5-Methyl-2,1,3-benzothiadiazole
- CAS No.
- 1457-93-8
- Chemical Name:
- 5-Methyl-2,1,3-benzothiadiazole
- Synonyms
- 5-Methylbenzo[c][1,2,5]thiadiazole;BUTTPARK 33\04-40;5-Methylpiazthiole;5-Methyl-2,1,3-benzothiadiazole;5-METHYLBENZO-2,1,3-THIADIAZOLE;5-methyl-benzo[1,2,5]thiadiazole;2,1,3-Benzothiadiazole, 5-methyl-
- CBNumber:
- CB0330127
- Molecular Formula:
- C7H6N2S
- Molecular Weight:
- 150.2
- MDL Number:
- MFCD00173945
- MOL File:
- 1457-93-8.mol
- MSDS File:
- SDS
| Melting point | 31-32° |
|---|---|
| Boiling point | 62 °C |
| Density | 1.297±0.06 g/cm3 (20 ºC 760 Torr) |
| Flash point | 92.6±9.1℃ |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 0.59±0.47(Predicted) |
| Appearance | Light yellow to yellow Solid-Liquid Mixture |
| CAS DataBase Reference | 1457-93-8 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302-H314-H318 |
| Precautionary statements | P260-P264-P270-P280-P301+P312-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P321-P330-P363-P405-P501 |
| Hazard Note | Harmful |
| HazardClass | IRRITANT |
| HS Code | 2934999090 |
5-Methyl-2,1,3-benzothiadiazole price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | BAA45793 | 5-Methylbenzo[c][1,2,5]thiadiazole | 1457-93-8 | 2.5g | $437.5 | 2026-06-04 | Buy |
| Apolloscientific | OR26809 | 5-Methyl-2,1,3-benzothiadiazole ≥95% | 1457-93-8 | 250mg | $21 | 2026-06-04 | Buy |
| Activate Scientific | AS113330 | 5-Methylbenzo[c][1,2,5]thiadiazole 97% | 1457-93-8 | 1g | $157 | 2026-06-04 | Buy |
| Activate Scientific | AS113330 | 5-Methylbenzo[c][1,2,5]thiadiazole 97% | 1457-93-8 | 5g | $471 | 2026-06-04 | Buy |
| Matrix Scientific | 302412 | 5-Methylbenzo[c][1,2,5]thiadiazole | 1457-93-8 | 250.00mg | $49 | 2026-05-19 | Buy |
5-Methyl-2,1,3-benzothiadiazole Chemical Properties, Uses, Production
Definition
ChEBI: 5-Methyl-2,1,3-benzothiadiazole is a benzothiadiazole.
Synthesis
496-72-0
1457-93-8
(1) To a 250 mL three-neck flask was added 4-methylbenzene-1,2-diamine (3.75 g, 30 mmol) and dichloromethane (60 mL) followed by trimethylamine (13.14 g, 130 mmol). The mixture was stirred until 4-methylbenzene-1,2-diamine was completely dissolved. Under stirring, sulfurous dichloride (11.47 g, 100 mmol) was slowly added dropwise and then the reaction mixture was heated to reflux for 5 hours. Upon completion of the reaction, the reaction was quenched with 1 mol/L sodium hydroxide solution and subsequently extracted with dichloromethane (30 mL x 3). The organic phases were combined and concentrated by rotary evaporator. The crude product was purified by silica gel column chromatography using petroleum ether as eluent to afford brown needle-like crystals of 5-methyl-2,1,3-benzothiadiazole (3.69 g, 82% yield). The product characterization data were as follows: melting point 33-34 °C; 1H NMR (CDCl3, 400 MHz, TMS): δ 7.88 (d, 1H, J = 9 Hz), 7.76 (s, 1H), 7.43 (d, 1H, J = 9 Hz), 2.55 (s, 3H); 13C NMR (CDCl3, 100 MHz, TMS): δ 155.31, 153.54, 139.94, 132.41, 120.66, 119.76, 21.91; EIMS [M+]: calculated value 150.0252, measured value 150.0251.
References
[1] Tetrahedron, 2016, vol. 72, # 9, p. 1244 - 1248
[2] Tetrahedron, 2017, vol. 73, # 19, p. 2824 - 2830
[3] Journal of Polymer Science, Part A: Polymer Chemistry, 2016, vol. 54, # 5, p. 668 - 677
[4] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 4, p. 657 - 667
[5] Chemische Berichte, 1889, vol. 22, p. 2897
5-Methyl-2,1,3-benzothiadiazole Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Baiyin Chengze Chemical Technology Co., Ltd. | +86 943-8535351 13389336721 | sales@chengzechem.com | China | 300 | 58 |
| Shanghai Litong Chemical Technology Co.,Ltd. | 13598610367 0373-7129549 | 2468833170@qq.com | China | 932 | 58 |
| Shanghai ChuangYan Chemical Technology Co., Ltd. | 021-11111111 11111111111 | 546919421@qq.com | China | 3797 | 55 |
| Zhengzhou Guancheng Laboratory equipment Sales | 0371-88888888 qq272369594;2159423853qq | 2723695949@qq.com | China | 5000 | 50 |
| Changzhou Hopschain Chemical Co.,Ltd. | 85528066 13775048983 | sales@hopschem.com | China | 31548 | 55 |
| NanJing Xienuo bio Co.,Ltd. | 025-84112752 13805181430 | 154301870@qq.com | China | 999 | 55 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Henan Alfachem Co.,Ltd. | 0371-55051623 18137891487 | 3983243027@qq.com | China | 9990 | 58 |
View Latest Price from 5-Methyl-2,1,3-benzothiadiazole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-10-21 | 5-methyl-2,1,3-benzothiadiazole
1457-93-8
|
1kg | 99.0%min | 2tons/month | Asia Chem I and E (Jiangsu) Co Ltd |
-
- 5-methyl-2,1,3-benzothiadiazole
1457-93-8
- 99.0%min
- Asia Chem I and E (Jiangsu) Co Ltd
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