Dihydrobromide
- CAS No.
- 5913-82-6
- Chemical Name:
- Dihydrobromide
- Synonyms
- Conessine HCl;Conessine hydrobromide;Neriine dihydrobromide;Konessin dihydrobromide
- CBNumber:
- CB03357394
- Molecular Formula:
- C24H41BrN2
- Molecular Weight:
- 437.51
- MDL Number:
- MOL File:
- 5913-82-6.mol
| Melting point | 340 °C |
|---|---|
| alpha | D20 +7.0° (c = 5 in H2O) |
| FDA UNII | N9EQE108I5 |
Dihydrobromide Chemical Properties, Uses, Production
Uses
Conessine dihydrobromide is a steroidal alkaloid and an effective, selective histamine H3 receptor antagonist with Ki values of 5.4, 6.0, 5.7, and 25 nM for human, dog, guinea pig, and rat H3 receptors, respectively. Conessine dihydrobromide exhibits antimalarial activity and can be used in infection-related research[1][2].
Definition
ChEBI: Conessine dihydrobromide is a steroid alkaloid.
References
[1] Santora VJ, et al. A new family of H3 receptor antagonists based on the natural product Conessine. Bioorg Med Chem Lett. 2008;18(4):1490-1494 DOI:10.1016/j.bmcl.2007.12.059
[2] Kim H, et al. Conessine treatment reduces dexamethasone-induced muscle atrophy by regulating MuRF1 and atrogin-1 expression [published online ahead of print, 2018 Feb 1]. J Microbiol Biotechnol. 2018;10.4014.jmb.1711.11009 PMID:29385661
Dihydrobromide Preparation Products And Raw materials
Raw materials
Preparation Products
Dihydrobromide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
