentan-2-yl)benzamide hydrochloride
- CAS No.
- 2985338-61-0
- Chemical Name:
- (R)-N-(1-amino-5-(2-chloroacetamidino)-1-oxopentan-2-yl)benzamide hydrochloride
- Synonyms
- (R)-N-(1-amino-5-(2-chloroacetamidino)-1-oxopentan-2-yl)benzamide hydrochloride;Benzamide, N-[(1R)-1-(aminocarbonyl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-, hydrochloride (1:1)
- CBNumber:
- CB03165885
- Molecular Formula:
- C14H19ClN4O2.ClH
- Molecular Weight:
- 347.24
- MDL Number:
- MOL File:
- 2985338-61-0.mol
- MSDS File:
- SDS
(R)-N-(1-amino-5-(2-chloroacetamidino)-1-oxopentan-2-yl)benzamide hydrochloride price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0173459 | D-Cl-amidine hydrochloride 99.91% | 2985338-61-0 | 5mg | $271 | 2026-06-04 | Buy |
| ChemScene | CS-0173459 | D-Cl-amidine hydrochloride 99.91% | 2985338-61-0 | 10mg | $412 | 2026-06-04 | Buy |
| ChemScene | CS-0173459 | D-Cl-amidine hydrochloride 99.91% | 2985338-61-0 | 25mg | $812 | 2026-06-04 | Buy |
| ChemScene | CS-0173459 | D-Cl-amidine hydrochloride 99.91% | 2985338-61-0 | 50mg | $1300 | 2026-06-04 | Buy |
| ChemScene | CS-0173459 | D-Cl-amidine hydrochloride 99.91% | 2985338-61-0 | 100mg | $1950 | 2026-06-04 | Buy |
(R)-N-(1-amino-5-(2-chloroacetamidino)-1-oxopentan-2-yl)benzamide hydrochloride Chemical Properties, Uses, Production
Uses
D-Cl-amidine hydrochloride is a potent and highly selective PAD1 inhibitor. D-Cl-amidine is well-torelated with no significant toxicity[1].
in vivo
D-Cl-amidine, administered by iv at a dose of 2.5 mg/kg, is still detected after 2 h in serum at a concentration of ~21 nM and at 4 h at ~10 nM. D-Cl-amidine is still observed in the blood serum at a concentration of ～10 nM at 4 h when administered by ip at a dose of 10 mg/kg[1].
References
[1] Bicker KL, et al. D-amino acid based protein arginine deiminase inhibitors: Synthesis, pharmacokinetics, and in cellulo efficacy. ACS Med Chem Lett. 2012 Oct 26;3(12):1081-1085. DOI:10.1021/ml300288d
(R)-N-(1-amino-5-(2-chloroacetamidino)-1-oxopentan-2-yl)benzamide hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
(R)-N-(1-amino-5-(2-chloroacetamidino)-1-oxopentan-2-yl)benzamide hydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nantong MYBio-pharm. Co., Ltd. | 0513-85921823 18662920231 | sales@ntminyanmedical.com | China | 4563 | 58 |
| Nantong puyue biomedical Co., Ltd | 0513-0513-0513-89158300 18014392889 | sales@puyerbiopharma.com | China | 4956 | 58 |
| Supplier | Advantage |
|---|---|
| Nantong MYBio-pharm. Co., Ltd. | 58 |
| Nantong puyue biomedical Co., Ltd | 58 |
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