ChemicalBook >> CAS DataBase List >>2,4,6-Octatrienoicacid, 7-[3,5-bis(1,1-dimethylethyl)phenyl]-3-methyl-, (2E,4E,6E)-

2,4,6-Octatrienoicacid, 7-[3,5-bis(1,1-dimethylethyl)phenyl]-3-methyl-, (2E,4E,6E)-

CAS No.
178600-20-9
Chemical Name:
2,4,6-Octatrienoicacid, 7-[3,5-bis(1,1-dimethylethyl)phenyl]-3-methyl-, (2E,4E,6E)-
Synonyms
LG1550;LG-1550;LGD-1550;ALRT1550;ALRT-550;ALRT-1550;ALRT 1550;LGD-1550 = ALRT-1550;2,4,6-Octatrienoicacid, 7-[3,5-bis(1,1-dimethylethyl)phenyl]-3-methyl-, (2E,4E,6E)-
CBNumber:
CB03286140
Molecular Formula:
C23H32O2
Molecular Weight:
340.49898
MDL Number:
MOL File:
178600-20-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-11 15:21:01

2,4,6-Octatrienoicacid, 7-[3,5-bis(1,1-dimethylethyl)phenyl]-3-methyl-, (2E,4E,6E)- Properties

FDA UNII H62AOA2IYF

2,4,6-Octatrienoicacid, 7-[3,5-bis(1,1-dimethylethyl)phenyl]-3-methyl-, (2E,4E,6E)- Chemical Properties, Uses, Production

Uses

ALRT1550 (LGD1550) is a selective retinoic acid receptor (RAR) agonist that binds RARs with exceptional potency, with Kd values of approximately 1-4 nM. ALRT1550 exhibits anti-proliferative activity, with an IC50 value of 0.22 nM in UMSCC-22B squamous carcinoma cells. In a mouse tumor xenograft model, ALRT1550 inhibited tumor growth in a dose-dependent manner, achieving a maximum inhibition rate of 89%. ALRT1550 is applicable for research in the field of cancer[1][2].

References

[1] Shalinsky DR, et al. A novel retinoic acid receptor-selective retinoid, ALRT1550, has potent antitumor activity against human oral squamous carcinoma xenografts in nude mice. Cancer Res. 1997 Jan 1;57(1):162-8. PMID:8988059
[2] Zhang L, et al. Discovery of novel retinoic acid receptor agonists having potent antiproliferative activity in cervical cancer cells. J Med Chem. 1996 Jul 5;39(14):2659-63. DOI:10.1021/jm960285j

2,4,6-Octatrienoicacid, 7-[3,5-bis(1,1-dimethylethyl)phenyl]-3-methyl-, (2E,4E,6E)- Preparation Products And Raw materials

Raw materials

Preparation Products

2,4,6-Octatrienoicacid, 7-[3,5-bis(1,1-dimethylethyl)phenyl]-3-methyl-, (2E,4E,6E)- Suppliers

Global Suppliers ( 6)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Suzhou Meishi Biotechnology Co., Ltd. 1173954148q meishipharma@126.com China 20027 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 5985 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58

View Latest Price from 2,4,6-Octatrienoicacid, 7-[3,5-bis(1,1-dimethylethyl)phenyl]-3-methyl-, (2E,4E,6E)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ALRT 1550 pictures 2026-05-11 ALRT 1550
178600-20-9
$1520.00-2500.00 10g TargetMol Chemicals Inc.
  • ALRT 1550 pictures
  • ALRT 1550
    178600-20-9
  • $1520.00-2500.00
  • TargetMol Chemicals Inc.
2,4,6-Octatrienoicacid, 7-[3,5-bis(1,1-dimethylethyl)phenyl]-3-methyl-, (2E,4E,6E)- ALRT 1550 ALRT1550 ALRT-1550 ALRT-550 LG1550 LG-1550 LGD-1550 LGD-1550 = ALRT-1550 178600-20-9